Patents by Inventor Matthew Hill
Matthew Hill has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11911767Abstract: Described are exemplary embodiments of a syringe identification system for use with a positive displacement pipette, such as a handheld powered positive displacement pipette. An exemplary syringe identification system may include a sensor, such as a color sensor, that is located at or near a distal end of the pipette and arranged such that the sensor is operative to read an identifying marking(s) on a syringe that has been installed to the pipette. The sensor may be a color sensor having an illumination source and configured to read a color code on the syringe. The color code may be usable to identify the syringe to the pipette.Type: GrantFiled: October 25, 2019Date of Patent: February 27, 2024Assignee: Mettler-Toledo Rainin, LLCInventors: Richard Hill, Michael McNaul, Bob Wells, Simon Shakespeare, Matthew Newman
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Publication number: 20240060124Abstract: Methods for non-invasive prenatal paternity testing are disclosed herein. The method uses genetic measurements made on plasma taken from a pregnant mother, along with genetic measurements of the alleged father, and genetic measurements of the mother, to determine whether or not the alleged father is the biological father of the fetus. This is accomplished by way of an informatics based method that can compare the genetic fingerprint of the fetal DNA found in maternal plasma to the genetic fingerprint of the alleged father.Type: ApplicationFiled: July 28, 2023Publication date: February 22, 2024Applicant: Natera, Inc.Inventors: Allison Ryan, Styrmir Sigurjonsson, Milena Banjevic, George Gemelos, Matthew Hill, Johan Baner, Matthew Rabinowitz, Zachary Demko
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Publication number: 20240062846Abstract: The present disclosure provides methods for determining the ploidy status of a chromosome in a gestating fetus from genotypic data measured from a mixed sample of DNA comprising DNA from both the mother of the fetus and from the fetus, and optionally from genotypic data from the mother and father. The ploidy state is determined by using a joint distribution model to create a plurality of expected allele distributions for different possible fetal ploidy states given the parental genotypic data, and comparing the expected allelic distributions to the pattern of measured allelic distributions measured in the mixed sample, and choosing the ploidy state whose expected allelic distribution pattern most closely matches the observed allelic distribution pattern. The mixed sample of DNA may be preferentially enriched at a plurality of polymorphic loci in a way that minimizes the allelic bias, for example using massively multiplexed targeted PCR.Type: ApplicationFiled: September 21, 2023Publication date: February 22, 2024Applicant: Natera, Inc.Inventors: Matthew RABINOWITZ, George GEMELOS, Milena BANJEVIC, Allison RYAN, Zachary DEMKO, Matthew HILL, Bernhard ZIMMERMANN, Johan BANER
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Publication number: 20240038328Abstract: The present disclosure provides methods for determining the ploidy status of a chromosome in a gestating fetus from genotypic data measured from a mixed sample of DNA comprising DNA from both the mother of the fetus and from the fetus, and optionally from genotypic data from the mother and father. The ploidy state is determined by using a joint distribution model to create a plurality of expected allele distributions for different possible fetal ploidy states given the parental genotypic data, and comparing the expected allelic distributions to the pattern of measured allelic distributions measured in the mixed sample, and choosing the ploidy state whose expected allelic distribution pattern most closely matches the observed allelic distribution pattern. The mixed sample of DNA may be preferentially enriched at a plurality of polymorphic loci in a way that minimizes the allelic bias, for example using massively multiplexed targeted PCR.Type: ApplicationFiled: September 21, 2023Publication date: February 1, 2024Applicant: Natera, Inc.Inventors: Matthew RABINOWITZ, George GEMELOS, Milena BANJEVIC, Allison RYAN, Zachary DEMKO, Matthew HILL, Bernhard ZIMMERMANN, Johan BANER
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Publication number: 20240035309Abstract: A vertical door latch assembly includes a housing and a bolt movably attached to the housing having a catch portion. A drive motor is located within the housing and is configured to selectively move a lock assembly between a locked position preventing movement of the bolt and an unlocked position allowing movement of the bolt. A controller is in electrical communication with the drive motor and is configured to direct the actuator lock assembly between the locked position and the unlocked position.Type: ApplicationFiled: October 11, 2023Publication date: February 1, 2024Inventors: Jon Marc Luebeck, Anthony Pettigrew, Matthew Hill, Eric Chang, Christopher Marks, Patrick Sweeney
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Publication number: 20240007025Abstract: An aircraft includes an internal combustion engine and an electrical power system. The electrical power system includes a permanent magnet machine and an inverter coupled to the permanent magnet machine. The permanent magnet machine includes a stator and a rotor configured to rotate relative to the stator.Type: ApplicationFiled: May 27, 2022Publication date: January 4, 2024Inventors: David R. Trawick, Matthew Hill, Chandana J. Gajanayake
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Patent number: 11859410Abstract: A vertical door latch assembly includes a housing and a bolt movably attached to the housing having a catch portion. A drive motor is located within the housing and is configured to selectively move a lock assembly between a locked position preventing movement of the bolt and an unlocked position allowing movement of the bolt. A controller is in electrical communication with the drive motor and is configured to direct the actuator lock assembly between the locked position and the unlocked position.Type: GrantFiled: August 21, 2020Date of Patent: January 2, 2024Assignee: Carrier CorporationInventors: Jon Marc Luebeck, Anthony Pettigrew, Matthew Hill, Eric Chang, Christopher Marks, Patrick Sweeney
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Publication number: 20230420071Abstract: The present disclosure provides methods for determining the ploidy status of a chromosome in a gestating fetus from genotypic data measured from a mixed sample of DNA comprising DNA from both the mother of the fetus and from the fetus, and optionally from genotypic data from the mother and father. The ploidy state is determined by using a joint distribution model to create a plurality of expected allele distributions for different possible fetal ploidy states given the parental genotypic data, and comparing the expected allelic distributions to the pattern of measured allelic distributions measured in the mixed sample, and choosing the ploidy state whose expected allelic distribution pattern most closely matches the observed allelic distribution pattern. The mixed sample of DNA may be preferentially enriched at a plurality of polymorphic loci in a way that minimizes the allelic bias, for example using massively multiplexed targeted PCR.Type: ApplicationFiled: September 7, 2023Publication date: December 28, 2023Applicant: Natera, Inc.Inventors: Matthew RABINOWITZ, George GEMELOS, Milena BANJEVIC, Allison RYAN, Zachary DEMKO, Matthew HILL, Bernhard ZIMMERMANN, Johan BANER
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Patent number: 11846120Abstract: A vertical door latch assembly includes a housing and a bolt movably attached to the housing having a catch portion. A drive motor is located within the housing and is configured to selectively move a lock assembly between a locked position preventing movement of the bolt and an unlocked position allowing movement of the bolt. A battery assembly is removable from the housing when the lock assembly is in first position and fixed to the housing when the lock assembly is in a second position. A controller is in electrical communication with the drive motor and is configured to direct the actuator lock assembly between the locked position and the unlocked position.Type: GrantFiled: August 21, 2020Date of Patent: December 19, 2023Assignee: Carrier CorporationInventors: Matthew Hill, Anthony Pettigrew, Eric Chang, Christopher Marks, Patrick Sweeney
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Publication number: 20230399636Abstract: The present disclosure provides methods and compositions for cell free cloning and polynucleotide production. In illustrative aspects, the methods of the present disclosure comprise the use of molecular barcodes and a dilution step. Moreover, some aspects of the instant disclosure relate to systems and kits comprising molecular barcodes for use with methods of cell free cloning and polynucleotide production.Type: ApplicationFiled: June 16, 2023Publication date: December 14, 2023Inventor: Matthew Hill
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Patent number: 11833882Abstract: A method and system for utilizing environmental data are described. The method includes receiving external environmental data and receiving in-cabin environmental data. A mitigation action for an in-cabin environment of a vehicle is provided. The mitigation action is based on the external environmental data and the in-cabin environmental data.Type: GrantFiled: January 27, 2020Date of Patent: December 5, 2023Assignee: Aclima Inc.Inventors: Robert Murphy, Meghan Elizabeth Thurlow, Melissa M. Lunden, Davida Herzl, Matthew Hill
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Publication number: 20230383348Abstract: The invention provides methods for simultaneously amplifying multiple nucleic acid regions of interest in one reaction volume as well as methods for selecting a library of primers for use in such amplification methods. The invention also provides library of primers with desirable characteristics, such as minimal formation of amplified primer dimers or other non-target amplicons.Type: ApplicationFiled: March 24, 2023Publication date: November 30, 2023Applicant: Natera, Inc.Inventors: Matthew RABINOWITZ, Matthew HILL, Bernhard ZIMMERMANN, George GEMELOS, Johan BANER, Milena BANJEVIC, Allison RYAN, Styrmir SIGURJONSSON, Zachary DEMKO
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Publication number: 20230368865Abstract: The present disclosure provides methods for determining the ploidy status of a chromosome in a gestating fetus from genotypic data measured from a mixed sample of DNA comprising DNA from both the mother of the fetus and from the fetus, and optionally from genotypic data from the mother and father. The ploidy state is determined by using a joint distribution model to create a plurality of expected allele distributions for different possible fetal ploidy states given the parental genotypic data, and comparing the expected allelic distributions to the pattern of measured allelic distributions measured in the mixed sample, and choosing the ploidy state whose expected allelic distribution pattern most closely matches the observed allelic distribution pattern. The mixed sample of DNA may be preferentially enriched at a plurality of polymorphic loci in a way that minimizes the allelic bias, for example using massively multiplexed targeted PCR.Type: ApplicationFiled: July 27, 2023Publication date: November 16, 2023Applicant: Natera, Inc.Inventors: Matthew RABINOWITZ, George GEMELOS, Milena BANJEVIC, Allison RYAN, Zachary DEMKO, Matthew HILL, Bernhard ZIMMERMANN, Johan BANER
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Publication number: 20230360723Abstract: The present disclosure provides methods for determining the ploidy status of a chromosome in a gestating fetus from genotypic data measured from a mixed sample of DNA comprising DNA from both the mother of the fetus and from the fetus, and optionally from genotypic data from the mother and father. The ploidy state is determined by using a joint distribution model to create a plurality of expected allele distributions for different possible fetal ploidy states given the parental genotypic data, and comparing the expected allelic distributions to the pattern of measured allelic distributions measured in the mixed sample, and choosing the ploidy state whose expected allelic distribution pattern most closely matches the observed allelic distribution pattern. The mixed sample of DNA may be preferentially enriched at a plurality of polymorphic loci in a way that minimizes the allelic bias, for example using massively multiplexed targeted PCR.Type: ApplicationFiled: July 27, 2023Publication date: November 9, 2023Applicant: Natera, Inc.Inventors: Matthew RABINOWITZ, George GEMELOS, Milena BANJEVIC, Allison RYAN, Zachary DEMKO, Matthew HILL, Bernhard ZIMMERMANN, Johan BANER
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Publication number: 20230343411Abstract: The present disclosure provides methods for determining the ploidy status of a chromosome in a gestating fetus from genotypic data measured from a mixed sample of DNA comprising DNA from both the mother of the fetus and from the fetus, and optionally from genotypic data from the mother and father. The ploidy state is determined by using a joint distribution model to create a plurality of expected allele distributions for different possible fetal ploidy states given the parental genotypic data, and comparing the expected allelic distributions to the pattern of measured allelic distributions measured in the mixed sample, and choosing the ploidy state whose expected allelic distribution pattern most closely matches the observed allelic distribution pattern. The mixed sample of DNA may be preferentially enriched at a plurality of polymorphic loci in a way that minimizes the allelic bias, for example using massively multiplexed targeted PCR.Type: ApplicationFiled: July 10, 2023Publication date: October 26, 2023Applicant: Natera, Inc.Inventors: Matthew RABINOWITZ, George GEMELOS, Milena BANJEVIC, Allison RYAN, Zachary DEMKO, Matthew HILL, Bernhard ZIMMERMANN, Johan BANER
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Publication number: 20230304319Abstract: A door latch assembly includes a housing; a bolt configured to the extend from the housing in a first direction and retract into the housing in a second direction; a handle connected to the bolt; a lockable, blocking member configured to prevent movement of the bolt; a controller configured to place the door latch assembly into an overlock mode; an actuator in communication with the controller, the actuator configured to prevent movement of the bolt in the overlock mode.Type: ApplicationFiled: March 21, 2023Publication date: September 28, 2023Inventors: Adam Kuenzi, Thomas Grinter, Jon Luebeck, Matthew Hill
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Patent number: 11746376Abstract: Methods for non-invasive prenatal paternity testing are disclosed herein. The method uses genetic measurements made on plasma taken from a pregnant mother, along with genetic measurements of the alleged father, and genetic measurements of the mother, to determine whether or not the alleged father is the biological father of the fetus. This is accomplished by way of an informatics based method that can compare the genetic fingerprint of the fetal DNA found in maternal plasma to the genetic fingerprint of the alleged father.Type: GrantFiled: February 20, 2020Date of Patent: September 5, 2023Assignee: Natera, Inc.Inventors: Matthew Rabinowitz, Matthew Hill, Bernhard Zimmermann, Johan Baner, George Gemelos, Milena Banjevic, Allison Ryan, Styrmir Sigurjonsson, Zachary Demko
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Publication number: 20230215250Abstract: Methods and apparatuses are disclosed that allow an electronic device to autonomously adapt one or more user alerts of the electronic device. For example, some embodiments may include a method for operating a haptic device including driving a haptic device using a control signal, measuring a frequency related to the operation of the haptic device and comparing the measured frequency with a target frequency. A control signal is adjusted based on the comparison to drive the haptic device to the target frequency.Type: ApplicationFiled: March 13, 2023Publication date: July 6, 2023Inventor: Matthew Hill
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Patent number: 11679768Abstract: Methods, systems, and computer readable mediums for determining a scene representation for a vehicle are provided. A disclosed method includes acquiring data from one or more sensors of the vehicle. The method further includes detecting, using processing circuitry, one or more objects in a surrounding of the vehicle based on the acquired data; determining whether an object of the detected one or more objects intersects with a vehicle lane of travel; determining whether the object is in a lane of travel of the vehicle; determining inter-vehicle gaps and cut-ins between the object and the vehicle; and rendering a scene representation including the inter-vehicle gaps and cut-ins between the object and the vehicle.Type: GrantFiled: October 19, 2020Date of Patent: June 20, 2023Assignee: TOYOTA MOTOR ENGINEERING & MANUFACTURING NORTH AMERICA, INC.Inventors: Ryan M. Wiesenberg, Colin Das, Matthew Hill, Emily Lerner, William Fanelli
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Patent number: 11605273Abstract: Methods and apparatuses are disclosed that allow an electronic device to autonomously adapt one or more user alerts of the electronic device. For example, some embodiments may include a method for operating a haptic device including driving a haptic device using a control signal, measuring a frequency related to the operation of the haptic device and comparing the measured frequency with a target frequency. A control signal is adjusted based on the comparison to drive the haptic device to the target frequency.Type: GrantFiled: June 17, 2021Date of Patent: March 14, 2023Assignee: Apple Inc.Inventor: Matthew Hill