Patents by Inventor Matthew Hassink

Matthew Hassink has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Tetrazine-trans-cyclooctene ligation for the rapid construction of radionuclide labeled probes
    Patent number: 10434197
    Abstract: A Diels-Alder adduct of a trans-cyclooctene with a tetrazine is provided, wherein the adduct bears a substituent labeled with a radionuclide. A method of producing a PET or other image of an organ in an animal or human includes forming the Diels-Alder adduct in the animal or human. Trans-cyclooctenes and tetrazines suitable for preparing the adducts are provided.
    Type: Grant
    Filed: July 21, 2011
    Date of Patent: October 8, 2019
    Assignees: University of Delaware, University of Southern California
    Inventors: Joseph M. Fox, Matthew Hassink, Melissa Blackman, Zibo Li, Peter S. Conti, Ramajeyam Selvaraj
  • Tetrazine-trans-cyclooctene Ligation for the Rapid Construction of Radionuclide Labeled Probes
    Publication number: 20130266512
    Abstract: A Diels-Alder adduct of a trans-cyclooctene with a tetrazine is provided, wherein the adduct bears a substituent labeled with a radionuclide. A method of producing a PET or other image of an organ in an animal or human includes forming the Diels-Alder adduct in the animal or human. Trans-cyclooctenes and tetrazines suitable for preparing the adducts are provided.
    Type: Application
    Filed: July 21, 2011
    Publication date: October 10, 2013
    Applicants: University of Southern California, University of Delaware
    Inventors: Joseph M. Fox, Matthew Hassink, Melissa Blackman, Zibo Li, Peter S. Conti, Ramajeyam Selvaraj