Patents by Inventor Matthew James Mitcheltree

Matthew James Mitcheltree has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Lincosamide antibiotics and uses thereof
    Patent number: 11767341
    Abstract: Provided are lincosamide compounds for the treatment of infectious diseases. The lincosamides described herein are modified at the amino acid (southern) region. The lincosamides may have further modification at the C-1 and C-7 positions of the aminooctose (northern) region, thus distinguishing them from lincomycin and clindamycin. Also provided are methods for preparing the lincosamide compounds, pharmaceutical compositions comprising the lincosamide compounds, and methods of treating infectious diseases using the disclosed lincosamide compounds.
    Type: Grant
    Filed: September 8, 2021
    Date of Patent: September 26, 2023
    Assignee: President and Fellows of Harvard College
    Inventors: Andrew G. Myers, Matthew James Mitcheltree, Katherine J. Silvestre
  • LINCOSAMIDE ANTIBIOTICS AND USES THEREOF
    Publication number: 20230203081
    Abstract: Provided are compounds of Formula (I) for the treatment of infectious and inflammatory diseases. The compounds described herein are lincosamides modified at the amino acid (southern) region. The compounds may have further modification at the C-7 position of the aminooctose (northern) region, thus distinguishing them from lincomycin and clindamycin. Also provided are methods for preparing the compounds, pharmaceutical compositions comprising the compounds, and methods of treating infectious diseases using the disclosed compounds.
    Type: Application
    Filed: May 20, 2021
    Publication date: June 29, 2023
    Applicant: President and Fellows of Harvard College
    Inventors: Andrew G. Myers, Katherine J. Silvestre, Matthew James Mitcheltree, Giambattista Testolin, Jeremy D. Mason, Aditya Pote, Daniel Terwilliger
  • Lincosamide antibiotics and uses thereof
    Patent number: 11566039
    Abstract: Provided are lincosamide compounds for the treatment of infectious diseases. The lincosamides described herein are modified at the C-7 position of the aminooctose (northern) region, thus distinguishing them from lincomycin and clindamycin. Also provided are methods for preparing the lincosamide compounds, pharmaceutical compositions comprising the lincosamide compounds, and methods of treating infectious diseases using the disclosed lincosamide compounds.
    Type: Grant
    Filed: August 10, 2018
    Date of Patent: January 31, 2023
    Assignee: President and Fellows of Harvard College
    Inventors: Andrew G. Myers, Matthew James Mitcheltree
  • LINCOSAMIDE ANTIBIOTICS AND USES THEREOF
    Publication number: 20220073554
    Abstract: Provided are lincosamide compounds for the treatment of infectious diseases. The lincosaniides described herein are modified at the amino acid (southern) region. The lincosamides may have further modification at the C-1 and C-7 positions of the aminooctose (northern) region, thus distinguishing them from lincomycin and clindamycin. Also provided are methods for preparing the lincosamide compounds, pharmaceutical compositions comprising the lincosamide compounds, and methods of treating infectious diseases using the disclosed lincosamide compounds.
    Type: Application
    Filed: September 8, 2021
    Publication date: March 10, 2022
    Applicant: President and Fellows of Harvard College
    Inventors: Andrew G. Myers, Matthew James Mitcheltree, Katherine J. Silvestre
  • Lincosamide antibiotics and uses thereof
    Patent number: 11124534
    Abstract: Provided are lincosamide compounds for the treatment of infectious diseases. The lincosamides described herein are modified at the amino acid (southern) region. The lincosamides may have further modification at the C-1 and C-7 positions of the aminooctose (northern) region, thus distinguishing them from lincomycin and clindamycin. Also provided are methods for preparing the lincosamide compounds, pharmaceutical compositions comprising the lincosamide compounds, and methods of treating infectious diseases using the disclosed lincosamide compounds.
    Type: Grant
    Filed: August 10, 2018
    Date of Patent: September 21, 2021
    Assignee: President and Fellows of Harvard College
    Inventors: Andrew G. Myers, Matthew James Mitcheltree, Katherine J. Silvestre
  • LINCOSAMIDE ANTIBIOTICS AND USES THEREOF
    Publication number: 20210087215
    Abstract: Provided are lincosamide compounds for the treatment of infectious diseases. The lincosamides described herein are modified at the C-7 position of the aminooctose (northern) region, thus distinguishing them from lincomycin and clindamycin. Also provided are methods for preparing the lincosamide compounds, pharmaceutical compositions comprising the lincosamide compounds, and methods of treating infectious diseases using the disclosed lincosamide compounds.
    Type: Application
    Filed: August 10, 2018
    Publication date: March 25, 2021
    Applicant: President and Fellows of Harvard College
    Inventors: Andrew G. Myers, Matthew James Mitcheltree
  • LINCOSAMIDE ANTIBIOTICS AND USES THEREOF
    Publication number: 20200339620
    Abstract: Provided are lincosamide compounds for the treatment of infectious diseases. The lincosamides described herein are modified at the amino acid (southern) region. The lincosamides may have further modification at the C-1 and C-7 positions of the aminooctose (northern) region, thus distinguishing them from lincomycin and clindamycin. Also provided are methods for preparing the lincosamide compounds, pharmaceutical compositions comprising the lincosamide compounds, and methods of treating infectious diseases using the disclosed lincosamide compounds.
    Type: Application
    Filed: August 10, 2018
    Publication date: October 29, 2020
    Applicant: President and Fellows of Harvard College
    Inventors: Andrew G. Myers, Matthew James Mitcheltree, Katherine J. Silvestre