Patents by Inventor Matthew E. DOWNS

Matthew E. DOWNS has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11416653
    Abstract: Systems and methods for generating a numerical model of the human head are provided. A numerical model may be created by generating a data array in a magnetic resonance modeling system, each cell of the array corresponding to a location in the head. The cells may be grouped into one or more regions, each group corresponding to a segment of the head. The cells of the array may be populated with values corresponding to tissue properties relevant to MR imaging. Tissue property values may be selected for each region based on one or more probability distributions. For each region and each tissue property, a value may be selected based on a corresponding probability distribution. Selected tissue property values may be input into cells in the array corresponding to the region with which the probability distribution is associated. The numerical model may be used as an input to an MRI simulator.
    Type: Grant
    Filed: May 15, 2019
    Date of Patent: August 16, 2022
    Assignee: The MITRE Corporation
    Inventors: Matthew E. Downs, Joseph Dagher
  • Publication number: 20200364312
    Abstract: Systems and methods for generating a numerical model of the human head are provided. A numerical model may be created by generating a data array in a magnetic resonance modeling system, each cell of the array corresponding to a location in the head. The cells may be grouped into one or more regions, each group corresponding to a segment of the head. The cells of the array may be populated with values corresponding to tissue properties relevant to MR imaging. Tissue property values may be selected for each region based on one or more probability distributions. For each region and each tissue property, a value may be selected based on a corresponding probability distribution. Selected tissue property values may be input into cells in the array corresponding to the region with which the probability distribution is associated. The numerical model may be used as an input to an MRI simulator.
    Type: Application
    Filed: May 15, 2019
    Publication date: November 19, 2020
    Applicant: The MITRE Corporation
    Inventors: Matthew E. DOWNS, Joseph DAGHER
  • Publication number: 20200023206
    Abstract: Systems for modulating one or more neurons using focused ultrasound (FUS) include a transducer mount, a recording chamber disposed at an angle relative the transducer mount and configured to contain the one or more neurons within the recording chamber, an ultrasound transducer disposed on the transducer mount to provide an ultrasound stimulus having one or more ultrasound parameters to the one or more neurons, and a processor configured to adjust the one or more ultrasound parameters to produce one or more action potentials from the one or more neurons in response to the ultrasound stimulus, the one or more action potentials corresponding to one or more of a pain or sensation response, a pain or sensation suppression, or neural control of organ function induced by the one or more neurons.
    Type: Application
    Filed: March 18, 2019
    Publication date: January 23, 2020
    Applicant: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
    Inventors: Elisa E. KONOFAGOU, Ellen A. LUMPKIN, Yoshichika BABA, Chi-Kun TONG, Benjamin HOFFMAN, Matthew E. DOWNS, Danny M. FLOREZ PAZ