Patents by Inventor Matthew Graneto

Matthew Graneto has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PYRAZOLE COMPOUNDS AS PROTEIN KINASE INHIBITORS
    Publication number: 20080113971
    Abstract: Compounds are described which inhibit mitogen activated protein kinase-activated protein kinase-2 (MK-2). Methods of making such compounds are described, as well as a method of using them for the inhibition of MK-2, and for the prevention or treatment of a disease or disorder that is mediated by TNF?, where the method involves administering to the subject an MK-2 inhibiting compound of the present invention. Pharmaceutical compositions and kits which contain the present MK-2 inhibiting compounds are also described.
    Type: Application
    Filed: December 17, 2007
    Publication date: May 15, 2008
    Inventors: Cathleen Hanau, Serena Mershon, Matthew Graneto, Marvin Meyers, Ingrid Buchler, Shridhar Hegde, Kun Wu, Shuang Liu
  • Substituted pyrazoles as p38 kinase inhibitors
    Publication number: 20070078146
    Abstract: A class of pyrazole derivatives is described for use in treating p38 kinase medicated disorders. Compounds of particular interest are defined by Formula IA wherein R1, R2, R3 and R4 are as described in the specification.
    Type: Application
    Filed: May 5, 2004
    Publication date: April 5, 2007
    Inventors: Ashok Naraian, Michael Clare, Paul Collins, Joyce Crich, Rajesh Devraj, Daniel Flynn, Lifeng Geng, Matthew Graneto, Cathleen Hanau, Gunnar Hanson, Susan Hartmann, Michael Hepperle, He Huang, Ish Khanna, Francis Koszyk, Shuyuan Liao, Suzanne Metz, Win Naing, Richard Partis, Thao Perry, Shashidhar Rao, Shaun Selness, Michael South, Michael Stealey, John Talley, Michael Vazquez, John Walker, Richard Weier, Xiangdong Xu, Syaulan Yang, Yi Yu
  • Substituted pyrazolyl benzenesulfonamides for the treatment of inflamation
    Publication number: 20050131050
    Abstract: A class of pyrazolyl benzenesulfonamide compounds is described for use in treating inflammation and inflammation-related disorders.
    Type: Application
    Filed: January 31, 2005
    Publication date: June 16, 2005
    Applicant: G.D. Searle & Co.
    Inventors: John Talley, Thomas Penning, Paul Collins, Donald Rogier, James Malecha, Julie Miyashiro, Stephen Bertenshaw, Ish Khanna, Matthew Graneto, Roland Rogers, Jeffery Carter, Stephen Docter, Stella Yu
  • Substituted benzopyran derivatives for the treatment of inflammation
    Publication number: 20050049252
    Abstract: A class of benzopyran, derivatives is described for use in treating cyclooxygenase-2 mediated disorders. Compounds of particular interest are defined by Formula I? wherein X, A1, A2, A3, A4, R, R?, R1 and R2 are as described in the specification.
    Type: Application
    Filed: August 19, 2004
    Publication date: March 3, 2005
    Applicant: G.D. Searle & Co.
    Inventors: Jeffery Carter, Mark Obukowicz, Balekudru Devadas, John Talley, David Brown, Matthew Graneto, Stephen Bertenshaw, Donald Rogier, Srinivasan Nagarajan, Cathleen Hanau, Susan Hartmann, Cindy Ludwig, Suzanne Metz, Donald Korte
  • Process for preparing prodrugs of benzenesulfonamide-containing COX-2 inhibitors
    Publication number: 20050032851
    Abstract: Prodrugs of COX-2 inhibitors are described as being useful in treating inflammation and inflammation-related disorders.
    Type: Application
    Filed: September 13, 2004
    Publication date: February 10, 2005
    Inventors: John Talley, James Malecha, Stephen Bertenshaw, Matthew Graneto, Jeffery Carter, Jinglin Li, Srinivasan Nagarajan, David Brown, Donald Rogier, Thomas Penning, Ish Khanna, Xiangdong Xu, Richard Weier