Patents by Inventor Matthew Kostura

Matthew Kostura has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS OF TREATMENT OF CANCER WITH SUBSTITUTED PYRROLE AND PYRAZOLE COMPOUNDS AND DIAGNOSIS OF CANCERS SUSCEPTIBLE TO TREATMENT WITH SUBSTITUTED PYRROLE AND PYRAZOLE COMPOUNDS
    Publication number: 20210278408
    Abstract: Provided are methods of treatment of cancer with substituted pyrrole and pyrazole compounds and diagnoses of cancers susceptible to treatment with substituted pyrrole and pyrazole compounds, based on certain biomarkers identified herein.
    Type: Application
    Filed: June 7, 2019
    Publication date: September 9, 2021
    Inventors: Matthew Kostura, Michael Luther
  • Tricyclic Compounds as Modulators of TNF-alpha Synthesis and as PDE4 Inhibitors
    Publication number: 20110160234
    Abstract: The present invention relates to chemical compounds of Formula (I) are as herein defined, pharmaceutical compositions, and methods of use in the treatment of conditions or disorders mediated by TNF-? or by PDE4, including but not limited to rheumatoid arthritis.
    Type: Application
    Filed: March 4, 2011
    Publication date: June 30, 2011
    Applicant: HIGH POINT PHARMACEUTICALS, LLC
    Inventors: Adnan M.M. Mjalli, Bapu Gaddam, Dharma Rao Polisetti, Matthew Kostura, Mustafa Guzel
  • Tricyclic compounds as modulators of TNF-? synthesis
    Patent number: 7964608
    Abstract: The present invention relates to chemical compounds of Formula (I) are as herein defined, pharmaceutical compositions, and methods of use in the treatment of conditions or disorders mediated by TNF-alpha or by PDE4, including but not limited to rheumatoid arthritis.
    Type: Grant
    Filed: January 23, 2009
    Date of Patent: June 21, 2011
    Assignee: High Point Pharmaceuticals, LLC
    Inventors: Adnan M. M. Mjalli, Bapu Gaddam, Dharma Rao Polisetti, Matthew Kostura, Mustafa Guzel
  • Tricyclic Compounds As Modulators of TNF-alpha Synthesis
    Publication number: 20100190808
    Abstract: The present invention relates to chemical compounds of Formula (I) are as herein defined, pharmaceutical compositions, and methods of use in the treatment of conditions or disorders mediated by TNF-alpha or by PDE4, including but not limited to rheumatoid arthritis.
    Type: Application
    Filed: January 23, 2009
    Publication date: July 29, 2010
    Applicant: HIGH POINT PHARMACEUTICALS, LLC.
    Inventors: Adnan M. M. Mjalli, Bapu Gaddam, Dharmo Rao, Matthew Kostura, Mustafa Guzel