Abstract: The disclosure relates to USP30 Inhibitor Compounds, pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising same, and medical uses involving same.

Abstract: A gas turbine engine article includes a silicon-containing ceramic wall that has an external combustion gaspath side and an internal side that borders a cooling air cavity. The external combustion gaspath side has an associated combustion gas flow direction there along. An array of cooling holes extends through the silicon-containing ceramic wall and connects the internal side with the external combustion gaspath side. The cooling holes are oriented to discharge cooling air to the external gaspath side in a direction counter to the combustion gas flow direction.

Abstract: Various methods and devices are provided for allowing multiple surgical instruments to be inserted into sealing elements of a single surgical access device. The sealing elements can be movable along predefined pathways within the device to allow surgical instruments inserted through the sealing elements to be moved laterally, rotationally, angularly, and vertically relative to a central longitudinal axis of the device for ease of manipulation within a patient's body while maintaining insufflation.

Abstract: A lithium-ion battery assembly configured to provide electric power to a vehicle. The battery assembly includes a plurality of battery cells interconnected to provide a combined electrical potential between positive and negative terminals of the battery assembly, and a printed circuit board assembly (PCBA) disposed adjacent to a first array of battery cells of the plurality of battery cells. The PCBA includes a collector plate electrically coupled with the first array of battery cells, a temperature sensor configured to obtain temperature readings, a plurality of heaters configured to generate heat using electrical power, and an assembly processor. The assembly processor is configured to obtain readings from the temperature sensor, determine an estimated battery cell temperature, and initiate a heating program by delivering electrical power to the plurality of heaters from an electrical power source when the estimated battery cell temperature is below a threshold.

Abstract: A consumer payment control system receives a request to increase a stored value of the consumer account by a credit value, transmits a funding request to a consumer account funding infrastructure, the funding request including a credit value, and increases a stored value of the consumer account by the credit value. A communication and routing module receives a charge request, including an amount and identifies a selected one of the consumer accounts. A transaction processing system processes the charge request based on an account detail of the selected consumer account. The consumer payment control system determines whether a top-up confirmation has been received from the consumer account funding infrastructure after a predetermined period of time, and causes charging of the consumer account if the top-up confirmation has not been received.

Abstract: A consumer payment control system receives a request to increase a stored value of the consumer account by a credit value, transmits a funding request to a consumer account funding infrastructure, the funding request including a credit value, and increases a stored value of the consumer account by the credit value. A communication and routing module receives a charge request, including an amount and identifies a selected one of the consumer accounts. A transaction processing system processes the charge request based on an account detail of the selected consumer account. The consumer payment control system determines whether a top-up confirmation has been received from the consumer account funding infrastructure after a predetermined period of time, and causes charging of the consumer account if the top-up confirmation has not been received.

Abstract: A link system providing a desired spatial relationship in a desired orientation of the link system as well as methods of assembling link systems to obtain the desired spatial relationship. The link system includes at least one rivet deformed during the riveting process to take up the misalignment of apertures in link due to manufacturing tolerance stack up.