Patents by Inventor Matthew DEFELICE

Matthew DEFELICE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CONTINUOUSLY ADJUSTABLE PILLOW COMPRESSION DEVICE
    Publication number: 20210307544
    Abstract: Disclosed herein are devices and methods to continuously adjust pillow compression and firmness. In some aspects, the devices include at least one cord configured to an adjusting fixture, wherein the at least one cord comprises a plurality of cord segments that extend outward from the adjusting fixture, wherein at least one cord segment of the plurality of cord segments is configured to a pillow. Methods of use and manufacturing also are provided.
    Type: Application
    Filed: April 2, 2021
    Publication date: October 7, 2021
    Inventors: Christopher DeFelice, Matthew DeFelice
  • Methods of diagnosing and treating medullary cystic kidney disease
    Patent number: 10370716
    Abstract: The present invention features a highly sensitive assay for detecting frameshift mutations for high throughput use. Also provided herein are methods for diagnosing or determining a predisposition for developing medullary cystic kidney disease type 1 (MCKD1) in a subject by detecting a frameshift mutation in the GC-rich variable number of tandem repeats (VNTR) sequence of the mucin 1 gene (MUC-1).
    Type: Grant
    Filed: February 10, 2015
    Date of Patent: August 6, 2019
    Assignees: THE BROAD INSTITUTE, INC., THE GENERAL HOSPITAL CORPORATION, INSTITUTO CARLOS SLIM DE LA SALUD, A.C.
    Inventors: Andrew Kirby, Andreas Gnirke, Brendan Blumenstiel, Matthew Defelice, Mark Daly
  • Method for terminating a rope
    Patent number: 9377080
    Abstract: A method for terminating a rope sliding a socket over the rope which includes unlaying the outer strands of the rope, sliding a wedge onto the core such that the outer strands surround the wedge, the wedge includes a central bore axially aligned with the socket, further sliding the wedge such that the core enters the central bore and is terminated by the wedge, pressing the outer strands of the rope against the wedge, sliding the socket over the wedge such that the outer strands are captured between the wedge and the socket, and swaging the socket such that the outer strands are secured.
    Type: Grant
    Filed: October 30, 2014
    Date of Patent: June 28, 2016
    Assignee: The United States of America as represented by the Secretary of the Navy
    Inventor: Matthew DeFelice
  • Method for Terminating a Rope
    Publication number: 20160123429
    Abstract: A method for terminating a rope sliding a socket over the rope which includes unlaying the outer strands of the rope, sliding a wedge onto the core such that the outer strands surround the wedge, the wedge includes a central bore axially aligned with the socket, further sliding the wedge such that the core enters the central bore and is terminated by the wedge, pressing the outer strands of the rope against the wedge, sliding the socket over the wedge such that the outer strands are captured between the wedge and the socket, and swaging the socket such that the outer strands are secured.
    Type: Application
    Filed: October 30, 2014
    Publication date: May 5, 2016
    Applicant: United States of America as represented by the Secretary of the Navy
    Inventor: Matthew DeFelice
  • METHODS OF DIAGNOSING AND TREATING MEDULLARY CYSTIC KIDNEY DISEASE
    Publication number: 20150252423
    Abstract: The present invention features a highly sensitive assay for detecting frameshift mutations for high throughput use. Also provided herein are methods for diagnosing or determining a predisposition for developing medullary cystic kidney disease type 1 (MCKD1) in a subject by detecting a frameshift mutation in the GC-rich variable number of tandem repeats (VNTR) sequence of the mucin 1 gene (MUC-1).
    Type: Application
    Filed: February 10, 2015
    Publication date: September 10, 2015
    Inventors: Andrew KIRBY, Andreas GNIRKE, Brendan Blumenstiel, Matthew DEFELICE, Mark DALY