Patents by Inventor Matthew C. Franklin

Matthew C. Franklin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTI-HUMAN PAPILLOMAVIRUS (HPV) ANTIGEN-BINDING PROTEINS AND METHODS OF USE THEREOF
    Publication number: 20230270837
    Abstract: The present invention provides antigen-binding proteins that specifically bind to an HLA-displayed human papillomavirus (HPV) peptide, and therapeutic and diagnostic methods of using those binding proteins.
    Type: Application
    Filed: December 15, 2022
    Publication date: August 31, 2023
    Inventors: Kevin A. Bray, Frank Delfino, Matthew C. Franklin, Elena S. Garnova, Jessica Kirshner, Douglas MacDonald, William Olson, Gavin Thurston
  • Anti-human papillomavirus (HPV) antigen-binding proteins and methods of use thereof
    Patent number: 11559576
    Abstract: The present invention provides antigen-binding proteins that specifically bind to an HLA-displayed human papillomavirus (HPV) peptide, and therapeutic and diagnostic methods of using those binding proteins.
    Type: Grant
    Filed: August 13, 2020
    Date of Patent: January 24, 2023
    Assignee: Regeneran Pharmaceuticals, Inc.
    Inventors: Kevin A. Bray, Frank Delfino, Matthew C. Franklin, Elena S. Garnova, Jessica Kirshner, Douglas MacDonald, William Olson, Gavin Thurston
  • ANTI-NEW YORK ESOPHAGEAL SQUAMOUS CELL CARCINOMA 1 (NY-ESO-1) ANTIGEN-BINDING PROTEINS AND METHODS OF USE THEREOF
    Publication number: 20220251215
    Abstract: The present disclosure provides antigen-binding proteins that specifically bind to an H LA-displayed New York esophageal squamous cell carcinoma 1 (NY-ESO-1) peptide, and therapeutic and diagnostic methods of using those binding proteins. The antigen-binding proteins of the present disclosure bind with a high degree of specificity to HLA-displayed NY-ESO-1 and do not bind to HLA-displayed peptides that differ by 2, 3, 4, 5 or more amino acids.
    Type: Application
    Filed: July 2, 2020
    Publication date: August 11, 2022
    Inventors: Kevin A. Bray, Frank Delfino, David Dilillo, Matthew C. Franklin, Jessica Kirshner, Douglas MacDonald
  • ANTI-HUMAN PAPILLOMAVIRUS (HPV) ANTIGEN-BINDING PROTEINS AND METHODS OF USE THEREOF
    Publication number: 20220001000
    Abstract: The present invention provides antigen-binding proteins that specifically bind to an HLA-displayed human papillomavirus (HPV) peptide, and therapeutic and diagnostic methods of using those binding proteins.
    Type: Application
    Filed: August 13, 2020
    Publication date: January 6, 2022
    Inventors: Kevin A. Bray, Frank Delfino, Matthew C. Franklin, Elena S. Garnova, Jessica Kirshner, Douglas MacDonald, William Olson, Gavin Thurston
  • Anti-human papillomavirus (HPV) antigen-binding proteins and methods of use thereof
    Patent number: 10806780
    Abstract: The present invention provides antigen-binding proteins that specifically bind to an HLA-displayed human papillomavirus (HPV) peptide, and therapeutic and diagnostic methods of using those binding proteins.
    Type: Grant
    Filed: June 27, 2018
    Date of Patent: October 20, 2020
    Assignee: Regeneron Pharmaceuticals, Inc.
    Inventors: Kevin A. Bray, Frank Delfino, Matthew C. Franklin, Elena S. Garnova, Jessica R. Kirshner, Douglas MacDonald, William Olson, Gavin Thurston
  • ANTI-HUMAN PAPILLOMAVIRUS (HPV) ANTIGEN-BINDING PROTEINS AND METHODS OF USE THEREOF
    Publication number: 20190000956
    Abstract: The present invention provides antigen-binding proteins that specifically bind to an HLA-displayed human papillomavirus (HPV) peptide, and therapeutic and diagnostic methods of using those binding proteins.
    Type: Application
    Filed: June 27, 2018
    Publication date: January 3, 2019
    Inventors: Kevin A. Bray, Frank Delfino, Matthew C. Franklin, Elena S. Garnova, Jessica R. Kirshner, Douglas MacDonald, William Olson, Gavin Thurston
  • COMPOSITIONS AND METHODS FOR ENHANCING APOPTOSIS
    Publication number: 20120058953
    Abstract: The present invention is directed to compositions of matter useful for the enhancement of apoptosis in mammals and to methods of using those compositions of matter for the same.
    Type: Application
    Filed: October 14, 2011
    Publication date: March 8, 2012
    Applicant: Genentech, Inc.
    Inventors: Kurt Deshayes, Wayne Fairbrother, John Flygare, Matthew C. Franklin, Saloumeh Fischer, Domagoj Vucic
  • COMPOSITIONS AND METHODS FOR ENHANCING APOPTOSIS
    Publication number: 20110039324
    Abstract: The present invention is directed to compositions of matter useful for the enhancement of apoptosis in mammals and to methods of using those compositions of matter for the same.
    Type: Application
    Filed: July 13, 2010
    Publication date: February 17, 2011
    Applicant: Genentech, Inc.
    Inventors: Kurt Deshayes, Wayne Fairbrother, John Flygare, Matthew C. Franklin, Saloumeh Fischer, Domagoj Vucic
  • Compositions and methods for enhancing apoptosis
    Publication number: 20090148921
    Abstract: The present invention is directed to compositions of matter useful for the enhancement of apoptosis in mammals and to methods of using those compositions of matter for the same.
    Type: Application
    Filed: September 14, 2006
    Publication date: June 11, 2009
    Applicant: Genentech, Inc.
    Inventors: Kurt Deshayes, Wayne Fairbrother, John Flygare, Matthew C. Franklin, Saloumeh Fischer, Domagoj Vucic
  • Compositions and methods for the screening pro-apoptotic compounds
    Patent number: 7067274
    Abstract: The present invention is directed to compositions of matter useful for the enhancement of apoptosis in mammals and to methods of using those compositions of matter for the same.
    Type: Grant
    Filed: November 8, 2004
    Date of Patent: June 27, 2006
    Assignees: Genentech, Inc., The Burnham Institute
    Inventors: Wayne J. Fairbrother, Matthew C. Franklin, Heidi Jenii Ackerly Wallweber, Linda Orren Elliott, Saloumeh Kadkhodayan, Domagoj Vucic, Guy Salvesen
  • Compositions and methods for enhancing apoptosis
    Publication number: 20040171554
    Abstract: The present invention is directed to compositions of matter useful for the enhancement of apoptosis in mammals and to methods of using those compositions of matter for the same.
    Type: Application
    Filed: February 7, 2003
    Publication date: September 2, 2004
    Applicant: GENENTECH, INC.
    Inventors: Kurt Deshayes, Wayne Fairbrother, John Flygare, Matthew C. Franklin, Saloumeh Fischer, Domagoj Vucic