Abstract: The present disclosure generally relates to, inter alia, methods, kits, and systems for the diagnosis and/or treating various health conditions, such as proliferative disorders (e.g., cancers), associated with a decreased level or a loss of CD58 expression or molecular alterations in CD58 activity.

Abstract: Systems and methods are provided to re-authenticating an electronic device. The systems and methods (1) receive from an electronic device, a request to access a local access network on-board a vehicle, the request including a device identifier of the electronic device; (2) query, using the device identifier, an access profile assigned to the electronic device to determine that the electronic device has previously been authenticated during a first communication session, wherein the access profile is assigned to the electronic device based upon an indication of a user selection received from the electronic device; (3) monitor network usage associated with the electronic device during a second communication session; and (4) automatically re-authenticate the electronic device based on the monitoring.

Abstract: Systems and methods are provided to re-authenticating an electronic device. The systems and methods (1) receive from an electronic device, a request to access a local access network on-board a vehicle, the request including a device identifier of the electronic device; (2) query, using the device identifier, an access profile assigned to the electronic device to determine that the electronic device has previously been authenticated during a first communication session, wherein the access profile is assigned to the electronic device based upon an indication of a user selection received from the electronic device; (3) monitor network usage associated with the electronic device during a second communication session; and (4) automatically re-authenticate the electronic device based on the monitoring.

Abstract: There are provided herein, inter alia, complexes, compositions and methods for the delivery of nucleic acid into a cell in vivo. The complexes, compositions and methods may facilitate complexation, protection, delivery and release of oligonucleotides and polyanionic cargos into target cells, tissues, and organs both in vitro and in vivo.

Abstract: A fuel cell air management system includes a compressor receiving ambient air at a compressor inlet and supplying compressed air at a compressor outlet. A mechanical power transmission is connected to an electric machine. The mechanical power transmission is operatively connected to the compressor. An expander is operatively connected to the mechanical power transmission. A recuperator is connected to the compressor outlet. The recuperator includes a recuperator inlet and a recuperator outlet. An intercooler is coupled to the recuperator outlet. A fuel cell stack is connected to an intercooler outlet. The fuel cell stack includes a fuel cell outlet connected to the recuperator and the recuperator includes an exhaust connected to the expander. A water separator is connected to an outlet of the expander. The water separator is coupled to a pump metering a specified dose of water to a specified location selected from the compressor inlet, the compressor outlet, the recuperator outlet or combinations thereof.

Abstract: An attachable adherence monitor that may be attached to different types of medicant dispensers is disclosed. The adherence monitor has a sensor body including sensing electronics that are triggered to indicate the activation of a medicant dispenser and assign a timestamp to the activation. The sensor body includes a storage device storing data indicating the activation of the medicant dispenser. The sensor body includes a connector conduit. A number of attachment modules are provided. Each of the attachment modules includes a connector that allows attachment to the sensor body via the connector conduit. A first attachment module includes a first attachment mechanism for attaching the sensor body to a first medicant dispenser. A second attachment module includes a different second attachment mechanism for attaching the sensor body to a second different medicant dispenser.

Abstract: The present disclosure generally relates to methods that utilize cell-free DNA from a liquid biopsy of an individual to track DNA from both the tumor and the chimeric antigen receptor (CAR) T-cells. The present disclosure further relates to methods of predicting individuals' response to therapy, e.g., CAR T-cell therapies. Additionally, the present disclosure relates to methods of treating individuals with cancer, such as lymphoma.

Abstract: A manufacturing method uses layered slabs to create a final pattern for a mold or for creating the mold itself. The method includes: preparing a desired number of slabs including a first slab and a second slab; machining the first slab; machining the second slab; and after the second slab is coupled to the first slab, repeating the machining step for each additional slab included in the desired number of slabs to form the final pattern or mold.

Abstract: Systems and methods are provided to re-authenticating an electronic device. The systems and methods (1) receive from an electronic device, a request to access a local access network on-board a vehicle, the request including a device identifier of the electronic device; (2) query, using the device identifier, an access profile assigned to the electronic device to determine that the electronic device has previously been authenticated during a first communication session, wherein the access profile is assigned to the electronic device based upon an indication of a user selection received from the electronic device; (3) monitor network usage associated with the electronic device during a second communication session; and (4) automatically re-authenticate the electronic device based on the monitoring.

Abstract: There are provided herein, inter alia, complexes, compositions and methods for the delivery of nucleic acid into a cell in vivo. The complexes, compositions and methods may facilitate complexation, protection, delivery and release of oligonucleotides and polyanionic cargos into target cells, tissues, and organs both in vitro and in vivo.