Patents by Inventor Matthew C. Evans
Matthew C. Evans has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 12173369Abstract: Embodiments of the invention include systems, apparatus, and methods for detecting copy number variation (CNV) in the genomes of one or more patients. Samples of DNA may be taken from several patients, and then sections of the patients' DNA may be sequenced, e.g., through a process that may include, for each patient, one or more of: purifying, concentrating, fragmenting, labeling, filtering, and amplifying that patient's DNA. Fragments from several patients may be pooled, and the fragments in the pool may be sequenced. The sequencing data is then subjected to analysis, which includes several normalization steps. The normalized data are then examined to identify CNV, which is reported.Type: GrantFiled: April 1, 2020Date of Patent: December 24, 2024Assignee: QUEST DIAGNOSTICS INVESTMENTS INCORPORATEDInventors: Corey Brastaad, Christopher D. Elzinga, Mingsheng Zhang, Matthew C. Evans
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Publication number: 20240152210Abstract: An electronic device, while displaying a representation of a piece of music, detects a first input event at a location corresponding to the representation of the piece of music, and in response, provides tactile feedback that corresponds to at least a subset of beats of the piece of music. Subsequently, in response to detecting a second input event at the location corresponding to the representation of the piece of music, the electronic device ceases to provide the tactile feedback that corresponds to the beats of the piece of music.Type: ApplicationFiled: January 16, 2024Publication date: May 9, 2024Inventors: May-Li Khoe, Jeffrey Traer Bernstein, Avi E. Cieplinski, Bianca C. Costanzo, Rachel A. Roth, Matthew C. Evans, Samuel M. Roberts
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Publication number: 20200270682Abstract: Embodiments of the invention include systems, apparatus, and methods for detecting copy number variation (CNV) in the genomes of one or more patients. Samples of DNA may be taken from several patients, and then sections of the patients' DNA may be sequenced, e.g., through a process that may include, for each patient, one or more of: purifying, concentrating, fragmenting, labeling, filtering, and amplifying that patient's DNA. Fragments from several patients may be pooled, and the fragments in the pool may be sequenced. The sequencing data is then subjected to analysis, which includes several normalization steps. The normalized data are then examined to identify CNV, which is reported.Type: ApplicationFiled: April 1, 2020Publication date: August 27, 2020Applicant: QUEST DIAGNOSTICS INVESTMENTS INCORPORATEDInventors: Corey Brastaad, Christopher D. Elzinga, Mingsheng Zhang, Matthew C. Evans
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Patent number: 10640823Abstract: Embodiments of the invention include systems, apparatus, and methods for detecting copy number variation (CNV) in the genomes of one or more patients. Samples of DNA may be taken from several patients, and then sections of the patients' DNA may be sequenced, e.g., through a process that may include, for each patient, one or more of: purifying, concentrating, fragmenting, labeling, filtering, and amplifying that patient's DNA. Fragments from several patients may be pooled, and the fragments in the pool may be sequenced. The sequencing data is then subjected to analysis, which includes several normalization steps. The normalized data are then examined to identify CNV, which is reported.Type: GrantFiled: July 8, 2015Date of Patent: May 5, 2020Assignee: QUEST DIAGNOSTICS INVESTMENTS INCORPORATEDInventors: Corey Brastaad, Christopher D. Elzinga, Mingsheng Zhang, Matthew C. Evans
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Publication number: 20170009287Abstract: Embodiments of the invention include systems, apparatus, and methods for detecting copy number variation (CNV) in the genomes of one or more patients. Samples of DNA may be taken from several patients, and then sections of the patients' DNA may be sequenced, e.g., through a process that may include, for each patient, one or more of: purifying, concentrating, fragmenting, labeling, filtering, and amplifying that patient's DNA. Fragments from several patients may be pooled, and the fragments in the pool may be sequenced. The sequencing data is then subjected to analysis, which includes several normalization steps. The normalized data are then examined to identify CNV, which is reported.Type: ApplicationFiled: July 8, 2015Publication date: January 12, 2017Applicant: Quest Diagnostics investments IncorporatedInventors: Corey Brastaad, Christopher D. Elzinga, Mingsheng Zhang, Matthew C. Evans
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Patent number: 9206978Abstract: A steam generator system for a pressurized water reactor which employs an external to containment steam drum and recirculation loop piping. The steam generator system changes the arrangement of a typical pressurized water reactor recirculation steam generator by relocating the functions of steam separation and feedwater preheating outside of the reactor coolant system. The steam generator system and thermal hydraulic conditions are selected in order to minimize the size of the steam generator heat exchanger component volume inside of the containment. The external steam drum component can be isolated in accident conditions when desired and is used as a source of secondary fluid inventory for improved decay heat removal capability and tolerance for loss of feedwater events. Thus, the steam generator component volume inside of the containment is reduced and the amount of maintenance required for the reactor coolant system components are similarly reduced.Type: GrantFiled: June 13, 2012Date of Patent: December 8, 2015Assignee: Westinghouse Electric Company LLCInventors: Matthew C. Evans, Alexander W. Harkness, Creed Taylor, William Edward Cummins
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Publication number: 20130336442Abstract: A steam generator system for a pressurized water reactor which employs an external to containment steam drum and recirculation loop piping. The steam generator system changes the arrangement of a typical pressurized water reactor recirculation steam generator by relocating the functions of steam separation and feedwater preheating outside of the reactor coolant system. The steam generator system and thermal hydraulic conditions are selected in order to minimize the size of the steam generator heat exchanger component volume inside of the containment. The external steam drum component can be isolated in accident conditions when desired and is used as a source of secondary fluid inventory for improved decay heat removal capability and tolerance for loss of feedwater events. Thus, the steam generator component volume inside of the containment is reduced and the amount of maintenance required for the reactor coolant system components are similarly reduced.Type: ApplicationFiled: June 13, 2012Publication date: December 19, 2013Applicant: WESTINGHOUSE ELECTRIC COMPANY LLCInventors: Matthew C. Evans, Alexander W. Harkness, Creed Taylor, William Edward Cummins
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Publication number: 20100162878Abstract: A song audio is played and a graphical representation of a musical instrument contributing to the audio is displayed. A fingering display is overlayed on the graphical representation of the instrument during the playing of song. The fingering display is synchronized to the song audio. During the playing of the song audio, the tempo of the song is adjusted. The pitch of the song is substantially preserved in real-time despite the tempo adjustment. In addition, the synchronization between the fingering display and the audio are maintained in real-time in view of the adjusted tempo.Type: ApplicationFiled: December 31, 2008Publication date: July 1, 2010Applicant: Apple Inc.Inventors: Gerhard H. Lengeling, Alexander Soren, Jan-Hinnerk Helms, Alexander H. Little, John Danty, Matthew C. Evans, Timothy B. Martin, Ole Lagemann, Stefan Pillhofer