Abstract: Canisters are provided that include a cylindrical body and a cap welded to the body to define a cavity filled with carbon dioxide or other fluid. The canisters may be loaded into a medical device, e.g., to provide an energy source for operating the device. Methods for making such canisters are also provided.

Abstract: Gas-powered fluid injection systems and methods are disclosed, e.g., for delivering fluids into a patient's body. An injection device comprises a driver housing which forms and/or encloses a gas pressure source, an actuation piston driven by the gas pressure source and a hydraulic fluid pressurized by movement of the actuation piston. The hydraulic fluid flows through an adjustable valve into a plunger lumen which pushes a plunger of a fluid dispensing device, such as a syringe, to dispense an injection fluid, such as a medicament. The injection device has a movable plunger sleeve which receives the plunger of the fluid dispensing device. The plunger sleeve is moved during the activation and de-activation of the injection device such that it relieves residual pressure in the fluid dispensing device thereby preventing the fluid dispensing device from continuing to dispense injection fluid after the injection device has been de-actuated.

Abstract: Devices and methods are provided for delivering an agent into a patient's body using an injection device that includes a drive module and an injector module coupled to the drive module. The drive module includes a canister and puncture mechanism in a first chamber, a plunger in a second chamber communicating with the first chamber, and an actuator that moves the puncture mechanism to cause a puncture pin thereon to penetrate a septum of the canister and cause the gas within the canister to flow through the first chamber around the canister, and into the second chamber. The injector module includes a piston slidably disposed within an agent chamber and coupled to the distal end of the plunger such that, when the plunger moves from a retracted position to an extended position, the piston is advanced within the agent chamber to deliver an agent therein into a patient's body.

Abstract: An intraocular lens inserter can include an energy storage portion, an actuator portion that provides temperature compensation, and a lens support portion. The energy storage portion can include a compressible energy storage device, such as a compressible fluid, springs, and other devices. The inserter can include an actuator portion operating with a substantially incompressible fluid. The actuator can be configured to provide an operator with control over the release of pressurized fluid so as to move a plunger for the discharge of a lens from an intraocular lens cartridge, discharge of the lens being limited based at least in part on pressure feedback from the pressurized fluid due temperature increases.

Abstract: Devices and methods are provided for delivering fluid into a patient's body. In an exemplary embodiment, the device may include a syringe cartridge and a syringe driver that may be coupled to the cartridge. The cartridge may include a housing including a proximal end, a distal end, and defining an interior, the cartridge further including a piston slidably disposed within the interior for delivering fluid within the interior through a port in the distal end. The driver may include a plunger for advancing the piston within the interior of the housing, a source of pressurized fluid, a valve, and an actuator member coupled to the valve for selectively opening a flow path from the source to the plunger to control flow of the pressurized fluid to advance the plunger to deliver fluid from the interior of the housing at a desired rate.

Abstract: Canisters are provided that include a cylindrical body and a cap welded to the body to define a cavity filled with carbon dioxide or other fluid. The canisters may be loaded into a medical device, e.g., to provide an energy source for operating the device. Methods for making such canisters are also provided.

Abstract: An intraocular lens inserter can include an energy storage portion, an actuator portion that provides temperature compensation, and a lens support portion. The energy storage portion can include a compressible energy storage device, such as a compressible fluid, springs, and other devices. The inserter can include an actuator portion operating with a substantially incompressible fluid. The actuator can be configured to provide an operator with control over the release of pressurized fluid so as to move a plunger for the discharge of a lens from an intraocular lens cartridge, discharge of the lens being limited based at least in part on pressure feedback from the pressurized fluid due temperature increases.

Abstract: The burr hole plug comprises a plug base configured for being mounted around a burr hole, and having an aperture through which an elongated medical device exiting the burr hole may pass. The burr hole plug further comprises a retainer configured for being mounted within the plug base aperture. The retainer includes a retainer support, a slot formed in the retainer support for receiving the medical device, and a clamping mechanism having a clamping bar and a flange slidably engaged with the retainer support to laterally slide the clamping bar to secure the medical device. A method comprises introducing the medical device through the burr hole, mounting the plug base around the burr hole, mounting the retainer within the plug base aperture, receiving the medical device into the slot, and sliding the slidable flange relative to the retainer support to laterally slide to secure the medical device.

Abstract: The burr hole plug comprises a plug base configured for being mounted around a burr hole, and having an aperture through which an elongated medical device exiting the burr hole may pass. The burr hole plug further comprises a retainer configured for being mounted within the plug base aperture. The retainer includes a retainer support, a slot formed in the retainer support for receiving the medical device, and a clamping mechanism having a clamping bar and a flange slidably engaged with the retainer support to laterally slide the clamping bar to secure the medical device. A method comprises introducing the medical device through the burr hole, mounting the plug base around the burr hole, mounting the retainer within the plug base aperture, receiving the medical device into the slot, and sliding the slidable flange relative to the retainer support to laterally slide to secure the medical device.

Abstract: A burr hole plug comprises a plug base configured for being mounted around a burr hole. The plug base includes an aperture through which an elongated medical device exiting the burr hole may pass. The burr hole plug further comprises a retainer configured for being mounted within the aperture of the plug base. The retainer further includes first and second slidable clamping mechanisms configured for securing the medical devices therebetween within the aperture of the plug base. A method comprises introducing the medical device through the burr hole, mounting a plug base around the burr hole, such that the medical device extends through the plug base aperture, mounting the retainer within the aperture of the plug base, and sliding the first and second clamping mechanisms secure the medical device therebetween.

Abstract: A lead has a paddle body with a non-conductive material and multiple electrodes disposed within the non-conductive material. At least one of the electrodes includes one or more anchoring arrangement, such as opening(s) through the electrode through which the non-conductive material can pass; anchors that extend away from the electrode and into the non-conductive material of the paddle body; or flow-through anchors attached to the electrode with an opening through which the non-conductive material may pass.

Abstract: A linkage arrangement is disclosed to provide an articulated machine with an arrangement that allows two frame structures to both articulate and oscillate relative to one another. The linkage arrangement includes a three point pivot arrangement with an angled link. Two of the pivots provide for articulation while two of the pivots provide for oscillation. The two pivots involved for oscillation are of lower overall height than the overall height for the two pivots providing the articulation, thereby reducing overall machine height while maintaining structural integrity.

Abstract: A lead has a paddle body with a non-conductive material and multiple electrodes disposed within the nonconductive material. At least one of the electrodes includes one or more anchoring arrangement, such as opening(s) through the electrode through which the non-conductive material can pass; anchors that extend away from the electrode and into the non-conductive material of the paddle body; or flow-through anchors attached to the electrode with an opening through which the non-conductive material may pass.

Abstract: A lead has a paddle body with a non-conductive material and multiple electrodes disposed within the non-conductive material. At least one of the electrodes includes one or more anchoring arrangement, such as opening(s) through the electrode through which the non-conductive material can pass; anchors that extend away from the electrode and into the non-conductive material of the paddle body; or flow-through anchors attached to the electrode with an opening through which the non-conductive material may pass.

Abstract: A burr hole plug comprises a plug base configured for being mounted around a burr hole. The plug base includes an aperture through which an elongated medical device exiting the burr hole may pass. The burr hole plug further comprises a retainer configured for being mounted within the aperture of the plug base. The retainer further includes first and second slidable clamping mechanisms configured for securing the medical devices therebetween within the aperture of the plug base. A method comprises introducing the medical device through the burr hole, mounting a plug base around the burr hole, such that the medical device extends through the plug base aperture, mounting the retainer within the aperture of the plug base, and sliding the first and second clamping mechanisms secure the medical device therebetween.

Abstract: A linkage arrangement is disclosed to provide an articulated machine with an arrangement that allows two frame structures to both articulate and oscillate relative to one another. The linkage arrangement includes a three point pivot arrangement with an angled link. Two of the pivots provide for articulation while two of the pivots provide for oscillation. The two pivots involved for oscillation are of lower overall height than the overall height for the two pivots providing the articulation, thereby reducing overall machine height while maintaining structural integrity.

Abstract: A burr hole plug comprises a plug base including a flange configured for being mounted around a burr hole, an aperture through which an elongated medical device may pass, and tabs configured for extending within the cranial burr hole to center the plug base relative to the cranial burr hole. The burr hole plug further comprises a retainer configured for being mounted within the aperture of the plug base to secure the medical device. A method may comprise locating the plug base within a burr hole, such that the tabs are disposed within the burr hole to center the plug base relative to the cranial burr hole, introducing the elongated medical device through the cranial burr hole and into the brain tissue of the patient, mounting the retainer within the aperture of the plug base, and actuating the retainer to secure the medical device.

Abstract: A lead has a paddle body with a non-conductive material and multiple electrodes disposed within the non-conductive material. At least one of the electrodes includes one or more anchoring arrangement, such as opening(s) through the electrode through which the non-conductive material can pass; anchors that extend away from the electrode and into the non-conductive material of the paddle body; or flow-through anchors attached to the electrode with an opening through which the non-conductive material may pass.