Patents by Inventor Matthew J. Glassman

Matthew J. Glassman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Thermoreversible hydrogels from the arrested phase separation of elastin-like polypeptides
    Patent number: 10517990
    Abstract: Elastin-like polypeptides (ELPs) form hydrogels upon heating. The polypeptides can comprise the generic sequence (XPAVG)n (SEQ ID NO: 4), wherein independently for each occurrence X can be any one of a number of different natural or unnatural amino acids, and n is chosen to determine the size of the protein. Hydrogels comprising the polypeptides have mechanical properties, including elastic modulus and fracture toughness, required for load-bearing applications.
    Type: Grant
    Filed: December 2, 2015
    Date of Patent: December 31, 2019
    Assignee: Massachusetts Institute of Technology
    Inventors: Bradley D. Olsen, Matthew J. Glassman, Reginald K. Avery
  • Thermoreversible Hydrogels From the Arrested Phase Separation of Elastin-Like Polypeptides
    Publication number: 20170049923
    Abstract: Disclosed are elastin-like polypeptides (ELPs) that form hydrogels upon heating. Hydrogels comprising the polypeptides have mechanical properties, including elastic modulus and fracture toughness, required for load-bearing applications.
    Type: Application
    Filed: December 2, 2015
    Publication date: February 23, 2017
    Inventors: Bradley D. Olsen, Matthew J. Glassman, Reginald K. Avery
  • Catechol-rich polymers from N-substituted maleimides
    Patent number: 9540462
    Abstract: Monomers and polymers, and a method of making polymers that retain the ability of the polymer to form reversible and irreversible bonds are provided. Gels comprising the polymers have the ability to coordinate metal ions and bind biopolymers.
    Type: Grant
    Filed: December 7, 2015
    Date of Patent: January 10, 2017
    Assignee: Massachusetts Institute of Technology
    Inventors: Matthew J. Glassman, Bradley D. Olsen
  • CATECHOL-RICH POLYMERS FROM N-SUBSTITUTED MALEIMIDES
    Publication number: 20160194415
    Abstract: Disclosed are monomers, polymers and a method of making polymers that retain the ability of the polymer to from reversible and irreversible bonds. Gels comprising the polymers have the ability to coordinate metal ions and bind biopolymers.
    Type: Application
    Filed: December 7, 2015
    Publication date: July 7, 2016
    Inventors: Matthew J. Glassman, Bradley D. Olsen
  • Nanostructured physically-associating hydrogels for injectable, responsive, and tough biomaterials
    Patent number: 8916683
    Abstract: Described herein are block copolymer conjugates that form double-network hydrogels under appropriate conditions. The conjugates comprise a block of polymer end-group, a block of self-associating peptide or protein, and flexible linkers between the two. Hydrogels comprising the conjugates have the mechanical properties, including elastic modulus and fracture toughness, required for load-bearing applications, while maintaining desirable shear-thinning properties, for example, for injectability.
    Type: Grant
    Filed: October 5, 2011
    Date of Patent: December 23, 2014
    Assignee: Massachusetts Institute of Technology
    Inventors: Bradley D. Olsen, Matthew J. Glassman, Jacqueline Chan
  • Nanostructured Physically-Associating Hydrogels for Injectable, Responsive, and Tough Biomaterials
    Publication number: 20140024722
    Abstract: Described herein are block copolymer conjugates that form double-network hydrogels under appropriate conditions. The conjugates comprise a block of polymer end-group, a block of self-associating peptide or protein, and flexible linkers between the two. Hydrogels comprising the conjugates have the mechanical properties, including elastic modulus and fracture toughness, required for load-bearing applications, while maintaining desirable shear-thinning properties, for example, for injectability.
    Type: Application
    Filed: October 5, 2011
    Publication date: January 23, 2014
    Applicant: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
    Inventors: Bradley D. Olsen, Matthew J. Glassman, Jacqueline Chan