Abstract: In general, the present disclosure is directed to systems and methods of evaluating a subject's risk of one or more complications associated with pelvic organ prolapse surgery. The method comprising: obtaining, by a computing system comprising one or more computing devices, sample data associated with the subject; obtaining, by a computing system comprising one or more computing devices, medical record data associated with the subject; inputting, by the computing system, the sample data into a machine-learned surgical model; receiving, by the computing system as an output of the machine-learned surgical model, one or more predictions of post-surgical complications of mesh exposure through a vaginal wall associated with the subject; and performing a pelvic organ prolapse repair surgery on the subject.

Abstract: In general, the present disclosure is directed to systems and methods of evaluating a subject's risk of one or more complications associated with pelvic organ prolapse surgery. The method comprising: obtaining, by a computing system comprising one or more computing devices, sample data associated with the subject; inputting, by the computing system, the sample data into a machine-learned immune response model; receiving, by the computing system as an output of the machine-learned immune response model, one or more predictions of post-surgical complications of mesh exposure through the vaginal wall associated with the subject; and performing a pelvic organ prolapse repair surgery on the subject, wherein the surgery is performed based at least in part on the one or more predictions of post-surgical complications by the machine-learned immune response model associated with a likelihood of success.

Abstract: Wheelchair designs and enhancements are provided for use with conventional wheelchair designs. The designs and enhancements include first and second contoured folding seat panels that are hingedly mounted with respect to the wheelchair frame and that are offer interlocking functionality. The folding seats generally provide contouring in both front-to-back and side-to-side directions. Features are provided to prevent capture of objects between seat panels as they are brought into interlocking engagement. Pivotal footrests that offer enhanced stability in the form of lateral, front-to-back and up-down stability are provided In addition, axle and axle plate combinations are described that provide enhanced flexibility in relative positioning with respect to the wheelchair frame. The disclosed features and functionalities may be incorporated into wheelchair designs, either in whole or in part, to provide enhanced user interaction with the wheelchair.

Abstract: Polymer blends of glycolide and/or lactide homopolymer and/or glycolide/lactide copolymer and polycaprolactone and/or polytrimethylene carbonate homopolymer or copolymers thereof and absorbable surgical devices manufactured therefrom having improved mechanical properties, such as improved impact resistance and improved cyclic flex, are disclosed.

Abstract: Polymer blends of glycolide and/or lactide homopolymer and/or glycolide/lactide copolymer and polycaprolactone and/or polytrimethylene carbonate homopolymer or copolymers thereof and absorbable surgical devices manufactured therefrom having improved mechanical properties, such as improved impact resistance and improved cyclic flex, are disclosed. The blends may be prepared by polymerizing a glycolide or lactide containing polymer in the presence of a polymer derived from trimethylene carbonate or .epsilon.-caprolactone.

Abstract: Polymer blends of glycolide and/or lactide homopolymer and/or glycolide/lactide copolymer and polycaprolactone and/or polytrimethylene carbonate homopolymer or copolymers thereof and absorbable surgical devices manufactured therefrom having improved mechanical properties, such as improved impact resistance and improved cyclic flex, are disclosed.