Patents by Inventor Matthew C. L. Keith

Matthew C. L. Keith has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cardiac progenitor cells and methods of use therefor
    Patent number: 9987310
    Abstract: Provided are pharmaceutical compositions that include a pharmaceutically acceptable carrier and isolated post-natal cardiac progenitor cells (CPCs) and/or progeny cells thereof that are SSEA3-positive and c-kit-negative. Also provided are methods for preparing cells capable of repairing damaged myocardium, methods for isolating populations of SSEA3-positive/c-kit-negative CPCs from cardiac tissue samples, methods for preparing an isolated cell population enriched in post-natal SSEA3-positive/c-kit-negative CPCs, therapeutic methods for using the presently disclosed cells and populations of cells to treat subjects in need thereof, and cell cultures that contain the presently disclosed cells and populations of cells.
    Type: Grant
    Filed: November 25, 2014
    Date of Patent: June 5, 2018
    Assignee: University of Louisville Research Foundation, Inc.
    Inventors: Matthew C. L. Keith, Marcin Wysoczynski, Roberto Bolli
  • CARDIAC PROGENITOR CELLS AND METHODS OF USE THEREFOR
    Publication number: 20170239298
    Abstract: Provided are pharmaceutical compositions that include a pharmaceutically acceptable carrier and isolated post-natal cardiac progenitor cells (CPCs) and/or progeny cells thereof that are SSEA3-positive and c-kit-negative. Also provided are methods for preparing cells capable of repairing damaged myocardium, methods for isolating populations of SSEA3-positive/c-kit-negative CPCs from cardiac tissue samples, methods for preparing an isolated cell population enriched in post-natal SSEA3-positive/c-kit-negative CPCs, therapeutic methods for using the presently disclosed cells and populations of cells to treat subjects in need thereof, and cell cultures that contain the presently disclosed cells and populations of cells.
    Type: Application
    Filed: November 25, 2014
    Publication date: August 24, 2017
    Inventors: Matthew C. L. Keith, Marcin Wysoczynski, Roberto Bolli