Patents by Inventor Matthew Douglas Vera

Matthew Douglas Vera has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PRODRUGS OF RILUZOLE AND THEIR METHOD OF USE
    Publication number: 20150045401
    Abstract: Pharmaceutical compositions of the invention include substituted riluzole prodrugs useful for the treatment of cancers including melanoma, breast cancer, brain cancer, and prostate cancer through the release of riluzole. Prodrugs of riluzole have enhanced stability to hepatic metabolism and are delivered into systemic circulation by oral administration, and then cleaved to release riluzole in the plasma via either an enzymatic or general biophysical release process.
    Type: Application
    Filed: March 15, 2013
    Publication date: February 12, 2015
    Inventors: Garry Robert Smith, Allen B. Reitz, Mark McDonnell, Suzie Chen, Matthew Douglas Vera, Benjamin Eric Blass, Jeffrey Claude Pelletier, Venkata Naga Velvadapu, Jay Edward Wrobel
  • 9-aminocarbonylsubstituted derivatives of glycylcyclines
    Patent number: 8101590
    Abstract: This invention provides compounds of Formula I having the structure where R1, R2, R3 and A are defined in the specification or a pharmaceutically acceptable salt thereof useful as antibacterial agents. Compounds according to Formula (II): where Q, R4, R5, R6 and R10 and A are defined in the specification are useful as chemical intermediates.
    Type: Grant
    Filed: August 31, 2006
    Date of Patent: January 24, 2012
    Assignee: Wyeth LLC
    Inventors: Phaik-Eng Sum, Tarek Suhayl Mansour, David Brian How, Darrin William Hopper, Matthew Douglas Vera, Joshua James Sabatini, Jaechul Shim
  • Biaryl sulfonamides and methods for using same
    Patent number: 7923446
    Abstract: The present invention relates to biaryl sulfonamides and their use as, for example, metalloproteinase inhibitors.
    Type: Grant
    Filed: May 31, 2007
    Date of Patent: April 12, 2011
    Assignee: Wyeth LLC
    Inventors: Jason Shaoyun Xiang, Steve Yikkai Tam, Yonghan Hu, Phaik-Eng Sum, David Brian How, Darrin William Hopper, Matthew Douglas Vera, Joshua James Sabatini, Thomas Saltmarsh Rush, III, Elisabeth Ann Morris, Katy Evangelia Georgiadis
  • IMIDAZOPYRIDINE ANALOGS AND THEIR USE AS AGONISTS OF THE WNT-BETA-CATENIN CELLULAR MESSAGING SYSTEM
    Publication number: 20090069319
    Abstract: The present invention relates to imidazopyridine analogs, methods of making imidazopyridine analogs, compositions comprising an imidazopyridine analog, and methods for treating canonical Wnt-?-catenin cellular messaging system-related disorders comprising administering to a subject in need thereof an effective amount of an imidazopyridine analog.
    Type: Application
    Filed: August 26, 2008
    Publication date: March 12, 2009
    Applicant: Wyeth
    Inventors: Joseph Theodore Lundquist, IV, Stephen Marc Bowen, John Francis Mehlmann, Jeffrey Claude Pelletier, Matthew Douglas Vera
  • NAPHTHYLPYRIMIDINE, NAPHTHYLPYRAZINE AND NAPHTHYLPYRIDAZINE ANALOGS AND THEIR USE AS AGONISTS OF THE WNT-BETA-CATENIN CELLULAR MESSAGING SYSTEM
    Publication number: 20090054392
    Abstract: The present invention relates to naphthylpyrimidine analogs, methods of making naphthylpyrimidine analogs, compositions comprising a naphthylpyrimidine analog, and methods for treating canonical Wnt-?-catenin cellular messaging system-related disorders comprising administering to a subject in need thereof an effective amount of a naphthylpyrimidine, naphthylpyrazine and naphthylpyridazine analog.
    Type: Application
    Filed: August 19, 2008
    Publication date: February 26, 2009
    Applicant: Wyeth
    Inventors: Jeffrey Claude Pelletier, Luciana de Araujo Felix, Daniel Michael Green, Diane Barbara Hauze, Joseph Theodore Lundquist, IV, Charles William Mann, John Francis Mehlmann, John Francis Rogers, JR., Matthew Douglas Vera, Albert John Molinari
  • OXAZOLE DERIVATIVES OF TETRACYCLINES
    Publication number: 20080177080
    Abstract: This invention provides compounds of the formula: wherein A?, X and Y are defined in the specification. These compounds are useful as antibacterial agents.
    Type: Application
    Filed: March 24, 2008
    Publication date: July 24, 2008
    Applicant: Wyeth
    Inventors: Phaik-Eng Sum, David Brian How, Darrin William Hopper, Matthew Douglas Vera, Joshua James Sabatini
  • Oxazole derivatives of tetracyclines
    Patent number: 7365087
    Abstract: This invention provides compounds of the formula: wherein A?, X and Y are defined in the specification. These compounds are useful as antibacterial agents.
    Type: Grant
    Filed: December 13, 2006
    Date of Patent: April 29, 2008
    Assignee: Wyeth
    Inventors: Phaik-Eng Sum, David Brian How, Darrin William Hopper, Matthew Douglas Vera, Joshua James Sabatini
  • Biaryl sulfonamides and methods for using same
    Patent number: 7268135
    Abstract: The present invention relates to biaryl sulfonamides and their use as, for example, metalloproteinase inhibitors.
    Type: Grant
    Filed: December 1, 2004
    Date of Patent: September 11, 2007
    Assignee: Wyeth
    Inventors: Jason Shaoyun Xiang, Steve Yikkai Tam, Yonghan Hu, Phaik-Eng Sum, David Brian How, Darrin William Hopper, Matthew Douglas Vera, Joshua James Sabatini, Thomas Saltmarsh Rush, III
  • Oxazole derivatives of tetracyclines
    Patent number: 7176225
    Abstract: This invention provides compounds of the formula: wherein A?, X and Y are defined in the specification. These compounds are useful as antibacterial agents.
    Type: Grant
    Filed: December 8, 2004
    Date of Patent: February 13, 2007
    Assignee: Wyeth
    Inventors: Phaik-Eng Sum, David Brian How, Darrin William Hopper, Matthew Douglas Vera, Joshua James Sabatini