Patents by Inventor Matthew Alexander Holden

Matthew Alexander Holden has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Bilayers
    Patent number: 8784929
    Abstract: A method for producing a bilayer of amphipathic molecules comprising providing a hydrated support and providing a hydrophilic body, and bringing the hydrated support and hydrophilic body into contact to form a bilayer of amphipathic molecules. A bilayer produced by the method of the invention, and uses of the bilayer.
    Type: Grant
    Filed: October 16, 2012
    Date of Patent: July 22, 2014
    Assignee: Isis Innovation Limited
    Inventors: Mark Ian Wallace, Andrew John Heron, Matthew Alexander Holden
  • Delivery of molecules to a lipid bilayer
    Patent number: 7939270
    Abstract: A method of delivering a molecule, such as a membrane protein, to a lipid bilayer uses a probe capable of holding the molecule on a carrier surface thereof. The molecule is deposited on the carrier surface and the probe is moved to engage the carrier surface against the lipid bilayer. The carrier surface may be the surface of a drop of hydrogel which adsorbs the molecule. The molecule may be a membrane protein which is thus inserted into the lipid bilayer. The method is fast and simple to perform thereby allowing high throughput experimentation.
    Type: Grant
    Filed: March 22, 2006
    Date of Patent: May 10, 2011
    Assignee: Isis Innovation Limited
    Inventors: Matthew Alexander Holden, John Hagan Pryce Bayley
  • Delivery of Molecules to a Lipid Bilayer
    Publication number: 20080153150
    Abstract: A method of delivering a molecule, such as a membrane protein, to a lipid bilayer uses a probe capable of holding the molecule on a carrier surface thereof. The molecule is deposited on the carrier surface and the probe is moved to engage the carrier surface against the lipid bilayer. The carrier surface may be the surface of a drop of hydrogel which adsorbs the molecule. The molecule may be a membrane protein which is thus inserted into the lipid bilayer. The method is fast and simple to perform thereby allowing high throughput experimentation.
    Type: Application
    Filed: March 22, 2006
    Publication date: June 26, 2008
    Inventors: Matthew Alexander Holden, John Hagan Pryce Bayley