Abstract: A system including a computing device, a software application stored in a memory of the computing device and configured to run on a processor of the computing device, and a module in communication with the computing device, said module including a data communication capability, where the data includes light intensity or wavelength information, a light source configured to provide light capable of penetrating the patient's skin to a subcutaneous level, a light sensor configured to detect the light from the light source reflected and scattered from the patient's skin including from the subcutaneous level at a single point in time or sequentially at multiple points in time, and a power source, where the software application is configured to determine levels or concentrations of a substance in a patient's skin based on a measurement of light intensity or wavelength from the light sensor.

Abstract: A drug-delivery device is provided including a drug reservoir configured to contain a fluid drug, a needle cartridge comprising a plurality of needle assemblies, a drive member, a pump, one or more springs, a loading button and a dosing button. The device is configured to use work done by the user in actuating the loading button to load the one or more springs. When the user actuates the dosing button after actuating the loading button, the device is configured to (i) release the one or more loaded springs to operate the drive member to drive a needle assembly that is in operational alignment with the drive member from a retracted position to an injection position, (ii) drive the pump to pump fluid drug from the drug reservoir through the driven needle assembly, and (iii) retract the driven needle assembly from the injection position to the retracted position.

Abstract: A medication delivery device with a sensing system to determine at least one of a dose set and a dose delivery. The sensing system is operable to detect relative rotational positions of first and second members of the device which are indicative of at least one of an amount of a dose set and an amount of a dose delivered by operation of the device, and generate outputs correlated to such relative rotational positions. The system includes a wiper coupled to the first member, and a sensing band coupled to the second member for physically contacting the wiper as the second member rotates relative to the first member. A controller electrically communicates with the sensing system to determine, based on the generated outputs of the sensing system, at least one of the amount of the dose set and the amount of the dose delivered by operation of the device.

Abstract: A rotary sub-assembly for pumping of fluid is provided. The sub-assembly includes a hollow body defining a cavity having a longitudinal axis, the body comprising a cavity wall with at least two ports passing therethrough. At least a portion of the cavity has a non-circular cross-section such that a first constant or varying radial distance from the longitudinal axis to inwardly-offset segments of the cavity wall surrounding the two ports is less than a second constant or varying radial distance from the longitudinal axis to second segments of the cavity wall spaced apart from the two ports. A rotatable plunger is housed in the cavity. The plunger is sized and shaped such that a side wall of the plunger can establish a liquid-tight seal against the inwardly-offset segments of the cavity wall, but does not establish a liquid-tight seal with the second segments of the cavity wall spaced apart from the two ports.

Abstract: A rotary sub-assembly for pumping of fluid is provided. The sub-assembly includes a hollow body defining a cavity having a longitudinal axis, the body comprising a cavity wall with at least two ports passing therethrough. At least a portion of the cavity has a non-circular cross-section such that a first constant or varying radial distance from the longitudinal axis to inwardly-offset segments of the cavity wall surrounding the two ports is less than a second constant or varying radial distance from the longitudinal axis to second segments of the cavity wall spaced apart from the two ports. A rotatable plunger is housed in the cavity. The plunger is sized and shaped such that a side wall of the plunger can establish a liquid-tight seal against the inwardly-offset segments of the cavity wall, but does not establish a liquid-tight seal with the second segments of the cavity wall spaced apart from the two ports.

Abstract: A medication delivery device with a sensing system to determine at least one of a dose set and a dose delivery. The sensing system is operable to detect relative rotational positions of first and second members of the device which are indicative of at least one of an amount of a dose set and an amount of a dose delivered by operation of the device, and generate outputs correlated to such relative rotational positions. The system includes a wiper coupled to the first member, and a sensing band coupled to the second member for physically contacting the wiper as the second member rotates relative to the first member. A controller electrically communicates with the sensing system to determine, based on the generated outputs of the sensing system, at least one of the amount of the dose set and the amount of the dose delivered by operation of the device.

Abstract: The present invention provides a system and method for determining bilirubin levels in an individual based on skin coloration using a smartphone or other personal device and an attached ancillary apparatus. The device, such as a smartphone or tablet, is capable of storing and running software. The device is also coupled to both a camera and light source to obtain data regarding the skin's coloration. Software is installed on the device to control the light source and calculate bilirubin levels in the individual based on the input received from the camera. The ancillary apparatus is a mechanism surrounding the light source and camera that is placed on the skin of the individual when the system is in use. The ancillary apparatus thus creates a light tight seal between the skin, light source and camera, enabling the system to receive the most accurate data from the camera.

Abstract: The present invention provides a system and method for determining bilirubin levels in an individual based on skin coloration using a smartphone or other personal device and an attached ancillary apparatus. The device, such as a smartphone or tablet, is capable of storing and running software. The device is also coupled to both a camera and light source to obtain data regarding the skin's coloration. Software is installed on the device to control the light source and calculate bilirubin levels in the individual based on the input received from the camera. The ancillary apparatus is a mechanism surrounding the light source and camera that is placed on the skin of the individual when the system is in use. The ancillary apparatus thus creates a light tight seal between the skin, light source and camera, enabling the system to receive the most accurate data from the camera.