Patents by Inventor Matthew LaPorte

Matthew LaPorte has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • IAP INHIBITORS
    Publication number: 20080021066
    Abstract: Smac mimetics that inhibit IAPs.
    Type: Application
    Filed: July 24, 2007
    Publication date: January 24, 2008
    Inventors: Stephen Condon, Matthew LaPorte, Yijun Deng, Susan Rippin
  • DIMERIC IAP INHIBITORS
    Publication number: 20080020986
    Abstract: Smac mimetics that inhibit IAPs.
    Type: Application
    Filed: July 24, 2007
    Publication date: January 24, 2008
    Inventors: Stephen Condon, Matthew LaPorte, Yijun Deng, Susan Rippin
  • Pyranouidole Derivatives and the Use Thereof for the Treatment of Hepatitis C Virus Infection or Disease
    Publication number: 20070219212
    Abstract: The invention is directed to novel pyranoindole derivatives and analogs as well as compositions containing the same and to the use thereof for the treatment, prevention or inhibition of viral infections and associated diseases caused by the Hepatitis C virus.
    Type: Application
    Filed: March 1, 2005
    Publication date: September 20, 2007
    Inventors: Stephen Condon, Randy Jackson, Matthew Laporte, Christopher Burns, Torsten Herbertz, Janet Gaboury
  • Dimeric IAP inhibitors
    Publication number: 20060194741
    Abstract: Molecular mimics of Smac are capable of modulating apoptosis through their interaction with cellular IAPs (inhibitor of apoptosis proteins). The mimetics are based on a monomer or dimer of the N-terminal tetrapeptide of IAP-binding proteins, such as Smac/DIABLO, Hid, Grim and Reaper, which interact with a specific surface groove of LAP. Also disclosed are methods of using these peptidomimetics for therapeutic purposes.
    Type: Application
    Filed: February 27, 2006
    Publication date: August 31, 2006
    Inventors: Stephen Condon, Matthew LaPorte, Yijun Deng, Susan Rippin
  • IAP binding compounds
    Publication number: 20060025347
    Abstract: IAP binding molecules and compositions including these are disclosed. The IAP binding molecules interact with IAPs (inhibitor of apoptosis proteins) in cells and may be used to modify apoptosis in cells treated with such molecules. Embodiments of these compounds have a Kd of less that 0.1 micromolar. Methods of using these IAP binding molecules for therapeutic, diagnostic, and assay purposes are also disclosed.
    Type: Application
    Filed: July 15, 2005
    Publication date: February 2, 2006
    Inventors: Stephen Condon, Matthew LaPorte, Yijun Deng, Susan Rippin