Patents by Inventor Matthew L. Charles

Matthew L. Charles has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR TREATING DIABETES
    Publication number: 20140134152
    Abstract: Embodiments of the present invention relate to compositions and methods of treating patients for type 1 diabetes mellitus (T1D) by administering a therapeutically effective dose of recombinant human KLK1, variants of KLK1, or active fragments thereof. Such patients may be increase risk patients for developing T1D or T1D patients in the Honeymoon Phase. Such treatment may be expected to prevent or delay the onset of T1D, to ameliorate the symptoms of T1D, or to ameliorate the extent to which the T1D manifests.
    Type: Application
    Filed: May 4, 2012
    Publication date: May 15, 2014
    Applicant: DiaMedica Inc.
    Inventors: Mark S Willimas, Matthew L. Charles
  • ANTI-BRADYKININ B2 RECEPTOR (BKB2R) MONOCLONAL ANTIBODY
    Publication number: 20140017242
    Abstract: The present invention relates generally to anti-bradykinin B2 receptor (BKB2R) antibodies and methods for making and using them. In particular, the anti-BKB2R antibodies having the variable region sequences described herein are useful for altering one or more of BKB2R of and/or GSK-3 signaling pathways for the treatment of diseases, disorders and conditions such as cancer, diabetes, cardiovascular disorders and other conditions.
    Type: Application
    Filed: December 1, 2011
    Publication date: January 16, 2014
    Applicant: DIAMEDICA INC.
    Inventors: Mark S. Williams, Matthew L. Charles
  • TISSUE KALLIKREIN FOR THE TREATMENT OF PARKINSON'S DISEASE
    Publication number: 20120276019
    Abstract: Provided herein are methods of treating Parkinson's disease, dementia with Lewy bodies, and conditions associated with Parkinson's disease and dementia with Lewy bodies. These methods include administering to a subject in need thereof a therapeutically effective amount of a tissue kallikrein (KLK1) polypeptide, including active variants and fragments thereof.
    Type: Application
    Filed: June 12, 2012
    Publication date: November 1, 2012
    Applicant: DIAMEDICA INC.
    Inventors: Matthew L. Charles, Mark S. Williams
  • TISSUE KALLIKREIN FOR THE TREATMENT OF PARKINSON'S DISEASE
    Publication number: 20110150781
    Abstract: The invention relates to methods of treating Parkinson's disease, dementia with Lewy bodies, and conditions associated with Parkinson's disease and dementia with Lewy bodies. Methods include administering a therapeutically effective amount of tissue kallikrein, variants or active fragments thereof.
    Type: Application
    Filed: July 24, 2009
    Publication date: June 23, 2011
    Applicant: DiaMedica Inc.
    Inventors: Matthew L. Charles, Mark Williams