Patents by Inventor Matthew Cooper

Matthew Cooper has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Die Arrangement
    Publication number: 20200232890
    Abstract: A die arrangement for pressing, sintering or stamping comprising: a die body with a cavity extending from an opening at a first end of said die body to an opening at a second end of said die body, and one or more moving parts arranged around the opening at said first end of said die body, wherein each moving part is displaceable between a first position and a second position. The die body may be configurable to receive a die plunger at said second end of said die body, said plunger being displaceable within the cavity.
    Type: Application
    Filed: March 12, 2020
    Publication date: July 23, 2020
    Inventors: Ian Gaskin, Matthew Cooper, Anthony Atkins, Richard Lock
  • Audio Encoding and Decoding Using Presentation Transform Parameters
    Publication number: 20200227052
    Abstract: A method for encoding an input audio stream including the steps of obtaining a first playback stream presentation of the input audio stream intended for reproduction on a first audio reproduction system, obtaining a second playback stream presentation of the input audio stream intended for reproduction on a second audio reproduction system, determining a set of transform parameters suitable for transforming an intermediate playback stream presentation to an approximation of the second playback stream presentation, wherein the transform parameters are determined by minimization of a measure of a difference between the approximation of the second playback stream presentation and the second playback stream presentation, and encoding the first playback stream presentation and the set of transform parameters for transmission to a decoder.
    Type: Application
    Filed: August 24, 2016
    Publication date: July 16, 2020
    Applicants: Dolby Laboratories Licensing Corporation, Dolby International AB
    Inventors: Dirk Jeroen Breebaart, David Matthew Cooper, Leif Jonas Samuelsson, Jeroen Koppens, Rhonda Joy Wilson, Heiko PURNHAGEN, Alexander STAHLMANN
  • NOVEL COMPOUNDS AND USES
    Publication number: 20200207780
    Abstract: The present invention relates to compounds of formula (I): wherein Q is O or S; R1 is a cyclic group substituted with at least one group X, wherein R1 may optionally be further substituted; X is any group comprising a carbonyl group; and R2 is a cyclic group substituted at the ?-position, wherein R2 may optionally be further substituted. The present invention further relates to salts, solvates and prodrugs of such compounds, to pharmaceutical compositions comprising such compounds, and to the use of such compounds in the treatment and prevention of medical disorders and diseases, most especially by the dual action of NLRP3 inhibition and the stimulation of insulin secretion.
    Type: Application
    Filed: May 24, 2017
    Publication date: July 2, 2020
    Inventors: Luke O'Neill, Rebecca Coll, Matthew Cooper, Avril Robertson, Kate Schroder, Angus Murray MacLeod, David John Miller
  • Binaural dialogue enhancement
    Patent number: 10701502
    Abstract: Methods for dialogue enhancing audio content, comprising providing a first audio signal presentation of the audio components, providing a second audio signal presentation, receiving a set of dialogue estimation parameters configured to enable estimation of dialogue components from the first audio signal presentation, applying said set of dialogue estimation parameters to said first audio signal presentation, to form a dialogue presentation of the dialogue components; and combining the dialogue presentation with said second audio signal presentation to form a dialogue enhanced audio signal presentation for reproduction on the second audio reproduction system, wherein at least one of said first and second audio signal presentation is a binaural audio signal presentation.
    Type: Grant
    Filed: August 5, 2019
    Date of Patent: June 30, 2020
    Assignees: Dolby Laboratories Licensing Corporation, Dolby International AB
    Inventors: Leif Jonas Samuelsson, Dirk Jeroen Breebaart, David Matthew Cooper, Jeroen Koppens
  • Audio decoder and decoding method
    Patent number: 10672408
    Abstract: A method for representing a second presentation of audio channels or objects as a data stream, the method comprising the steps of: (a) providing a set of base signals, the base signals representing a first presentation of the audio channels or objects; (b) providing a set of transformation parameters, the transformation parameters intended to transform the first presentation into the second presentation; the transformation parameters further being specified for at least two frequency bands and including a set of multi-tap convolution matrix parameters for at least one of the frequency bands.
    Type: Grant
    Filed: August 23, 2016
    Date of Patent: June 2, 2020
    Assignees: Dolby Laboratories Licensing Corporation, Dolby International AB
    Inventors: Dirk Jeroen Breebaart, David Matthew Cooper, Leif Jonas Samuelsson
  • Methods, apparatus and systems for asymmetric speaker processing
    Patent number: 10659880
    Abstract: A method of processing audio data for replay on a mobile device with a first speaker and a second speaker, wherein the audio data comprises a respective audio signal for each of the first and second speakers, includes: determining a device orientation of the mobile device; if the determined device orientation is vertical orientation, applying a first processing mode to the audio signals for the first and second speakers; and if the determined device orientation is horizontal orientation, applying a second processing mode to the audio signals for the first and second speakers.
    Type: Grant
    Filed: November 14, 2018
    Date of Patent: May 19, 2020
    Assignees: Dolby Laboratories Licensing Corporation, Dolby International AB
    Inventors: Dirk Jeroen Breebaart, Mark David de Burgh, Nicholas Luke Appleton, Heiko Purnhagen, Mark William Gerrard, David Matthew Cooper
  • METHODS FOR GENOME-EDITING AND ACTIVATION OF CELLS
    Publication number: 20200109364
    Abstract: Disclosed herein are methods of genome-editing and transduction of T cells and methods of immunotherapy in using them. In particular, the disclosure relates to engineered chimeric antigen receptor (CAR)-bearing T cells and methods of using the same for the treatment of cancer.
    Type: Application
    Filed: May 31, 2019
    Publication date: April 9, 2020
    Inventors: John DiPersio, Matthew Cooper
  • BUFFER BLOCK APPARATUSES AND SUPPORTING APPARATUSES
    Publication number: 20200070365
    Abstract: A buffer block apparatus for securing a node may be described. The buffer block apparatus may include a first surface having disposed thereon at least one first zero-point feature configured for a first zero-point interface with a robotic assembly apparatus; and a second surface, different from the first surface, configured to connect with a first surface of a node and form a first rigid connection between the buffer block apparatus and the node, wherein the buffer block apparatus provides at least one reference coordinate system with respect to the node.
    Type: Application
    Filed: August 27, 2019
    Publication date: March 5, 2020
    Inventors: Eahab Nagi El Naga, Keith Allen Fleming, Matthew Cooper Keller, Lukas Philip Czinger, Chukwubuikem Marcel Okoli, Michael Thomas Kenworthy, Matthew Coleman Tindall, Justin David Almeleh, Matthew Michael O'Brien, Broc William TenHouten, Oussama Rawas, Juan Cuauhtemoc Munoz, Muhammad Faizan Zafar, Jamison Van Bruch, Thomas Samuel Bowden, JR., Alex James Hamade
  • CHIMERIC ANTIGEN RECEPTOR T CELLS (CAR-T) FOR THE TREATMENT OF CANCER
    Publication number: 20200071397
    Abstract: Disclosed herein are genome-edited chimeric antigen receptor T cells (CAR-T), which can be derived from a cytotoxic T cells, a viral-specific cytotoxic T cell, memory T cells, or gamma delta (??) T cells, and comprise one or more chimeric antigen receptors (CARs) targeting one or more antigens, wherein the CAR-T cell is deficient in one or more antigens to which the one or more CARs specifically binds. In particular, the present disclosure relates to engineered mono, dual, and tandem chimeric antigen receptor (CAR)-bearing T cells (CAR-T) and methods of immunotherapy for the treatment of cancer.
    Type: Application
    Filed: May 31, 2019
    Publication date: March 5, 2020
    Inventors: John DiPersio, Matthew Cooper, Julie O'Neal
  • SUPPRESSION OF CYTOKINE RELEASE SYNDROME IN CHIMERIC ANTIGEN RECEPTOR CELL THERAPY
    Publication number: 20200054675
    Abstract: Disclosed herein are methods of gene editing, or endogenous suppression, of cytokines/chemokines/transcription factors secreted from chimeric antigen receptor (CAR)-bearing immune effector cell such as CAR-T cells for the mitigation of cytokine release syndrome and/or CAR-T associated neuropathy. These methods involve insertion of the CAR into a locus of a cytokine gene, blocking its expression. Also disclosed herein are (CAR)-bearing immune effector cells with CARs inserted into a locus of a cytokine gene, and methods of treatment of diseases with immunotherapy with a reduced incidence of cytokine release syndrome and/or CAR-T associated neuropathy.
    Type: Application
    Filed: May 31, 2019
    Publication date: February 20, 2020
    Inventors: John DiPersio, Matthew Cooper, Alun Carter
  • Diagnostic chip
    Patent number: 10564171
    Abstract: A microfluidic diagnostic chip may comprise a substrate, a plurality of fluidic slots extending through the substrate, a plurality of microfluidic channels each coupled to a respective one of the plurality of fluidic slots to receive a plurality of fluids from the plurality of fluidic slots, and a mixing region in fluid communication with the plurality of fluidic slots to receive the plurality of fluids such that the plurality of fluids are to mix. A diagnostic chip may comprise a number of fluid slots defined through a substrate and a plurality of microfluidic channels coupled to the fluid slots to receive from the fluid slots a plurality of different fluids wherein the microfluidic channels combine and mix the plurality of different fluids.
    Type: Grant
    Filed: January 30, 2015
    Date of Patent: February 18, 2020
    Assignee: Hewlett-Packard Development Company, L.P.
    Inventors: Nicholas Matthew Cooper McGuinness, Chantelle Elizabeth Domingue, Manish Giri, Ed Friesen
  • GENOME-EDITED INVARIANT NATURAL KILLER T (INKT) CELLS FOR THE TREATMENT OF HEMATOLOGIC MALIGNANCIES
    Publication number: 20200040056
    Abstract: Disclosed herein are genome-edited invariant natural killer T (iNKT) cells and methods of immunotherapy using them. In particular, the disclosure relates to engineered chimeric antigen receptor (CAR)-bearing INKT cells (CAR-iNKTs) and methods of using the same for the treatment of cancer.
    Type: Application
    Filed: May 31, 2019
    Publication date: February 6, 2020
    Inventors: John DiPersio, Matthew Cooper, Julie O'Neal
  • Sulfonylureas and related compounds and use of same
    Patent number: 10538487
    Abstract: The present invention provides for certain sulfonyl ureas and related compounds which have advantageous properties and show useful activity in the inhibition of activation of the NLRP3 inflammasome. Such compounds are useful in the treatment of a wide range of disorders in which the inflammation process, or more specifically the NLRP3 inflammasome, have been implicated as being a key factor.
    Type: Grant
    Filed: February 16, 2016
    Date of Patent: January 21, 2020
    Assignees: THE UNIVERSITY OF QUEENSLAND, THE PROVOST, FELLOWS, FOUNDATION SCHOLARS, AND THE OTHER MEMBERS OF BOARD, OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN
    Inventors: Luke O'Neill, Rebecca Coll, Matthew Cooper, Avril Robertson, Kate Schroder
  • GENE EDITING OF CAR-T CELLS FOR THE TREATMENT OF T CELL MALIGNANCIES WITH CHIMERIC ANTIGEN RECEPTORS
    Publication number: 20200000937
    Abstract: The present disclosure provides the use of fratricide-resistant chimeric antigen receptor T (CAR-T) cells targeting antigens expressed by T cell malignancies.
    Type: Application
    Filed: August 3, 2017
    Publication date: January 2, 2020
    Applicant: Washington University
    Inventors: John F. DiPersio, Matthew Cooper
  • Single Speaker Virtualization
    Publication number: 20190387346
    Abstract: Systems, methods, and computer program products of preparing an audio signal for playback on a monaural playback device A system receives an audio signal including one or more components, the one or more components including sound from one or more audio sources. The system processes the audio signal to create a monaural signal. The processing includes introducing one or more monaural cues into at least one component of the one or more components. The monaural signal maintains a presence of the one or more monaural cues. The system then provides the monaural signal to the monaural playback device or to a storage device. The one or more monaural cues are such that, if the monaural signal is played back to a listener using the monaural playback device, the listener experiences a perceived differentiation in direction of the one or more components and/or the one or more audio sources.
    Type: Application
    Filed: June 13, 2019
    Publication date: December 19, 2019
    Applicant: Dolby Laboratories Licensing Corporation
    Inventors: Mark David DE BURGH, Timothy Alan PORT, David Matthew COOPER
  • SULFONYLUREAS AND RELATED COMPOUNDS AND USE OF SAME
    Publication number: 20190359564
    Abstract: The present invention provides for certain sulfonyl ureas and related compounds which have advantageous properties and show useful activity in the inhibition of activation of the NLRP3 inflammasome. Such compounds are useful in the treatment of a wide range of disorders in which the inflammation process, or more specifically the NLRP3 inflammasome, have been implicated as being a key factor.
    Type: Application
    Filed: August 7, 2019
    Publication date: November 28, 2019
    Applicants: THE UNIVERSITY OF QUEENSLAND, THE PROVOST, FELLOWS, FOUNDATION SCHOLARS, AND THE OTHER MEMBERS OF BOARD, OF THE COLLEGE OF THE HOL
    Inventors: Luke O'NEILL, Rebecca COLL, Matthew COOPER, Avril ROBERTSON, Kate SCHRODER
  • Binaural Dialogue Enhancement
    Publication number: 20190356997
    Abstract: Methods for dialogue enhancing audio content, comprising providing a first audio signal presentation of the audio components, providing a second audio signal presentation, receiving a set of dialogue estimation parameters configured to enable estimation of dialogue components from the first audio signal presentation, applying said set of dialogue estimation parameters to said first audio signal presentation, to form a dialogue presentation of the dialogue components; and combining the dialogue presentation with said second audio signal presentation to form a dialogue enhanced audio signal presentation for reproduction on the second audio reproduction system, wherein at least one of said first and second audio signal presentation is a binaural audio signal presentation.
    Type: Application
    Filed: August 5, 2019
    Publication date: November 21, 2019
    Applicants: Dolby Laboratories Licensing Corporation, Dolby International AB
    Inventors: Leif Jonas SAMUELSSON, Dirk Jeroen BREEBAART, David Matthew COOPER, Jeroen KOPPENS
  • HEADTRACKING FOR PARAMETRIC BINAURAL OUTPUT SYSTEM AND METHOD
    Publication number: 20190342694
    Abstract: A method of encoding channel or object based input audio for playback, the method including the steps of: (a) initially rendering the channel or object based input audio into an initial output presentation; (b) determining an estimate of the dominant audio component from the channel or object based input audio and determining a series of dominant audio component weighting factors for mapping the initial output presentation into the dominant audio component; (c) determining an estimate of the dominant audio component direction or position; and (d) encoding the initial output presentation, the dominant audio component weighting factors, the dominant audio component direction or position as the encoded signal for playback.
    Type: Application
    Filed: July 18, 2019
    Publication date: November 7, 2019
    Applicants: DOLBY INTERNATIONAL AB, Dolby Laboratories Licensing Corporation
    Inventors: Dirk Jeroen BREEBAART, David Matthew COOPER, Mark F. DAVIS, David S. McGRATH, Kristofer KJOERLING, Harald MUNDT, Rhonda J. WILSON
  • Headtracking for Pre-Rendered Binaural Audio
    Publication number: 20190327575
    Abstract: A system and method of modifying a binaural signal using headtracking information. The system calculates a delay, a first filter response, and a second filter response, and applies these to the left and right components of the binaural signal according to the headtracking information. The system may also apply headtracking to parametric binaural signals. In this manner, headtracking may be applied to pre-rendered binaural audio.
    Type: Application
    Filed: June 20, 2017
    Publication date: October 24, 2019
    Applicant: DOLBY LABORATORIES LICENSING CORPORATION
    Inventors: C. Phillip Brown, Joshua Brandon Lando, Mark F. Davis, Alan J. Seefeldt, David Matthew Cooper, Dirk Jeroen Breebaart, Rhonda Wilson
  • Binaural dialogue enhancement
    Patent number: 10375496
    Abstract: Methods for dialog enhancing audio content, comprising providing a first audio signal presentation of the audio components, providing a second audio signal presentation, receiving a set of dialog estimation parameters configured to enable estimation of dialog components from the first audio signal presentation, applying said set of dialog estimation parameters to said first audio signal presentation, to form a dialog presentation of the dialog components; and combining the dialog presentation with said second audio signal presentation to form a dialog enhanced audio signal presentation for reproduction on the second audio reproduction system, wherein at least one of said first and second audio signal presentation is a binaural audio signal presentation.
    Type: Grant
    Filed: January 26, 2017
    Date of Patent: August 6, 2019
    Assignees: Dolby Laboratories Licensing Corporation, Dolby International AB
    Inventors: Leif Jonas Samuelsson, Dirk Jeroen Breebaart, David Matthew Cooper, Jeroen Koppens