Patents by Inventor Matthew Lakins

Matthew Lakins has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • FC BINDING FRAGMENTS COMPRISING A CD137 ANTIGEN-BINDING SITE
    Publication number: 20220119539
    Abstract: The invention relates to specific binding members that bind CD137. The specific binding members comprise a CD137 antigen-binding site located in a constant domain of the specific binding member and find application in the treatment of cancer and infectious diseases, for example.
    Type: Application
    Filed: July 12, 2019
    Publication date: April 21, 2022
    Applicant: F-star Beta Limited
    Inventors: Matthew Lakins, Jose Munoz-Olaya, Sarka Pechouckova, Mihriban Tuna
  • ANTIBODY MOLECULES THAT BIND PD-L1 AND CD137
    Publication number: 20220049007
    Abstract: The present application relates to antibody molecules that bind both PD-L1 and CD 137 and are able to induce agonism of CD137. The antibody molecules comprise a CDR-based binding site for PD-L1, and a CD137 antigen-binding site that is located in a constant domain of the antibody molecule. The antibody molecules of the invention find application, for example, in the treatment of diseases, such as cancer.
    Type: Application
    Filed: July 12, 2019
    Publication date: February 17, 2022
    Applicant: F-star Beta Limited
    Inventors: Matthew Lakins, Jose Munoz-Olaya, Francisca Wollerton, Sarah Batey, Mihriban Tuna, Alexander Koers
  • ANTIBODY MOLECULES
    Publication number: 20210301022
    Abstract: An antibody molecule, or antigen-binding fragment thereof capable of binding specifically to PD-L1.
    Type: Application
    Filed: July 12, 2019
    Publication date: September 30, 2021
    Applicant: F-Star Beta Limited
    Inventors: Francisca Wollerton, Matthew Lakins, Mateusz Wydro, Sachin Surade, Michael Dyson
  • FC BINDING FRAGMENTS COMPRISING A CD137 ANTIGEN-BINDING SITE
    Publication number: 20210277134
    Abstract: The invention relates to specific binding members that bind CD137. The specific binding members comprise a CD137 antigen-binding site located in a constant domain of the specific binding member and find application in the treatment of cancer and infectious diseases, for example.
    Type: Application
    Filed: July 12, 2019
    Publication date: September 9, 2021
    Applicant: F-star Beta Limited
    Inventors: Matthew Lakins, Jose Munoz-Olaya, Sarka Pechouckova, Mihriban Tuna