Patents by Inventor Matthew David Doroski

Matthew David Doroski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Bifunctional cytotoxic agents
    Patent number: 10391182
    Abstract: Cytotoxic dimers comprising CBI-based and/or CPI-based sub-units, antibody drug conjugates comprising such dimers, and to methods for using the same to treat cancer and other conditions.
    Type: Grant
    Filed: August 2, 2018
    Date of Patent: August 27, 2019
    Assignee: Pfizer Inc.
    Inventors: Andreas Maderna, Matthew David Doroski, Zecheng Chen, Hud Lawrence Risley, Jeffrey Michael Casavant, Christopher John O'Donnell, Alexander M. Porte, Chakrapani Subramanyam
  • BIFUNCTIONAL CYTOTOXIC AGENTS
    Publication number: 20180339060
    Abstract: Cytotoxic dimers comprising CBI-based and/or CPI-based sub-units, antibody drug conjugates comprising such dimers, and to methods for using the same to treat cancer and other conditions.
    Type: Application
    Filed: August 2, 2018
    Publication date: November 29, 2018
    Applicant: PFIZER INC.
    Inventors: Andreas MADERNA, Matthew David DOROSKI, Zecheng CHEN, Hud Lawrence RISLEY, Jeffrey Michael CASAVANT, Christopher John O'DONNELL, Alexander M. PORTE, Chakrapani SUBRAMANYAM
  • Bifunctional cytotoxic agents
    Patent number: 10086085
    Abstract: Cytotoxic dimers comprising CBI-based and/or CPI-based sub-units, antibody drug conjugates comprising such dimers, and to methods for using the same to treat cancer and other conditions.
    Type: Grant
    Filed: January 26, 2015
    Date of Patent: October 2, 2018
    Assignee: Pfizer Inc.
    Inventors: Andreas Maderna, Matthew David Doroski, Zecheng Chen, Hud Lawrence Risley, Jeffrey Michael Casavant, Christopher John O'Donnell, Alexander M. Porte, Chakrapani Subramanyam
  • Cytotoxic peptides and antibody drug conjugates thereof
    Patent number: 9249186
    Abstract: The present invention is directed to cytotoxic pentapeptides, to antibody drug conjugates thereof, and to methods for using the same to treat cancer.
    Type: Grant
    Filed: July 8, 2015
    Date of Patent: February 2, 2016
    Assignee: Pfizer Inc.
    Inventors: Matthew David Doroski, Andreas Maderna, Christopher John O'Donnell, Chakrapani Subramanyam, Beth Vetelino, Russell George Dushin, Pavel Strop, Edmund Idris Graziani
  • CYTOTOXIC PEPTIDES AND ANTIBODY DRUG CONJUGATES THEREOF
    Publication number: 20150307551
    Abstract: The present invention is directed to cytotoxic pentapeptides, to antibody drug conjugates thereof, and to methods for using the same to treat cancer.
    Type: Application
    Filed: July 8, 2015
    Publication date: October 29, 2015
    Inventors: Matthew David DOROSKI, Andreas MADERNA, Christopher John O'DONNELL, Chakrapani SUBRAMANYAM, Beth VETELINO, Russell George DUSHIN, Pavel STROP, Edmund Idris GRAZIANI
  • Cytotoxic peptides and antibody drug conjugates thereof
    Patent number: 9138486
    Abstract: The present invention is directed to cytotoxic pentapeptides, to antibody drug conjugates thereof, and to methods for using the same to treat cancer.
    Type: Grant
    Filed: July 2, 2014
    Date of Patent: September 22, 2015
    Assignee: Pfizer Inc.
    Inventors: Matthew David Doroski, Andreas Maderna, Christopher John O'Donnell, Chakrapani Subramanyam, Beth Vetelino, Russell George Dushin, Pavel Strop, Edmund Idris Graziani
  • BIFUNCTIONAL CYTOTOXIC AGENTS
    Publication number: 20150209445
    Abstract: Cytotoxic dimers comprising CBI-based and/or CPI-based sub-units, antibody drug conjugates comprising such dimers, and to methods for using the same to treat cancer and other conditions.
    Type: Application
    Filed: January 26, 2015
    Publication date: July 30, 2015
    Inventors: Andreas MADERNA, Matthew David DOROSKI, Zecheng CHEN, Hud Lawrence RISLEY, Jeffrey Michael CASAVANT, Christopher John O'DONNELL, Alexander M. PORTE, Chakrapani SUBRAMANYAM
  • CYTOTOXIC PEPTIDES AND ANTIBODY DRUG CONJUGATES THEREOF
    Publication number: 20140363452
    Abstract: The present invention is directed to cytotoxic pentapeptides, to antibody drug conjugates thereof, and to methods for using the same to treat cancer.
    Type: Application
    Filed: July 2, 2014
    Publication date: December 11, 2014
    Inventors: Matthew David DOROSKI, Andreas MADERNA, Christopher John O'DONNELL, Chakrapani SUBRAMANYAM, Beth VETELINO, Russell George DUSHIN, Pavel STROP, Edmund Idris GRAZIANI
  • Cytotoxic peptides and antibody drug conjugates thereof
    Patent number: 8828401
    Abstract: The present invention is directed to cytotoxic pentapeptides, to antibody drug conjugates thereof, and to methods for using the same to treat cancer.
    Type: Grant
    Filed: November 7, 2012
    Date of Patent: September 9, 2014
    Assignee: Pfizer Inc.
    Inventors: Matthew David Doroski, Andreas Maderna, Christopher John O'Donnell, Chakrapani Subramanyam, Beth Vetelino, Russell George Dushin, Pavel Strop, Edmund Idris Graziani