Abstract: A fluorometer can comprise a microfluidics chip receptacle configured to receive a microfluidics chip. The fluorometer can comprise a reflective enclosure that has an outer surface and an inner surface. The microfluidics chip receptacle can be configured in relation to the reflective enclosure so that the reflective enclosure can receive, at the inner surface, light energy emitted from an analyte on a microfluidics chip disposed in the microfluidics chip receptacle. The fluorometer can comprise an excitation source configured to emit excitation energy to the microfluidics chip receptacle. The fluorometer can comprise a light sensor configured in relation to the microfluidics chip receptacle to receive light energy from the microfluidics chip receptacle. The light energy, caused by the excitation energy, is emitted from an analyte. The fluorometer can comprise a controller configured to determine a concentration of an analyte from the light energy received at the light sensor.