Patents by Inventor Matthew Cadin

Matthew Cadin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for preparing dipeptidyl peptidase IV inhibitors and intermediates therefor
    Publication number: 20050260712
    Abstract: A process for production of cyclopropyl-fused pyrrolidine-based inhibitors of dipeptidyl peptidase IV is provided which employs a BOC-protected amine of the structure prepared by subjecting an acid of the structure to reduce amination by treating the acid with ammonium formate, nicotinamide adenine dinucleotide, dithiothreitol and partially purified phenylalanine dehydrogenase/formate dehydrogenase enzyme concentrate (PDH/FDH) and without isolating treating the resulting amine of the structure 2 with di-tert-butyl dicarbonate to form the BOC-protected amine.
    Type: Application
    Filed: April 12, 2005
    Publication date: November 24, 2005
    Inventors: Michael Politino, Matthew Cadin, Paul Skonezny, Jason Chen