Abstract: Nanoscale multiple emulsions, nanoparticles resulting therefrom and methods of making and using thereof are described. The nanoscale multiple emulsions are typically double nanoemulsions, such as oil-in-water-in-oil (O1/W/O2) nanoemulsions, in which nanodroplets of the first oil (O1) phase are suspended in the aqueous (W) phase and together are dispersed in the second oil (O2) phase. The double nanoemulsions are stable with high encapsulation efficiency allowing templating to form multiphase nanoparticles. The multiphase nanoparticles include nanodroplets of O1 phase dispersed in a continuous matrix that can be a liquid, a gel, or a solid at room temperature and pressure. Methods of making the double nanoemulsions include high-energy forces and serial nanoemulsifications.

Abstract: Nanoscale multiple emulsions, nanoparticles resulting therefrom and methods of making and using thereof are described. The nanoscale multiple emulsions are typically double nanoemulsions, such as oil-in-water-in-oil (O1/W/O2) nanoemulsions, in which nanodroplets of the first oil (O1) phase are suspended in the aqueous (W) phase and together are dispersed in the second oil (O2) phase. The double nanoemulsions are stable with high encapsulation efficiency allowing templating to form multiphase nanoparticles. The multiphase nanoparticles include nanodroplets of O1 phase dispersed in a continuous matrix that can be a liquid, a gel, or a solid at room temperature and pressure. Methods of making the double nanoemulsions include high-energy forces and serial nanoemulsifications.

Abstract: Disclosed herein are star-shaped macromolecular structures comprising a hyper-branched silicon containing core grafted with a well-defined and controllable number of alkyl (methyl)acrylate (co)polymer arms. The presence of the robust inorganic core provides additional resilience against mechanical degradation and therefore enhanced additive life time. Control over the additive architecture was complemented by tunability of the length of the grafted polymers by making use of controlled radical based polymerization techniques. The performance of these novel inorganic-organic star-shaped hybrids were compared to traditional fully organic lubricant additives. Detailed analysis revealed the multi-functional character of the hybrids by simultaneously performing as bulk viscosity modifiers, boundary lubricant, and wear protectants while being dispersed in a commercially available base oil for automotive lubrication purposes.

Abstract: The present invention generally relates to compositions, methods, and systems relating to controlled crystallization and/or nucleation of a molecular species. In some embodiments, the crystallization and/or nucleation of the molecular species may be controlled by tuning the surface chemistry and/or the morphology of a crystallization substrate. In some embodiments, the molecular species is a small organic molecule (e.g., pharmaceutically active agent).

Abstract: The present invention generally relates to compositions, methods, and systems relating to controlled crystallization and/or nucleation of a molecular species. In some embodiments, the crystallization and/or nucleation of the molecular species may be controlled by tuning the surface chemistry and/or the morphology of a crystallization substrate. In some embodiments, the molecular species is a small organic molecule (e.g., pharmaceutically active agent).

Abstract: The present invention generally relates to compositions, methods, and systems relating to controlled crystallization and/or nucleation of a molecular species. In some embodiments, the crystallization and/or nucleation of the molecular species may be controlled by tuning the surface chemistry and/or the morphology of a crystallization substrate. In some embodiments, the molecular species is a small organic molecule (e.g., pharmaceutically active agent).

Abstract: The invention comprises a method of enhancing viscosity and/or viscoelasticity of surfactant solution using nanoparticles. The particle allow a formulator to tailor-make a solution of defined rheology (viscosity and/or viscoelasticity) using nanoparticles to control these properties. Further, the particles allow independent control of each of the variable and further allow the variable to be controlled without use of additional surfactants, polymer and other components traditionally used for this end. The invention also comprises compositions thereof.