Patents by Inventor Matthew Brenner

Matthew Brenner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210213031
    Abstract: Methods and compositions for treating cyanide, sulfide, or methane-thiol exposure in a subject. The compositions may include one or more cobinamide compounds, such as an amino-tetrazole-cobinamide and/or a di-(amino-tetrazole)-cobinamide.
    Type: Application
    Filed: June 4, 2019
    Publication date: July 15, 2021
    Applicants: The Regents of the University of California, The Regents of the university of Colorado
    Inventors: Gerard Boss, Adriano Chan, Matthew Brenner, Sari Brenner Mahon, Vikhyat Bebarta
  • Patent number: 10458921
    Abstract: The invention includes an improvement in a method of assessing a gemstone having at least one planar face with an internally reflecting surface including the steps of optically modifying the at least one planar face of the gemstone to return a sample beam from an internally reflecting plane corresponding to the at least one planar face to an optical coherence tomography (OCT) system; selectively directing the sample beam from an optical coherence tomography (OCT) system onto the gemstone; and generating an OCT image map of the gemstone to determine volume, gem carat weight and/or quality.
    Type: Grant
    Filed: December 19, 2016
    Date of Patent: October 29, 2019
    Assignee: The Regents of the University of California
    Inventors: Matthew Brenner, Andrew Emon Heidari, Zhongping Chen, Sari Mahon, Joseph Jing
  • Publication number: 20180372647
    Abstract: The invention includes an improvement in a method of assessing a gemstone having at least one planar face with an internally reflecting surface including the steps of optically modifying the at least one planar face of the gemstone to return a sample beam from an internally reflecting plane corresponding to the at least one planar face to an optical coherence tomography (OCT) system; selectively directing the sample beam from an optical coherence tomography (OCT) system onto the gemstone; and generating an OCT image map of the gemstone to determine volume, gem carat weight and/or quality.
    Type: Application
    Filed: December 19, 2016
    Publication date: December 27, 2018
    Inventors: Matthew Brenner, Andrew Emon Heidari, Zhongping Chen, Sari Mahon, Joseph Jing
  • Patent number: 9534007
    Abstract: A composition and method for treating excess cyanide and hydrogen sulfide comprising administering a cobinamide. Further a method for determining extent of binding by an agent to an extracellular matrix.
    Type: Grant
    Filed: December 23, 2013
    Date of Patent: January 3, 2017
    Assignees: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE UNITED STATES OF AMERICA as represented by THE SECRETARY OF THE AIR FORCE
    Inventors: Gerry Boss, Adriano Chan, Matthew Brenner, Sari Brenner-Mahon, Vikhyat S. Bebarta, Jingjing Jiang, Karen Christman, Jean Wang Wassenaar
  • Publication number: 20150367149
    Abstract: This disclosure concerns materials for detecting and removing gaseous chemical agents (e.g., cyanide, cyanogen, sulfide, nitrite, nitric oxide, and combinations thereof), devices including the materials, and methods of making and using the disclosed materials. Embodiments of the disclosed materials include a support material impregnated with cobinamide and/or a cobinamide derivative.
    Type: Application
    Filed: June 23, 2015
    Publication date: December 24, 2015
    Inventors: Lee A. Greenawald, Gerry R. Boss, Nicole Fry, Michael J. Sailor, Matthew Brenner, Sari B. Mahon
  • Publication number: 20150353590
    Abstract: A composition and method for treating excess cyanide and hydrogen sulfide comprising administering a cobinamide. Further a method for determining extent of binding by an agent to an extracellular matrix.
    Type: Application
    Filed: December 23, 2013
    Publication date: December 10, 2015
    Inventors: Gerry Boss, Adriano Chan, Matthew Brenner, Sari Brenner-Mahon, Vikhyat S. Bebarta, Jingjing Jiang, Karen Christman, Jean Wang
  • Patent number: 8741658
    Abstract: A method and devices analyze for the presence of cyanide in samples using colorimetric analysis of samples after contacting with cobinamide or monocyanocohinapmide.
    Type: Grant
    Filed: March 15, 2011
    Date of Patent: June 3, 2014
    Assignees: The Regents of the University of California, Board of Regents, The University of Texas System
    Inventors: Gerry Boss, Vijay Sharma, Matthew Brenner, Purnendu K. Dasgupta, William Curt Blackledge
  • Publication number: 20130005044
    Abstract: A method and devices analyze for the presence of cyanide in samples using colorimetric analysis of samples after contacting with cobinamide or monocyanocohinapmide.
    Type: Application
    Filed: March 15, 2011
    Publication date: January 3, 2013
    Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Gerry Boss, Vijay Sharma, Matthew Brenner, Pernendu K. Dasgupta, William Curt Blackledge
  • Patent number: 8285368
    Abstract: An endoscopic swept-source Fourier Domain optical coherence tomographic system (FDOCT system) for imaging of tissue structure includes a Fourier Domain mode locked (FDML), high speed, narrow line-width, wavelength swept source, an OCT interferometer having a sample arm, a reference arm, a detection arm, and a source arm coupled to the swept source, an endoscopic probe coupled to the sample arm, and a data processing circuit coupled to the detection arm. The swept source includes a long optic fiber functioning as a cavity, a high optical gain lasing module, and a tunable narrow bandwidth bandpass filter for wavelength selection combined to form a unidirectional ring laser cavity, where the tunable narrow bandwidth bandpass filter is driven synchronously with the optical round-trip time of a propagating light wave in the cavity.
    Type: Grant
    Filed: July 9, 2010
    Date of Patent: October 9, 2012
    Assignee: The Regents of the University of California
    Inventors: Zhongping Chen, Jun Zhang, Matthew Brenner
  • Publication number: 20110009752
    Abstract: An endoscopic swept-source Fourier Domain optical coherence tomographic system (FDOCT system) for imaging of tissue structure includes a Fourier Domain mode locked (FDML), high speed, narrow line-width, wavelength swept source, an OCT interferometer having a sample arm, a reference arm, a detection arm, and a source arm coupled to the swept source, an endoscopic probe coupled to the sample arm, and a data processing circuit coupled to the detection arm. The swept source includes a long optic fiber functioning as a cavity, a high optical gain lasing module, and a tunable narrow bandwidth bandpass filter for wavelength selection combined to form a unidirectional ring laser cavity, where the tunable narrow bandwidth bandpass filter is driven synchronously with the optical round-trip time of a propagating light wave in the cavity.
    Type: Application
    Filed: July 9, 2010
    Publication date: January 13, 2011
    Applicant: The Regents of the University of California
    Inventors: Zhongping Chen, Jun Zhang, Matthew Brenner
  • Patent number: 7576865
    Abstract: A fiber-optic bundle based optical coherence tomography (OCT) probe method is demonstrated in a multimode optical fiber bundle based OCT system. The system can achieve a lateral resolution of 12 ?m and an axial resolution of 10 ?m using a super-luminescent diode source. This imaging approach eliminates any moving parts in the probe and has a primary advantage for use in extremely compact and safe OCT endoscopes to image internal organs and great potential to be combined with confocal endoscopic microscopy.
    Type: Grant
    Filed: April 17, 2006
    Date of Patent: August 18, 2009
    Inventors: Zhongping Chen, Tuqiang Xie, David Mukai, Matthew Brenner
  • Publication number: 20080134942
    Abstract: Carbon nanotubes (CNTs) are combined with cement, aggregate and plasticizers to form composites with increased strength. CNT reinforced concretes comprising cement, plasticizer, aggregate, and nanotubes, hydrated with water are disclosed. A mixture of CNTs, cement, and plasticizer can be prepared for later admixture with aggregates and water to form composites having improved strength characteristics. A method for increasing the strength of concrete comprising the steps of admixing CNTs and plasticizer's with cement, aggregate, and water for hydration is also disclosed.
    Type: Application
    Filed: December 12, 2006
    Publication date: June 12, 2008
    Inventors: Matthew Brenner, Arjun Mariputtana Kavi, Michael Guan-Yu Li
  • Patent number: 7248909
    Abstract: A device and method utilizes a broadband diffuse optical spectroscopy (DOS) system to dynamically calculate the concentrations of multiple chromophores in vivo using a non-invasive probe. The device and method permit dynamic monitoring of multiple in vivo tissue chromophores non-invasively with sensitivities necessary for effective therapeutic monitoring. The device includes a probe containing first and second source optical fibers as well as first and second detector optical fibers. The probe is placed adjacent to a sample of interest and detects reflected light which is passed to a proximally located detector and spectrometer. The concentrations of multiple chromophores are determined in real time. In a preferred embodiment, the multiple tissue chromophores include at least two of methemoglobin (MetHb), deoxyhemoglobin (Hb-R), oxyhemoglobin (Hb-O2), water (H2O), and methylene blue (MB).
    Type: Grant
    Filed: April 12, 2005
    Date of Patent: July 24, 2007
    Assignee: The Regents of the University of California
    Inventors: Jangwoen Lee, Bruce J. Tromberg, Albert E. Cerussi, Matthew Brenner
  • Publication number: 20070038119
    Abstract: A fiber-optic bundle based optical coherence tomography (OCT) probe method is demonstrated in a multimode optical fiber bundle based OCT system. The system can achieve a lateral resolution of 12 ?m and an axial resolution of 10 ?m using a super-luminescent diode source. This imaging approach eliminates any moving parts in the probe and has a primary advantage for use in extremely compact and safe OCT endoscopes to image internal organs and great potential to be combined with confocal endoscopic microscopy.
    Type: Application
    Filed: April 17, 2006
    Publication date: February 15, 2007
    Inventors: Zhongping Chen, Tuqiang Xie, David Mukai, Matthew Brenner
  • Publication number: 20050228246
    Abstract: A device and method utilizes a broadband diffuse optical spectroscopy (DOS) system to dynamically calculate the concentrations of multiple chromophores in vivo using a non-invasive probe. The device and method permit dynamic monitoring of multiple in vivo tissue chromophores non-invasively with sensitivities necessary for effective therapeutic monitoring. The device includes a probe containing first and second source optical fibers as well as first and second detector optical fibers. The probe is placed adjacent to a sample of interest and detects reflected light which is passed to a proximally located detector and spectrometer. The concentrations of multiple chromophores are determined in real time. In a preferred embodiment, the multiple tissue chromophores include at least two of methemoglobin (MetHb), deoxyhemoglobin (Hb-R), oxyhemoglobin (Hb-O2), water (H2O), and methylene blue (MB).
    Type: Application
    Filed: April 12, 2005
    Publication date: October 13, 2005
    Inventors: Jangwoen Lee, Bruce Tromberg, Albert Cerussi, Matthew Brenner