Abstract: A droplet delivery device includes a housing with a mouthpiece port or outlet from a nasal device for releasing fluid droplets, a fluid reservoir, and an ejector bracket having a membrane positioned between a mesh with a plurality of openings and a vibrating member that is coupled to an electronic transducer, such as an ultrasonic transducer. The transducer vibrates the vibrating member which causes the membrane to push fluid supplied by the reservoir through the mesh to generate droplets in an ejected stream released through the outlet.

Abstract: A droplet delivery device includes an ejector mechanism with an ejector mesh or similar substrate with apertures that is treated by one or more of coatings, roughening, metal layer deposition and laser ablation to provide desirable production and size of droplets, such as in an inhaled aerosol from the device.

Abstract: A droplet delivery device includes a housing with a mouthpiece port or outlet from a nasal device for releasing fluid droplets, a fluid reservoir, and an ejector bracket having a membrane positioned between a mesh with a plurality of openings and a vibrating member that is coupled to an electronic transducer, such as an ultrasonic transducer. The transducer vibrates the vibrating member which causes the membrane to push fluid supplied by the reservoir through the mesh to generate droplets in an ejected stream released through the outlet.

Abstract: An ejector mechanism, droplet delivery device and related methods or delivering small droplets to the respiratory system of a users disclosed. The ejector mechanism comprises a piezoelectric actuator and an aperture plate, the aperture plate having and a plurality of openings formed through its thickness, wherein at least the fluid entrance side of one or more of said openings is configured to provide a surface contact angle of less than 90 degrees and the piezoelectric actuator is operable to oscillate the aperture plate at a frequency to thereby generate an ejected stream of droplets during use. The droplet delivery device is automatically breath actuated by a user when the differential pressure sensor senses a predetermined pressure change. The ejector mechanism is then actuated to generate a plume of droplets having an average ejected particle diameter within the respirable size range having a diameter of less than about 4 um so as to target the respiratory system of the user.