Patents by Inventor Matthew F. Smith
Matthew F. Smith has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240158213Abstract: Automated jackstand systems and methods deploy a jackstand to support a front end of a trailer parked at an automated loading dock. The jackstand prevents collapse of the trailer's landing gear and prevents upending of the trailer during loading and unloading. Advantageously, by deploying the jackstand automatically, presence of personnel in the yard where tractors and trailers are moving is not required.Type: ApplicationFiled: January 22, 2024Publication date: May 16, 2024Inventors: Andrew F. Smith, Martin Edward Sotola, Peter James, Lawrence S. Klein, Matthew Steven Johannes, Jonathan Record, Garold McKinney
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Publication number: 20240152139Abstract: A system and method for operation of an autonomous vehicle (AV) yard truck is provided. A processor facilitates autonomous movement of the AV yard truck, and connection to and disconnection from trailers. A plurality of sensors are interconnected with the processor that sense terrain/objects and assist in automatically connecting/disconnecting trailers. A server, interconnected, wirelessly with the processor, that tracks movement of the truck around and determines locations for trailer connection and disconnection. A door station unlatches/opens rear doors of the trailer when adjacent thereto, securing them in an opened position via clamps, etc. The system computes a height of the trailer, and/or if landing gear of the trailer is on the ground and interoperates with the fifth wheel to change height, and whether docking is safe, allowing a user to take manual control, and optimum charge time(s). Reversing sensors/safety, automated chocking, and intermodal container organization are also provided.Type: ApplicationFiled: October 9, 2023Publication date: May 9, 2024Inventors: Andrew F. Smith, Lawrence S. Klein, Stephen A. Langenderfer, Martin E. Sotola, Vikas Bahl, Mark H. Rosenblum, Peter James, Dale Dee Rowley, Matthew S. Johannes, Gary Michael Seminara, Jeremy M. Nett
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Publication number: 20240131886Abstract: A system and method for operation of an autonomous vehicle (AV) yard truck is provided. A processor facilitates autonomous movement of the AV yard truck, and connection to and disconnection from trailers. A plurality of sensors are interconnected with the processor that sense terrain/objects and assist in automatically connecting/disconnecting trailers. A server, interconnected, wirelessly with the processor, that tracks movement of the truck around and determines locations for trailer connection and disconnection. A door station unlatches/opens rear doors of the trailer when adjacent thereto, securing them in an opened position via clamps, etc. The system computes a height of the trailer, and/or if landing gear of the trailer is on the ground and interoperates with the fifth wheel to change height, and whether docking is safe, allowing a user to take manual control, and optimum charge time(s). Reversing sensors/safety, automated chocking, and intermodal container organization are also provided.Type: ApplicationFiled: July 23, 2023Publication date: April 25, 2024Inventors: Andrew F. Smith, Lawrence S. Klein, Stephen A. Langenderfer, Martin E. Sotola, Vikas Bahl, Mark H. Rosenblum, Peter James, Dale Dee Rowley, Matthew S. Johannes, Gary Michael Seminara, Jeremy M. Nett, Christopher T. Bate, Michael Patrick Cutter
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Patent number: 11964989Abstract: Compounds that inhibit KRas G12D. In particular, compounds that inhibit the activity of KRas G12D, pharmaceutical compositions comprising the compounds and methods of use therefor, and in particular, methods of treating cancer. The compounds have a general structure represented by Formula (I): or a pharmaceutically acceptable salt thereof.Type: GrantFiled: July 20, 2022Date of Patent: April 23, 2024Assignees: Mirati Therapeutics, Inc., Array BioPharma Inc.Inventors: Xiaolun Wang, Aaron Craig Burns, James Gail Christensen, John Michael Ketcham, John David Lawson, Matthew Arnold Marx, Christopher Ronald Smith, Shelley Allen, James F. Blake, Mark Joseph Chicarelli, Joshua Ryan Dahlke, Donghua Dai, Jay Bradford Fell, John Peter Fischer, Macedonio J. Mejia, Brad Newhouse, Phong Nguyen, Jacob Matthew O'Leary, Spencer Pajk, Martha E. Rodriguez, Pavel Savechenkov, Tony P. Tang, Guy P.A. Vigers, Qian Zhao, Dean Russell Kahn, John Gaudino, Michael Christopher Hilton
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Publication number: 20240101553Abstract: The present invention relates to compounds that inhibit KRas G12C. In particular, the present invention relates to compounds that irreversibly inhibit the activity of KRas G12C, pharmaceutical compositions comprising the compounds and methods of use therefor.Type: ApplicationFiled: August 4, 2023Publication date: March 28, 2024Inventors: Matthew Arnold MARX, James Gail CHRISTENSEN, Christopher Ronald SMITH, James F. BLAKE, Laurence E. BURGESS, Mark Joseph CHICARELLI, Adam COOK, Jay Bradford FELL, John P. FISCHER, Macedonio J. MEJIA, Martha E. RODRIGUEZ, Pavel SAVECHENKOV, Tony P. TANG, Guy P.A. VIGERS
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Publication number: 20160018347Abstract: Described herein are devices, systems, and methods for determining the composition of liquids, including the identity of one or more drugs in the liquid, the concentration of the drug, and the type of diluent using immittance spectroscopy. These devices, systems and methods are particularly useful for describing the identity and, in some variations, concentration of one or more components of a medical liquid such as intravenous fluid.Type: ApplicationFiled: March 11, 2014Publication date: January 21, 2016Inventors: Vladimir J. DRBAL, Matthew F. SMITH, William W. ALSTON, Michael J. WEICKERT, Leonid F. MATSIEV, Kit BLANKE
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Publication number: 20140375324Abstract: Described herein are devices, systems, and methods for determining the composition of liquids, including the identity of one or more drugs in the liquid, the concentration of the drug, and the type of diluent using immittance spectroscopy. These devices, systems and methods are particularly useful for describing the identity and, in some variations, concentration of one or more components of a medical liquid such as intravenous fluid. In particular, described herein are devices, systems and methods that may operate in low ionic strength diluents. Also described are methods of recognizing complex immittance spectrograph patterns to determine the composition of a liquid by pattern recognition.Type: ApplicationFiled: August 12, 2014Publication date: December 25, 2014Inventors: Leonid F. MATSIEV, Michael J. WEICKERT, James W. BENNETT, Matthew F. SMITH, Svetlana LITVINTSEVA, Kit BLANKE
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Patent number: 8838395Abstract: Described herein are devices, systems, and methods for determining the composition of liquids, including the identity of one or more drugs in the liquid, the concentration of the drug, and the type of diluent using immittance spectroscopy. These devices, systems and methods are particularly useful for describing the identity and, in some variations, concentration of one or more components of a medical liquid such as intravenous fluid. In particular, described herein are devices, systems and methods that may operate in low ionic strength diluents. Also described are methods of recognizing complex immittance spectrograph patterns to determine the composition of a liquid by pattern recognition.Type: GrantFiled: September 9, 2011Date of Patent: September 16, 2014Assignee: S.E.A. Medical Systems, Inc.Inventors: Leonid F. Matsiev, Michael J. Weickert, James W. Bennett, Matthew F. Smith, Svetlana Litvintseva, Kit Blanke
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Publication number: 20120065617Abstract: Described herein are devices, systems, and methods for determining the composition of liquids, including the identity of one or more drugs in the liquid, the concentration of the drug, and the type of diluent using immittance spectroscopy. These devices, systems and methods are particularly useful for describing the identity and, in some variations, concentration of one or more components of a medical liquid such as intravenous fluid. In particular, described herein are devices, systems and methods that may operate in low ionic strength diluents. Also described are methods of recognizing complex immittance spectrograph patterns to determine the composition of a liquid by pattern recognition.Type: ApplicationFiled: September 9, 2011Publication date: March 15, 2012Inventors: Leonid F. Matsiev, Michael J. Weickert, James W. Bennett, Matthew F. Smith, Svetlana Litvintseva, Kit Blanke
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Patent number: 7858049Abstract: A parallel reactor system including a reactor and vessels in the reactor for holding reaction mixtures, and a cannula for introducing fluid reaction material into the vessels. A robot system is operable to insert the cannula into cannula passages in the reactor for delivery of reaction materials, including condensed gases, to respective vessels, and to withdraw the cannula from the cannula passages after delivery. Related methods are also disclosed.Type: GrantFiled: December 20, 2007Date of Patent: December 28, 2010Assignee: Freeslate, Inc.Inventors: Matthew F. Smith, John F. Varni, G. Cameron Dales, Trevor G. Frank, Rakesh Jain, Lynn Van Erden
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Patent number: 7597852Abstract: Apparatus and methods for screening a library of materials. Materials are provided in a plurality of locations on a substrate. The locations include first regions that are sufficiently transparent to a first form of radiation to permit analysis of the portion of the sample material supported in the first region using a first analytical technique, and second regions that are sufficiently transparent to a second form of radiation to permit analysis of a portion of the sample supported in the second region using a second analytical technique, but are insufficiently transparent to the first form of radiation to permit analysis of the portion of the sample material supported in the second region using the first analytical technique. Sample materials are screened at one or more sample locations of the substrate using the first analytical technique in the first region and the second analytical technique in the second region.Type: GrantFiled: September 2, 2005Date of Patent: October 6, 2009Assignee: Symyx Solutions, Inc.Inventors: Peter J. Desrosiers, Matthew F. Smith
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Publication number: 20080138260Abstract: A parallel reactor system including a reactor and vessels in the reactor for holding reaction mixtures, and a cannula for introducing fluid reaction material into the vessels. A robot system is operable to insert the cannula into cannula passages in the reactor for delivery of reaction materials, including condensed gases, to respective vessels, and to withdraw the cannula from the cannula passages after delivery. Related methods are also disclosed.Type: ApplicationFiled: December 20, 2007Publication date: June 12, 2008Applicant: SYMYX TECHNOLOGIES, INCInventors: Matthew F. Smith, John F. Varni, G. Cameron Dales, Trevor G. Frank, Rakesh Jain, Lynn Van Erden
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Patent number: 7335513Abstract: A parallel reactor system including a reactor and vessels in the reactor for holding reaction mixtures, and a cannula for introducing fluid reaction material into the vessels. A robot system is operable to insert the cannula into cannula passages in the reactor for delivery of reaction materials, including condensed gases, to respective vessels, and to withdraw the cannula from the cannula passages after delivery. Related methods are also disclosed.Type: GrantFiled: January 28, 2002Date of Patent: February 26, 2008Assignee: Symyx Technologies, Inc.Inventors: Matthew F. Smith, John F. Varni, G. Cameron Dales, Trevor G. Frank, Rakesh Jain, Lynn Van Erden
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Publication number: 20020106813Abstract: A parallel reactor system including a reactor and vessels in the reactor for holding reaction mixtures, and a cannula for introducing fluid reaction material into the vessels. A robot system is operable to insert the cannula into cannula passages in the reactor for delivery of reaction materials, including condensed gases, to respective vessels, and to withdraw the cannula from the cannula passages after delivery. Related methods are also disclosed.Type: ApplicationFiled: January 28, 2002Publication date: August 8, 2002Applicant: Symyx Technologies, Inc.Inventors: Matthew F. Smith, John F. Varni, G. Cameron Dales, Trevor G. Frank, Rakesh Jain, Lynn Van Erden