Patents by Inventor Matthew D. Gray

Matthew D. Gray has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of eliciting antibodies that bind to full-length glycosylated HIV-1 Env using multimerized Env cores
    Patent number: 11883485
    Abstract: Sequential immunization strategies to guide the maturation of antibodies against the human immunodeficiency virus (HIV) are described. The sequential immunization strategies utilize an HIV envelope protein (Env) that binds germline (gl) B cells as a first (prime) immunization and an Env with a functional glycosylated N276 as a second (boost) immunization. The sequential immunization strategies successfully elicit neutralizing antibodies against HIV.
    Type: Grant
    Filed: August 29, 2019
    Date of Patent: January 30, 2024
    Assignee: Fred Hutchinson Cancer Center
    Inventors: Leonidas Stamatatos, Andrew McGuire, Katherine Rachael Parks, Matthew D. Gray