Patents by Inventor Matthew B. Applegate

Matthew B. Applegate has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Silk-fibroin hydrogels, methods of forming, and uses thereof
    Patent number: 11833272
    Abstract: The present disclosure provides transparent, elastic silk hydrogels for applications, including corneal reshaping to restore visual acuity and photolithography. The present disclosure also provides methods of photocrosslinking silk fibroin protein using riboflavin as a photoinitiator and exposing such riboflavin doped silk fibroin to light resulting in the formation of a transparent, elastic hydrogel.
    Type: Grant
    Filed: December 16, 2016
    Date of Patent: December 5, 2023
    Assignee: Trustees of Tufts College
    Inventors: Fiorenzo G. Omenetto, Matthew B. Applegate, David L. Kaplan
  • Silk-Fibroin Hydrogels, Methods of Forming, and Uses Thereof
    Publication number: 20200069845
    Abstract: The present disclosure provides transparent, elastic silk hydrogels for applications, including corneal reshaping to restore visual acuity and photolithography. The present disclosure also provides methods of photocrosslinking silk fibroin protein using riboflavin as a photoinitiator and exposing such riboflavin doped silk fibroin to light resulting in the formation of a transparent, elastic hydrogel.
    Type: Application
    Filed: December 16, 2016
    Publication date: March 5, 2020
    Inventors: Fiorenzo G. Omenetto, Matthew B. Applegate, David L. Kaplan
  • SCAFFOLDS AND METHODS OF MAKING AND USING THE SAME
    Publication number: 20180071434
    Abstract: The present disclosure relates to scaffolds such as protein hydrogel scaffolds. The present disclosure provides methods and technologies that permit formation of cavities within hydrogel scaffolds; in some embodiments, such technologies permit controlled formation of cavities of particular predetermined shape and/or arrangement. In particular embodiments, the present disclosure provides multiphoton absorption technologies that achieve production of cavity-containing scaffolds.
    Type: Application
    Filed: September 15, 2016
    Publication date: March 15, 2018
    Inventors: Fiorenzo G. Omenetto, David L. Kaplan, Matthew B. Applegate