Abstract: The invention relates to a composition for preparing a 3D scaffold for culturing cells and tissue, such as human cells and tissue. In particular embodiments, the present invention relates to a composition comprising a biocompatible polymer suitable for the preparation of a hydrogel, and a modified extracellular matrix (ECM) protein that is unreactive towards the biocompatible polymer, such that, after preparation of a hydrogel, the modified ECM protein is not covalently bound to the hydrogel. Compositions of the invention are suitable for use in 3D bioprinting, tissue engineering, drug screening, disease modelling and methods of treatment such as tissue regeneration.

Abstract: Provided herein are Complement Factor I (CFI) variants that exhibit at least one improved characteristic relative to a wild type CFI. CFI variants of the disclosure can exhibit tunable specificity and activity. Also included are CFI-containing fusion constructs comprising at least one domain of CFI, for example, wild type full length CFI fused to human serum albumin. Also included are methods of making and using such CFI variants and fusion constructs. The CFI variants and fusion constructs provided herein may be useful for treating a disease or condition associated with dysregulation of the complement system or a deficiency of CFI.

Abstract: A flexible optical fiber connector comprises a first housing component configured to couple to a terminating connector, and a second housing component configured to receive an optical fiber for termination in the terminating connector. The first housing component and the second housing component are further configured to receive a pushable connector therethrough. A flexible optical fiber connector assembly comprises a flexible connector and a terminating connector coupled thereto. The flexible connector assembly is configured to couple to an adapter held by a holder coupled to a port.

Abstract: Systems and methods are provided reducing storage space occupied by a media asset by adjusting quality levels of the media asset downward over time. This may be accomplished by a media guidance application that store, at a given time, the media asset in a first format having a first quality level. The media guidance application retrieves, from a database, a data entry corresponding to the media asset and determines, based on the data entry, a threshold period of time for storing the media asset in the first format. The media guidance application detects whether the threshold period of time since the given time has passed and responds by altering a first portion of the media asset from the first format having the first quality level to a second format having a second quality level that is inferior to the first quality level.

Abstract: An example method is provided for resuming a communication session encrypted using a post-quantum cipher. The example method can include receiving, by a first computing system, a resumption message from a second computing system. The example method can include decrypting, by the first computing system, the resumption message to obtain a resumption secret, wherein the resumption secret is based on at least a portion of a shared secret that was obtained using a post-quantum cipher during a prior handshake sequence between the first computing system and the second computing system. The example method can include encrypting, by the first computing system, one or more messages using a session key based on the resumption secret. The example method can include sending, by the first computing system, the encrypted one or more messages to the second computing system.

Abstract: High availability network services are provided in a communications network comprising a plurality of network devices including a network function implemented as two instances configured as an active instance and a backup instance. The backup instance maintains state data such that the backup instance can actively provide services in response to a failure of the active instance. A pool of data forwarding functions sends, over a tunnel connection, ingress data packets to the network function based on a MAC address of the active instance on an overlay network. When the active instance has failed, the backup instance provides the network function and the pool of data forwarding functions sends over the tunnel connection, subsequent ingress data packets to the network function based on an overlay network MAC address of the backup instance.

Abstract: Systems and methods are provided for obtaining, training, and using an end-to-end AST model based on a neural transducer, the end-to-end AST model comprising at least (i) an acoustic encoder which is configured to receive and encode audio data, (ii) a prediction network which is integrated in a parallel model architecture with the acoustic encoder in the end-to-end AST model, and (iii) a joint layer which is integrated in series with the acoustic encoder and prediction network. The end-to-end AST model is configured to generate a transcription in the second language of input audio data in the first language such that the acoustic encoder learns a plurality of temporal processing paths.

Abstract: A walker with an automated power drive system is disclosed. The walker comprises a rigid frame comprising a left grip and a right grip; a plurality of wheels affixed to the rigid frame; a plurality of drive motors integrally mounted in the plurality of wheels; and a drive motor controller configured to power the plurality of drive motors.

Abstract: Techniques are disclosed for migrating a computer application from an entity's premises to a web services platform. Data from multiple sources on the entity's premises is gathered and normalized into a common format. The normalized data is used to create a topology of the network on the entity's premises. This topology is analyzed to determine whether a computer application executing on the entity's premises may be migrated to the web service platform.

Abstract: Systems and methods are described for imparting dynamic, non-linear and realistic movement and look and feel to a player's/virtual character's first-person limbs and hand-held object model, and procedurally animating a first-person virtual camera such that it simulates the movement of a camera handheld by the player/virtual character. To impart chaotic or random motion to the first-person limbs and hand-held object model a first module defines and implements first and second two dimensional mass-spring-damper systems, each of which is linked to the player's/virtual vector's view vector. Procedural animation or rotational shake is implemented by a second module by applying a coherent noise function to each of the six axes of the first-person virtual camera.

Abstract: A device attaches an animal carrier to a bicycle. The device includes an adjustable arm having a first end and a second end. The adjustable arm includes a bicycle coupling at the first end, for securing the arm to the bicycle. The adjustable arm further includes a carrier mount at the second end, for mounting the animal carrier to the arm. The arm is adjustable such that the carrier mount is rotatable relative to the bicycle coupling.

Abstract: Adjustable tissue repair systems and methods are provided for reducing and fixating tissue to bone. The proposed systems and methods utilize two or more suture anchors and one or more adjustable suture loops for reducing and fixating the tissue to the bone. The suture anchors may be positioned as part of a multi-row fixation technique for providing a desired area of footprint compression over top of the tissue.

Abstract: Disclosed are new and improved instruments, systems, and methods that relate to the field of orthopedic surgical instruments.

Abstract: Provided is a probe system for low-temperature high-precision heat transport measurement, the probe system including a sample loader where a sample is loaded. In the probe system for low-temperature high-precision heat transport measurement, the sample loader includes a first frame including a sample loading space, and a second frame including an open end coupled to the first frame to accommodate the sample loading space.

Abstract: Automated provisioning, according to one example embodiment, enables a mutual customer to establish an intelligent and automated connection between an accounting software system and their financial institution. For example, this might be achieved by allowing a financial institution customer to make feeds from their bank accounts available to the accounting software system within financial internet software (e.g., hosted and operated by the customer's financial institution). Once a customer selects the bank account(s) they want to share with the accounting software system, they are passed along to the accounting software system to link the selected bank account with an account they have set up in the accounting software system.

Abstract: An ion exchangeable glass having a high degree of resistance to damage caused by abrasion, scratching, indentation, and the like. The glass comprises alumina, B2O3, and alkali metal oxides, and contains boron cations having three-fold coordination. The glass, when ion exchanged, has a Vickers crack initiation threshold of at least 10 kilogram force (kgf).

Abstract: Methods and systems for providing a network protocol for view replication over an unreliable network are described herein. A sender and a receiver may apply a branching time model to the history of views to replicate the views consistently. The sender may send a first data packet to receiver. The first data packet may comprise a first sequence number identifying the first data packet, a source version number, and a first set of one or more changes to be applied to a first state identified by the source version number. Based on a determination that an acknowledgment message indicating receipt of the first data packet is not received, the sender may send a second data packet to the client device. The content of the second data packet may be determined based on the first data packet.

Abstract: Disclosed are embodiments for facilitating a backup system for observability, communication, and control of autonomous systems. In some aspects, an embodiment includes initializing an instance of a backup tool to provide observability, communication, and control of a fleet of autonomous vehicles (AVs) responsive to an outage of primary fleet tool services; storing AV data received from the fleet of AVs in in-memory storage of the instance of the backup tool; populating a cache of the backup tool with semi-static data corresponding to the fleet of AVs; authenticating a user requesting access to the instance, the authenticating to utilize credentials of the user established with the primary fleet tool services; and facilitating the issuance of one or more control commands to the fleet of AVs based on the AV data stored in the in-memory storage and based on the semi-static data stored in the cache.

Abstract: A glass manufacturing apparatus includes a forming apparatus defining a travel path extending in a travel direction. The forming apparatus conveys a ribbon of glass-forming material along the travel path in the travel direction of the forming apparatus. The glass manufacturing apparatus includes a cooling tube extending substantially parallel to the travel path and extending across the travel direction. The cooling tube includes a plurality of orifices spaced apart along the cooling tube and facing the travel path. Methods of manufacturing glass can comprise flowing a coolant from an outlet of a conduit in a direction toward a target location of a flowing ribbon of molten material. Methods can also include changing a phase of the coolant while the coolant is flowing towards the target location. The change in phase can cool the target location.