Patents by Inventor Matthew Frieman

Matthew Frieman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BROAD SPECTRUM ANTIVIRAL COMPOUNDS TARGETING THE SKI COMPLEX
    Publication number: 20240132484
    Abstract: Compounds and methods of using the same for treating conditions alleviated by SKI complex inhibition, viral replication inhibition, or interferon signaling inducement are provided.
    Type: Application
    Filed: December 3, 2021
    Publication date: April 25, 2024
    Inventors: Matthew Frieman, Alexander D. Mackerell, JR., Stuart WESTON
  • BROAD SPECTRUM ANTIVIRAL COMPOUNDS TARGETING THE SKI COMPLEX
    Publication number: 20220259180
    Abstract: Compounds and methods of using the same for treating conditions alleviated by SKI complex inhibition, viral replication inhibition, or interferon signaling inducement are provided.
    Type: Application
    Filed: June 5, 2020
    Publication date: August 18, 2022
    Inventors: Matthew FRIEMAN, Stuart WESTON, Alexander D. MACKERELL
  • ADJUVANTS FOR IMMUNOGENIC COMPOSITIONS AND METHODS OF USE THEREOF
    Publication number: 20220233688
    Abstract: The present invention provides pharmaceutical compositions capable of inducing an immune response in a subject, comprising an effective amount of a viral immunogen and an adjuvant, wherein the adjuvant comprises a lipid A mimetic. Methods for inducing an immune response are also provided.
    Type: Application
    Filed: June 8, 2020
    Publication date: July 28, 2022
    Inventors: Matthew Frieman, Robert Haupt, Robert K. Ernst
  • Methods of treating coronavirus infection
    Patent number: 10434116
    Abstract: The present invention provides methods for treating a coronavirus infection. For example, treatment may be effected by administering a neurotransmitter inhibitor, a signaling kinase inhibitor, an estrogen receptor inhibitor, a DNA metabolism inhibitor or an anti-parasitic agent. Also provided are methods for treating a coronavirus infection in which an anti-viral drug also is administered during any of the described methods.
    Type: Grant
    Filed: April 7, 2015
    Date of Patent: October 8, 2019
    Assignees: University of Maryland, Baltimore, United States Government as represented by the Secretary, Department of Health and Human Services
    Inventors: Matthew Frieman, Peter B. Jarhling, Lisa E. Hensley
  • Methods of Treating Coronavirus Infection
    Publication number: 20170027975
    Abstract: The present invention provides methods for treating a coronavirus infection. For example, treatment may be effected by administering a neurotransmitter inhibitor, a signaling kinase inhibitor, an estrogen receptor inhibitor, a DNA metabolism inhibitor or an anti-parasitic agent. Also provided are methods for treating a coronavirus infection in which an anti-viral drug also is administered during any of the described methods.
    Type: Application
    Filed: April 7, 2015
    Publication date: February 2, 2017
    Applicants: University of Maryland, Baltimore, United States Government as represented by the Secretary, Department of Health and Human Services
    Inventors: Matthew Frieman, Peter B. Jarhling, Lisa E. Hensley