Abstract: Wet-mixing process, electrically-conductive fused deposition modeling material, 3D printable fused deposition modeling (FDM) filament, electrically-conductive ink, and associated methods. A wet mixing process includes dissolving a thermoplastic with a solvent, thereby creating a thermoplastic-based solution, suspending conductive carbon nanofibers (CNFs) in the thermoplastic-based solution, and mixing the thermoplastic-based solution to distribute the CNFs throughout the solution. The solvent may be evaporated from thermoplastic-based solution to form an electrically-conductive FDM material having a solid matrix of the thermoplastic with CNFs dispersed homogenously throughout the solid matrix. A 3D printable fused deposition modeling filament may be formed of the FDM material. An electrical circuit component may be additively manufactured with a 3D printer and the FDM material. An electrically-conductive ink may be formed from the thermoplastic-based solution.

Abstract: The disclosure relates to a compound of formula wherein Y, X, Ra, Rb, R1 and R2 are defined herein, PVC compositions comprising the compounds disclosed herein, as well as methods for modulating properties of a PVC, including reducing or preventing the formation of observable gas checks in calendered films, or other mechanical properties such as tensile strength and/or glass transition temperature.

Abstract: A method of forming a cushioning element. The method including placing a first sheet adjacent to an outer surface of a first mold portion, the first mold portion including a first mold cavity. The method including pressing a portion of the first sheet into the first mold portion and into the first mold cavity with a forming tool, wherein at least a portion of the forming tool is extended into the first mold cavity. The method including applying negative pressure to the first mold cavity to draw the portion of the first sheet into the first mold cavity, and joining a second sheet to the first sheet to form the cushioning element.

Abstract: The present invention relates to compounds of formula I: in which p, q, Y1, Y2, R1, R2a, R2b, R3a, R3b, R4a, R4b, R5a, R5b, R7 and R8 are defined in the Summary of the Invention; capable of inhibiting the activity of SHP2. The invention further provides a process for the preparation of compounds of the invention, pharmaceutical preparations comprising such compounds and methods of using such compounds and compositions in the management of diseases or disorders associated with the aberrant activity of SHP2.

Abstract: A non-limiting embodiment of a titanium alloy comprises, in weight percentages based on total alloy weight: 2.0 to 5.0 aluminum; 3.0 to 8.0 tin; 1.0 to 5.0 zirconium; 0 to a total of 16.0 of one or more elements selected from the group consisting of oxygen, vanadium, molybdenum, niobium, chromium, iron, copper, nitrogen, and carbon; titanium; and impurities. A non-limiting embodiment of the titanium alloy comprises an intentional addition of tin and zirconium in conjunction with certain other alloying additions such as aluminum, oxygen, vanadium, molybdenum, niobium, and iron, to stabilize the ? phase and increase the volume fraction of the ? phase without the risk of forming embrittling phases, which was observed to increase room temperature tensile strength while maintaining ductility.

Abstract: An apparatus and method are provided for storing a plurality of translation entries in a cache, each translation entry corresponding to one of a plurality of page table entries and defining a translation between a first address and a second address, and encoding control information indicative of an attribute of each page table entry; returning, in response to a lookup querying a first lookup address, a corresponding second address when the first lookup address corresponds to one of the plurality of translation entries stored in the cache; modifying at least some of the control information in response to notification of a modification of the attribute in a page table entry; and retaining in the cache at least one translation entry corresponding to the page table entry for use in a subsequent address lookup querying a corresponding first lookup address in response to the notification of the modification of the attribute in the page table entry.

Abstract: A modular enclosure system and method for repair of one or more leaks in a pipe. The modular enclosure system including a first enclosure portion configured to be disposed in a mated configuration to create a first enclosure around the pipe. Each enclosure includes a first void section configured to enclose a pipe section of the pipe. Sealant grooves extend along enclosure faces of each enclosure to seal the modular enclosure system. Each enclosure includes a sealant control system having a plurality of blocking members and configured to selectively block sealant injected in the sealant grooves. Each of the blocking members are positionable between a blocking position configured to block sealant flow in at least one of the sealant grooves and a non-blocking position.

Abstract: A method and apparatus for performing refactored multiply-and-accumulate operations is provided. A summing array includes a plurality of non-volatile memory elements arranged in columns. Each non-volatile memory element in the summing array is programmed to a high resistance state or a low resistance state based on weights of a neural network. The summing array is configured to generate a summed signal for each column based, at least in part, on a plurality of input signals. A multiplying array is coupled to the summing array, and includes a plurality of non-volatile memory elements. Each non-volatile memory element in the multiplying array is programmed to a different conductance level based on the weights of the neural network. The multiplying array is configured to generate an output signal based, at least in part, on the summed signals from the summing array.

Abstract: Systems and methods are disclosed that provide smart alerts to users, e.g., alerts to users about diabetic states that are only provided when it makes sense to do so, e.g., when the system can predict or estimate that the user is not already cognitively aware of their current condition, e.g., particularly where the current condition is a diabetic state warranting attention. In this way, the alert or alarm is personalized and made particularly effective for that user. Such systems and methods still alert the user when action is necessary, e.g., a bolus or temporary basal rate change, or provide a response to a missed bolus or a need for correction, but do not alert when action is unnecessary, e.g., if the user is already estimated or predicted to be cognitively aware of the diabetic state warranting attention, or if corrective action was already taken.

Abstract: Disclosed is an arrangement including a staircase as well as walkway systems. The staircase includes a transitional member, and the walkways incorporate grate supports in order to facilitate the connection to adjacent structures. The arrangement also utilizes angled members which are configured with a reinforced flange existing in a dimension that has higher load requirements than the other flange. A novel step configuration is also disclosed.

Abstract: Disclosed is an arrangement including a staircase as well as walkway systems. The staircase includes a transitional member, and the walkways incorporate grate supports in order to facilitate the connection to adjacent structures. The arrangement also utilizes angled members which are configured with a reinforced flange existing in a dimension that has higher load requirements than the other flange. A novel step configuration is also disclosed.

Abstract: Disclosed is an arrangement including a staircase as well as walkway systems. The staircase includes a transitional member, and the walkways incorporate grate supports in order to facilitate the connection to adjacent structures. The arrangement also utilizes angled members which are configured with a reinforced flange existing in a dimension that has higher load requirements than the other flange. A novel step configuration is also disclosed.

Abstract: Disclosed is an arrangement including a staircase as well as walkway systems. The staircase includes a transitional member, and the walkways incorporate grate supports in order to facilitate the connection to adjacent structures. The arrangement also utilizes angled members which are configured with a reinforced flange existing in a dimension that has higher load requirements than the other flange. A novel step configuration is also disclosed.

Abstract: Aspects of the present invention provide novel compositions and methods based on novel calpastatin (CAST) genetic markers, such as missense mutations in exon 3 that result in G48D or P52L substitutions (NM_174003.2:c.271G>A and 283C>T), a G/T substitution in intron 3 (AAFC02060381.1:g.2110G>T) and a GAAA repeat in intron 8 (AAFC02060381.1:g.6700[(GAAA)4]+[(GAAA)5]. Particular aspects provide novel markers for fertility (e.g., daughter pregnancy rate, DPR) and longevity (e.g., productive life, PL) in, for example, dairy cattle. Additional aspects provide for novel methods comprising marker-assisted selection to improve fertility and/or longevity in dairy cattle. Therefore, in particular embodiments, a combination of genetic selection based on one or more of the novel CAST markers, and high PTA potentials of milk production traits, provides for improved reproductive traits in association with continued high milk production traits.