Abstract: Compounds for use in treating cancer include inhibitors of KDM5B and/or inducers of HEXIM1 and/or p21 are described herein.

Abstract: Almonds are often harvested off the ground from around trees which have been fertilized with manure. Potentially hazardous microbes are transferred from the husk to the shells during the dehusking process. During deshelling, shell dust with attached microbes escapes into the atmosphere and can permeate an entire packaging facility, contaminating previously uncontaminated packaging and food products. A sterile barrier is provided around the packaging facility. As the almonds in the shell are passed through the barrier, their shells are sanitized. After the nutmeats are removed from the shells, the nutmeats are sanitized again and packaged in packaging which has been sanitized.

Abstract: Almonds, other nuts, grains, dried or dehydrated fruits or vegetables, and other agricultural foodstuffs resting on a mesh conveyor belt (22, 54) pass continuously through a chamber (20, 60) in which they are contacted by a gaseous oxidizing agent at atmospheric pressure as the conveyor belt and food products move continuously through the chamber. In one embodiment, the chamber is disposed through a barrier (56) which isolates a raw product receiving region from downstream processing facilities to prevent cross-contamination downstream. In another embodiment, the chamber (20) is disposed through a barrier (34) which separates a husker (14) from a downstream sheller (40) such that the shells are sanitized prior to releasing the nutmeats from the shells. In the preferred embodiment, the gaseous oxidizing agent is hydrogen peroxide at a 1.