Abstract: An active magnetic shield system, including an array of magnetic field sensors arranged to sense a local magnetic field. An array of magnetic field elements are arranged produce a magnetic field. Each magnetic field element has a unit coil for mounting to a plurality of surfaces arranged in at least 3 planes to define an enclosed cancellation volume, and to produce a vector magnetic field pattern.

Abstract: Antibody-drug conjugates that bind to human oncology targets are disclosed. The antibody-drug conjugates comprise a Bcl-xL inhibitor drug moiety. The disclosure farther relates to methods and compositions for use in the treatment of cancers by administering the antibody-drug conjugates provided herein. Linker-drug conjugates comprising Bcl-xL inhibitor drug moiety and methods of making same are also disclosed.

Abstract: Described herein are 3-fluoro-4-hydroxybenzamide-containing inhibitors and/or degraders, and pharmaceutical compositions containing 3-fluoro-hydroxybenzamide-containing inhibitors and/or degraders. In some embodiments, the 3-fluoro-4-hydroxybenzamide-containing compounds of the disclosure can be used to treat a condition, for example, nonalcoholic fatty liver disease and nonalcoholic steatohepatitis.

Abstract: There is provided an assembly for a turbocharger, the assembly comprising a turbine housing and a nozzle ring, wherein one of the turbine housing and the nozzle ring comprises a tongue and the other of the turbine housing and the nozzle ring comprises a corresponding slot, the tongue and slot being configured to engage and prevent relative rotation of the turbine housing and the nozzle ring. Also provided is a method of manufacturing a turbine housing, assembly for use in a turbocharger, or a turbocharger.

Abstract: A method of reducing error in magnetoencephalography arising from the presence of a non-neuromagnetic field. The method comprises measuring, using a sensor array for measuring neuromagnetic fields, magnetic field at a plurality of discrete locations around a subject's head to provide sensor data; wherein the magnetic field measured at at least some of the locations includes a neuromagnetic field from a source of interest within a subject's brain and a non-neuromagnetic field from a source of no interest external to the brain. The measuring comprises: measuring, at at least a first subset of the locations, a magnetic field along a first direction relative to a radial axis intersecting the respective location, and measuring, at at least a second subset of the locations, a magnetic field along a second direction relative to a radial axis intersecting the respective location which is different to the first direction; and performing source reconstruction using the sensor data.

Abstract: There is provided an assembly for a turbocharger, the assembly comprising a turbine housing and a nozzle ring, wherein one of the turbine housing and the nozzle ring comprises a tongue and the other of the turbine housing and the nozzle ring comprises a corresponding slot, the tongue and slot being configured to engage and prevent relative rotation of the turbine housing and the nozzle ring. Also provided is a method of manufacturing a turbine housing, assembly for use in a turbocharger, or a turbocharger.

Abstract: A rotary turbine bypass valve comprises a valve chamber and a valve rotor. The chamber is positioned at a junction of an inlet port, an outlet port and a bypass port. The inlet port is configured to receive exhaust gas, the outlet port is configured to fluidly communicate with a turbine inlet, and the bypass port is configured to fluidly communicate with an exhaust aftertreatment device. The rotor comprises a first and second recess, the first recess defining a primary flow passage, the second recess defining a secondary flow passage. The rotor is rotatable between a first position in which the rotor substantially blocks exhaust gas flow through the bypass port and a second position in which the rotor permits such. The secondary flow passage is configured to selectively permit fluid communication between the inlet port and the bypass port when the primary flow passage is partially blocked.

Abstract: A method of designing a magnetic shield comprising a structure enclosing a space, the structure comprising passive magnetic shielding material and a winding configured to produce a specified magnetic within the structure when current is passed through the winding, is disclosed. The method comprises determining an optimised configuration of the winding accounting for the presence of the passive magnetic shield material by implementing one or more boundary conditions at the surface of the passive magnetic shielding material.

Abstract: A structural joint for a pickup truck, according to an exemplary aspect of the present disclosure includes, among other things, a C-pillar, a gusset bracket, a cab back bracket, and a box panel. The C-pillar, gusset bracket, cab back bracket, and box panel are directly welded to each other to provide an assembly having a box section.

Abstract: A structural joint for a pickup truck, according to an exemplary aspect of the present disclosure includes, among other things, a C-pillar, a gusset bracket, a cab back bracket, and a box panel. The C-pillar, gusset bracket, cab back bracket, and box panel are directly welded to each other to provide an assembly having a box section.

Abstract: A rotary turbine bypass valve comprises a valve chamber and a valve rotor. The chamber is positioned at a junction of an inlet port, an outlet port and a bypass port. The inlet port is configured to receive exhaust gas, the outlet port is configured to fluidly communicate with a turbine inlet, and the bypass port is configured to fluidly communicate with an exhaust aftertreatment device. The rotor comprises a first and second recess, the first recess defining a primary flow passage, the second recess defining a secondary flow passage. The rotor is rotatable between a first position in which the rotor substantially blocks exhaust gas flow through the bypass port and a second position in which the rotor permits such. The secondary flow passage is configured to selectively permit fluid communication between the inlet port and the bypass port when the primary flow passage is partially blocked.

Abstract: A vehicle includes a hood that is rotatably secured to a vehicle body. The hood has an upper panel, a lower panel, and a reinforcement member disposed therebetween. The reinforcement member has a baseplate and a tab. The baseplate is secured to an internal surface of the lower panel. The tab has a proximal end that is secured to the baseplate and a distal end that extends away from the baseplate and is secured to an internal surface of the upper panel.

Abstract: The present invention provides devices and methods for the impregnation of air with the vapor or aerosol of a substance in a ‘controllable manner to enable the testing or training of detection means to evaluate and quantify the presence of the substance in an enclosed volume, and i?• particular to enable production of training aids and quality assurance test items for use in canine-olfaction based security screening.

Abstract: Methods and systems for creating mobile conference rooms for conference calls between client devices and one or more contacts are described herein. A server receives, from the client device, a request to create a mobile conference room. The server creates the mobile conference room by assigning a phone number to the mobile conference room. After notifying the client device, the server receives data regarding one or more contacts to add to the mobile conference room. The server receives, from the client device, a request to initiate a conference call with a subset of contacts. A call is received, from the server, concurrently by each of the subset of contacts. The server bridges the client device and the contacts that have answered the call on the conference call.

Abstract: A current transformer is described which comprises a housing having one or more apertures, each for receiving a primary cable or busbar, one or more magnetic cores enclosed within the housing and being positioned proximate to respective ones of the apertures so that a magnetic field is produced in a magnetic core when a primary current flows through a primary cable or busbar received through the respective aperture, and one or more secondary windings enclosed within the housing, each secondary winding being wrapped around at least a portion of a respective magnetic core so that a secondary current is induced in a secondary winding when a magnetic field is produced in the respective magnetic core. Shunt circuitry is enclosed within the housing and is connected across the secondary windings to generate a respective voltage signal for each secondary winding. A connector socket is integrally mounted to the housing for outputting the voltage signals.

Abstract: Methods and systems for creating mobile conference rooms for conference calls between client devices and one or more contacts are described herein. A server receives, from the client device, a request to create a mobile conference room. The server creates the mobile conference room by assigning a phone number to the mobile conference room. After notifying the client device, the server receives data regarding one or more contacts to add to the mobile conference room. The server receives, from the client device, a request to initiate a conference call with a subset of contacts. A call is received, from the server, concurrently by each of the subset of contacts. The server bridges the client device and the contacts that have answered the call on the conference call.

Abstract: The present invention provides devices and methods for the impregnation of air with the vapour or aerosol of a substance in a ‘controllable manner to enable the testing or training of detection means to evaluate and quantify the presence of the substance in an enclosed volume, and i?• particular to enable production of training aids and quality assurance test items for use in canine-olfaction based security screening.

Abstract: A current transformer is described which comprises a housing having one or more apertures, each for receiving a primary cable or busbar, one or more magnetic cores enclosed within the housing and being positioned proximate to respective ones of the apertures so that a magnetic field is produced in a magnetic core when a primary current flows through a primary cable or busbar received through the respective aperture, and one or more secondary windings enclosed within the housing, each secondary winding being wrapped around at least a portion of a respective magnetic core so that a secondary current is induced in a secondary winding when a magnetic field is produced in the respective magnetic core. Shunt circuitry is enclosed within the housing and is connected across the secondary windings to generate a respective voltage signal for each secondary winding. A connector socket is integrally mounted to the housing for outputting the voltage signals.