Abstract: An amphibious vehicle having a frame that includes a plurality of floatable members. Mounted to the frame is one or more power sources. Also mounted to the frame and connected to the power source are a plurality of propellers with each of the plurality of propellers having a thrust vector configured to be adjusted to provide agitation and propulsion. In addition, mounted to the frame are a plurality of ground engaging devices and one or more pumps.

Abstract: Provided herein is a fusion protein, expression vector, nucleic acid, or method of making and using a first HLA-G monomer and a second HLA-G monomer connected by a linker peptide expressed as a single chain, and optionally, comprising a providence virus globulin domain to prevent or reduce neovascularization.

Abstract: An amphibious vehicle having a frame that includes a plurality of floatable members. Mounted to the frame is one or more power sources. Also mounted to the frame and connected to the power source are a plurality of propellers with each of the plurality of propellers having a thrust vector configured to be adjusted to provide agitation and propulsion. In addition, mounted to the frame are a plurality of ground engaging devices and one or more pumps.

Abstract: An amphibious vehicle having a frame that includes a plurality of floatable members. Mounted to the frame is one or more power sources. Also mounted to the frame and connected to the power source are a plurality of propellers with each of the plurality of propellers having a thrust vector configured to be adjusted to provide agitation and propulsion. In addition, mounted to the frame are a plurality of ground engaging devices and one or more pumps.

Abstract: This invention relates to methods and compositions for gene therapy. In particular, the invention relates to methods and compositions for modulating transgene expression from transgene delivery vectors by recruiting epigenetic modifiers to the vector. Using these methods, transgene delivery vectors can be more precisely regulated to produce increased amounts of the transgene product when needed and to decrease expression when needed, thereby providing maximum benefits for gene therapy while minimizing toxicity.

Abstract: An amphibious vehicle having a frame that includes a plurality of floatable members. Mounted to the frame is one or more power sources. Also mounted to the frame and connected to the power source are a plurality of propellers with each of the plurality of propellers having a thrust vector configured to be adjusted to provide agitation and propulsion. In addition, mounted to the frame are a plurality of ground engaging devices and one or more pumps.

Abstract: An amphibious vehicle having a frame that includes a plurality of floatable members. Mounted to the frame is one or more power sources. Also mounted to the frame and connected to the power source are a plurality of propellers with each of the plurality of propellers having a thrust vector configured to be adjusted to provide agitation and propulsion. In addition, mounted to the frame are a plurality of ground engaging devices and one or more pumps.

Abstract: An amphibious vehicle having a frame that includes a plurality of floatable members. Mounted to the frame is one or more power sources. Also mounted to the frame and connected to the power source are a plurality of propellers with each of the plurality of propellers having a thrust vector configured to be adjusted to provide agitation and propulsion. In addition, mounted to the frame are a plurality of ground engaging devices and one or more pumps.

Abstract: An amphibious vehicle having a frame that includes a plurality of floatable members. Mounted to the frame is one or more power sources. Also mounted to the frame and connected to the power source are a plurality of propellers with each of the plurality of propellers having a thrust vector configured to be adjusted to provide agitation and propulsion. In addition, mounted to the frame are a plurality of ground engaging devices and one or more pumps.

Abstract: An amphibious vehicle having a frame that includes a plurality of floatable members. Mounted to the frame is one or more power sources. Also mounted to the frame and connected to the power source are a plurality of propellers with each of the plurality of propellers having a thrust vector configured to be adjusted to provide agitation and propulsion. In addition, mounted to the frame are a plurality of ground engaging devices and one or more pumps.

Abstract: A carrier for a sample of highly polarized material includes a shell having a radially exterior surface and a radially interior surface, and a sample of highly polarized material interiorly adjacent to the radially interior surface. The shell may be substantially cylindrical, and may be constructed from a magnetic or non-magnetic material. The sample of highly polarized material may comprise a methyl rotor group material. The sample of highly polarized material may comprise pyruvic acid or an acetic acid. The sample of highly polarized material may be co-axial with the cylindrical shell. The sample of highly polarized material may be bonded or frozen to the radially interior surface of the shell. The carrier may further comprise a wad of material that forms a volume and contacts an axially proximate end of at least one of the shell or the sample.

Abstract: A sample polarization system comprises an input stage that includes a sample input port configured and arranged to receive and to provide a sample molecule carrier, and cool the sample molecule carrier from a first temperature to a second temperature as it travels along a length of the input stage, and provides the sample molecule carrier at a input stage output. A closed volume having an interior receives the sample molecule carrier from the input stage output and holds a plurality of sample molecule carriers in the high magnetic field created by a magnet adjacent to the closed volume, and outputs the sample molecule carrier from a closed volume output port.

Abstract: A sample polarization system comprises an input stage that includes a sample input port configured and arranged to receive and to provide a sample molecule carrier, and cool the sample molecule carrier from a first temperature to a second temperature as it travels along a length of the input stage, and provides the sample molecule carrier at a input stage output. A closed volume having an interior receives the sample molecule carrier from the input stage output and holds a plurality of sample molecule carriers in the high magnetic field created by a magnet adjacent to the closed volume, and outputs the sample molecule carrier from a closed volume output port. An output stage that includes an output stage input receives the sample molecule carrier from the closed volume output port and warms the sample molecule carrier as it travels from the output stage input to an output stage output to provide a hyperpolarized sample molecule.

Abstract: In exemplary implementations of this invention, light from a light field projector is transmitted through an angle-expanding screen to create a glasses-free, 3D display. The display can be horizontal-only parallax or full parallax. In the former case, a vertical diffuser may positioned in the optical stack. The angle-expanding screen may comprise two planar arrays of optical elements (e.g., lenslets or lenticules) separated from each other by the sum of their focal distances. Alternatively, a light field projector may project light rays through a focusing lens onto a diffuse, transmissive screen. In this alternative approach, the light field projector may comprise two spatial light modulators (SLMs). A focused image of the first SLM, and a slightly blurred image of the second SLM, are optically combined on the diffuser, creating a combined image that has a higher spatial resolution and a higher dynamic range than either of two SLMs.

Abstract: In exemplary implementations of this invention, two LCD screens display a multi-view 3D image that has both horizontal and vertical parallax, and that does not require a viewer to wear any special glasses. Each pixel in the LCDs can take on any value: the pixel can be opaque, transparent, or any shade between. For regions of the image that are adjacent to a step function (e.g., a depth discontinuity) and not adjacent to a sharp corner, the screens display local parallax barriers comprising many small slits. The barriers and the slits tend to be oriented perpendicular to the local angular gradient of the target light field. In some implementations, the display is optimized to seek to minimize the Euclidian distance between the desired light field and the actual light field that is produced. Weighted, non-negative matrix factorization (NMF) is used for this optimization.

Abstract: In exemplary implementations of this invention, two LCD screens display a multi-view 3D image that has both horizontal and vertical parallax, and that does not require a viewer to wear any special glasses. Each pixel in the LCDs can take on any value: the pixel can be opaque, transparent, or any shade between. For regions of the image that are adjacent to a step function (e.g., a depth discontinuity) and not adjacent to a sharp corner, the screens display local parallax barriers comprising many small slits. The barriers and the slits tend to be oriented perpendicular to the local angular gradient of the target light field. In some implementations, the display is optimized to seek to minimize the Euclidian distance between the desired light field and the actual light field that is produced. Weighted, non-negative matrix factorization (NMF) is used for this optimization.

Abstract: In exemplary implementations of this invention, two LCD screens display a multi-view 3D image that has both horizontal and vertical parallax, and that does not require a viewer to wear any special glasses. Each pixel in the LCDs can take on any value: the pixel can be opaque, transparent, or any shade between. For regions of the image that are adjacent to a step function (e.g., a depth discontinuity) and not adjacent to a sharp corner, the screens display local parallax barriers comprising many small slits. The barriers and the slits tend to be oriented perpendicular to the local angular gradient of the target light field. In some implementations, the display is optimized to seek to minimize the Euclidian distance between the desired light field and the actual light field that is produced. Weighted, non-negative matrix factorization (NMF) is used for this optimization.

Abstract: A method includes pneumatically expelling a sample of magnetically polarized material along a pneumatic flow path from a cryogenic environment.

Abstract: In exemplary implementations of this invention, light from a light field projector is transmitted through an angle-expanding screen to create a glasses-free, 3D display. The display can be horizontal-only parallax or full parallax. In the former case, a vertical diffuser may positioned in the optical stack. The angle-expanding screen may comprise two planar arrays of optical elements (e.g., lenslets or lenticules) separated from each other by the sum of their focal distances. Alternatively, a light field projector may project light rays through a focusing lens onto a diffuse, transmissive screen. In this alternative approach, the light field projector may comprise two spatial light modulators (SLMs). A focused image of the first SLM, and a slightly blurred image of the second SLM, are optically combined on the diffuser, creating a combined image that has a higher spatial resolution and a higher dynamic range than either of two SLMs.

Abstract: In exemplary implementations of this invention, an automultiscopic display device includes (1) one or more spatially addressable, light attenuating layers, and (2) a controller which is configured to perform calculations to control the device. In these calculations, tensors provide sparse, memory-efficient representations of a light field. The calculations include using weighted nonnegative tensor factorization (NTF) to solve an optimization problem. The NTF calculations can be sufficiently efficient to achieve interactive refresh rates. Either a directional backlight or a uniform backlight may be used. For example, the device may have (1) a high resolution LCD in front, and (2) a low resolution directional backlight. Or, for example, the device may have a uniform backlight and three or more LCD panels. In these examples, all of the LCDs and the directional backlight (if applicable) may be time-multiplexed.