Patents by Inventor Matthew Holderfield

Matthew Holderfield has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR IDENTIFICATION OF MODULATORS OF RAS PROTEIN COMPLEXES
    Publication number: 20230258642
    Abstract: Provided herein are compositions and methods for detecting conformational changes in a protein using surface-selective techniques in conjunction with a cell-free support interface. The protein generally comprises a lipid tail. The compositions and methods are useful in identifying agents that modify the conformation and activity of such proteins and protein complexes.
    Type: Application
    Filed: June 23, 2022
    Publication date: August 17, 2023
    Inventors: Elizabeth Vo, Matthew Holderfield, Joshua Salafsky