Abstract: The present disclosure describes methods and systems for interpreting a user external data reference value and a user data change input value, accessing an external data source in response to the user external data reference value, receiving source data from the external data source, updating the source data in the external data source in response to the external data source and the user data change input value, and providing an updated display value for a document in response to the user data change input value and the source data.

Abstract: Systems and methods include interpreting a first user input from a first user, the first user input comprising a text flow entry, interpreting a second user input from the first user, the second user input comprising at least one of: an in-line data access entry or a table-based calculation entry, positioning a text entry value on a unified document surface in response to the first user input, creating at least one data structure in response to the second user input, the at least one data structure comprising data from an external data source, the external data source being external to the unified document surface, and positioning the at least one data structure on the unified document surface.

Abstract: The present disclosure describes methods and systems for a accessing a data element, providing a first view in response to the data element, the first view comprising at least a portion of the data element, determining a visualization element (VE) in response to the data element, and further in response to at least one of a user visualization selection or a user context value, and providing a second view in response to the VE and the data element.

Abstract: The invention includes compositions and methods useful for the diagnosis and treatment of head or brain injury in a subject in need thereof, based upon the expression level of at least one miRNA that is associated with head or brain injury.

Abstract: The present disclosure describes methods and systems for interpreting a table grouping input value associated with a table, wherein the table comprises a plurality of categories and a plurality of associated data sets corresponding to the plurality of categories, determining an aggregation value in response to the table grouping input value, wherein the aggregation value corresponds to at least one of the plurality of categories, and in response to the aggregation value, providing an aggregated table view.

Abstract: The present disclosure describes methods and systems for a document server communicatively coupled to at least one client computing device, a document comprising an operation log, wherein the operation log comprises at least one first sequential operation defining operations to create data values of the document, a document object model, wherein the document is at least partially positioned on at least one of the document server and a first client computing device of the at least one client computing device, and a formula engine, wherein the formula engine is structured to determine a calculation definition in response to the user formula value and the document object model.

Abstract: This invention relates to extracellular vesicles and method of isolated tissue-specific extracellular vesicles from bodily fluids. The invention further relates to methods of using extracellular vesicles for diagnostic applications for detecting and monitoring diseases, conditions, and damage in a subject. The invention also relates to methods of using extracellular vesicles for therapeutic applications for treating diseases, conditions, and damage in a subject.

Abstract: The present disclosure describes methods and systems for interpreting a table grouping input value associated with a table, wherein the table comprises a plurality of categories and a plurality of associated data sets corresponding to the plurality of categories, determining an aggregation value in response to the table grouping input value, wherein the aggregation value corresponds to at least one of the plurality of categories, and in response to the aggregation value, providing an aggregated table view.

Abstract: The present disclosure describes methods and systems for interpreting a first user input comprising a text flow entry, interpreting a second user input comprising one of an in-line data access entry and a table-based calculation entry, positioning a text entry value on a unified document surface in response to the first user input, creating at least one data structure in response to the one of the in-line data access entry and the table-based calculation entry, and positioning the data structure on the unified document surface.

Abstract: The present disclosure describes methods and systems for a document server communicatively coupled to at least one client computing device, a document comprising an operation log, wherein the operation log comprises at least one first sequential operation defining operations to create data values of the document, a document object model, wherein the document is at least partially positioned on at least one of the document server and a first client computing device of the at least one client computing device, and a formula engine, wherein the formula engine is structured to determine a calculation definition in response to the user formula value and the document object model.

Abstract: The present invention discloses receiving a first operation log from a first computing device, creating a first document view in response to the first operation log, the document view comprising content generated using at least a portion of the first operation log, providing the first document view to a display device, receiving a user document change input value, and creating a local operation log in response to the first operation log and the user document change input value, the local operation log comprising at least one sequential operation defining operations to create a second document, updating the first document view in response to the user document change input value, and communicating a change value for the first operation log to the first computing device in response to the first operation log and the local operation log.

Abstract: The present disclosure describes methods and systems for interpreting a table grouping input value associated with a table, wherein the table comprises a plurality of categories and a plurality of associated data sets corresponding to the plurality of categories, determining an aggregation value in response to the table grouping input value, wherein the aggregation value corresponds to at least one of the plurality of categories, and in response to the aggregation value, providing an aggregated table view.

Abstract: The present disclosure describes methods and systems for interpreting a first user input comprising a text flow entry, interpreting a second user input comprising one of an in-line data access entry and a table-based calculation entry, positioning a text entry value on a unified document surface in response to the first user input, creating at least one data structure in response to the one of the in-line data access entry and the table-based calculation entry, and positioning the data structure on the unified document surface.

Abstract: The present disclosure describes methods and systems for a document server communicatively coupled to at least one client computing device, a document comprising an operation log, wherein the operation log comprises at least one first sequential operation defining operations to create data values of the document, a document object model, wherein the document is at least partially positioned on at least one of the document server and a first client computing device of the at least one client computing device, and a formula engine, wherein the formula engine is structured to determine a calculation definition in response to the user formula value and the document object model.

Abstract: The present disclosure describes methods and systems for a document server communicatively coupled to at least one client computing device, a document comprising an operation log, wherein the operation log comprises at least one first sequential operation defining operations to create data values of the document, a document object model, wherein the document is at least partially positioned on at least one of the document server and a first client computing device of the at least one client computing device, and a formula engine, wherein the formula engine is structured to determine a calculation definition in response to the user formula value and the document object model.

Abstract: The present invention discloses receiving a first operation log from a first computing device, creating a first document view in response to the first operation log, the document view comprising content generated using at least a portion of the first operation log, providing the first document view to a display device, receiving a user document change input value, and creating a local operation log in response to the first operation log and the user document change input value, the local operation log comprising at least one sequential operation defining operations to create a second document, updating the first document view in response to the user document change input value, and communicating a change value for the first operation log to the first computing device in response to the first operation log and the local operation log.

Abstract: The present disclosure describes methods and systems for interpreting a first user input comprising a text flow entry, interpreting a second user input comprising one of an in-line data access entry and a table-based calculation entry, positioning a text entry value on a unified document surface in response to the first user input, creating at least one data structure in response to the one of the in-line data access entry and the table-based calculation entry, and positioning the data structure on the unified document surface.

Abstract: The present disclosure describes methods and systems for interpreting a first user input comprising a text flow entry, interpreting a second user input comprising one of an in-line data access entry and a table-based calculation entry, positioning a text entry value on a unified document surface in response to the first user input, creating at least one data structure in response to the one of the in-line data access entry and the table-based calculation entry, and positioning the data structure on the unified document surface.

Abstract: The present disclosure describes methods and systems for a document server communicatively coupled to at least one client computing device, a document comprising an operation log, wherein the operation log comprises at least one first sequential operation defining operations to create data values of the document, a document object model, wherein the document is at least partially positioned on at least one of the document server and a first client computing device of the at least one client computing device, and a formula engine, wherein the formula engine is structured to determine a calculation definition in response to the user formula value and the document object model.

Abstract: The present invention discloses receiving a first operation log from a first computing device, creating a first document view in response to the first operation log, the document view comprising content generated using at least a portion of the first operation log, providing the first document view to a display device, receiving a user document change input value, and creating a local operation log in response to the first operation log and the user document change input value, the local operation log comprising at least one sequential operation defining operations to create a second document, updating the first document view in response to the user document change input value, and communicating a change value for the first operation log to the first computing device in response to the first operation log and the local operation log.