Abstract: Relief or prophylaxis from nausea and/or emesis are provided by transdermal compositions comprising dexamethasone and promethazine. The transdermal compositions are in the form of transdermal solutions and/or suspensions, such as lotions, pastes, gels, ointments or transdermal patches.

Abstract: A pharmaceutical composition including a therapeutic does of an active ingredient susceptible of either intentional or accidental misuse by over-utilization and a sub-therapeutic dose of a compound in an amount sufficient to elicit an undesirable response if the recommended therapeutic dose of the active ingredient is exceeded. A multiple dose pharmaceutical dosage form including an effective amount of an active ingredient for a patient in need of treatment thereof and a urine indicator capable of changing the color of the patient's urine when a desired dosage of the active ingredient is exceeded by ingestion of multiple doses in excess of a desired treatment regimen.

Abstract: A pharmaceutical composition including a therapeutic dose of an active ingredient susceptible of either intentional or accidental misuse by over-utilization and a sub-therapeutic dose of a compound in an amount sufficient to elicit an undesirable response if the recommended therapeutic dose of the active ingredient is exceeded.