Abstract: The present disclosure provides methods and systems for foam control. A method of foam control for a fermentation system comprises: obtaining image data from an imaging device located at the fermentation system; and processing said sensor data using a trained machine learning algorithm to generate an output that indicates presence of foam or level of foaming.

Abstract: A bioreactor may comprise a head-plate configured to provide coupling features to attach selected components to the bioreactor. The bioreactor may also comprise impeller and sparger, and the sparger is positioned at a pre-determined distance from the impeller based at least in part on a spatial configuration of the head-plate. The bioreactor further comprises a vessel defining a hollow enclosure for receiving a culture medium, and an opening of the vessel is covered by the head-plate.

Abstract: A system for controlling a fermentation system is described. The system can be controlled remotely by a user via cloud-based access to a computing platform connected to the fermentation system. A user can enter in an experimental protocol and make changes to the protocol in real-time.

Abstract: A fermentation automation workcell is provided. The fermentation automation workcell may permit automated seed train preparation, fermentation, and post-fermentation sample handling. The fermentation automation workcell may include one or more robotic handling devices that may aid in the automated process. A bioreactor array may include a plurality of modularized bioreactors that may be individually varied and/or controlled.