Abstract: A method for generating a graphical representation of a customer-service interaction includes storing a library of predefined graphical elements and information defining a plurality of placement zones for use in image compositing. The method also includes receiving one or more custom graphical elements that are associated with a specified employer and selections that identify a group of selected graphical elements. The group of selected graphical elements includes one or more of the predefined graphical elements and one or more of the custom graphical elements. Each graphical element from the group of graphical elements is associated with a respective placement zone from the plurality of placement zones. A composite image including each selected graphical element is generated with the graphical elements positioned according to respective placement zones. The composite image can be stored at the server and output for display.

Abstract: The present invention involves tetrahydroisoquinoline compounds and their use in the inhibition and/or prevention of tumor growth.

Abstract: A computer-implemented method for publishing a user credential includes receiving a score regarding at least one capability of an individual, wherein the score is based at least on a plurality of test inputs provided by the individual in response to an assessment test; receiving permission, from the individual, to allow publication of a credential certificate on a computer-implemented user profile associated with the individual, wherein the credential certificate is based at least in part on the score and includes at least one interface element for requesting additional information related to the individual; publishing the credential certificate and at least one interface element on the computer-implemented user profile associated with the individual; and providing a link to the additional information in response to a request for the additional information from the authorized employer, wherein the request is based on activation of at least one interface element by the authorized employer.

Abstract: A competency assessment method for evaluating at least one capability on of an individual seeking or holding a job with a specified employer includes assessing a plurality of competencies to determine the degree to which each competency is able to predict whether the individual possesses the capability without regard to the nature or industry of the job with the specified employer; selecting a subset of the competencies based on ability of each competency to predict whether the individual possesses the capability; accepting as input at least one user-generated assessment that is relevant to each competency of the subset of competencies; and generating as output a score indicative of the individual's capability based on the at least one user-generated assessment.

Abstract: The present invention provides a compound comprising a steroidal ring system and an optional group R1 selected from any one of —OH, a sulphamate group, a phosphonate group, a thiophosphonate group, a sulphonate group or a sulphonamide group; wherein the D ring of the steroidal ring system is substituted by a group R2 of the formula -L-R3, wherein L is an optional linker group and R3 is selected from groups which are or which comprise one of a nitrite group, an alcohol, an ester, an ether, an amine and an alkene, provided that when R3 is or comprises an alcohol, L is present; and wherein the A ring of the steroidal ring system is substituted at position 2 or 4 with a group R4, wherein R4 is a hydrocarbyl group.

Abstract: The present invention involves tetrahydroisoquinoline compounds and their use in the inhibition and/or prevention of tumor growth.

Abstract: The present invention provides a compound comprising a steroidal ring system and an optional group R1 selected from any one of —OH, a sulphamate group, a phosphonate group, a thiophosphonate group, a sulphonate group or a sulphonamide group; wherein the A ring of the steroidal ring system is optionally substituted at position 2 or 4 with a group R4 which may be a suitable subtituent, wherein the D ring of the steroidal ring system is substituted by a group R2 of the formula -L-R3, wherein L is an optional linker group and R3 is selected from groups which are or which comprise one of (i) —SO2R5, wherein R5 is H, a hydrocarbyl group or a bond or group attached to the D ring; (ii) —NO2; (iii) —SOR6, wherein R6 is H or a hydrocarbyl group; (iv) —R7, wherein R7 is a halogen; (v) -alkyl; (vi) —C(?O)R3, wherein R3 is H or hydrocarbyl; (vii) —C?CR9, wherein R9 is H or hydrocarbyl; (viii) —OC(?O)NR10R11 wherein R10 and R11 are independently selected from H and hydrocarbyl; (ix), (x), (xi), (xii) and (xiii) are formula

Abstract: There is provided a compound of Formula I wherein X is a ring system; R1 is any one of a sulphamate group, a phosphonate group, a thiophosphonate group, a sulphonate group or a sulphonamide group; R2 is any one of a sulphamate group, a phosphonate group, a thiophosphonate group, a sulphonate group or a sulphonamide group; wherein when X is a steroidal structure and both of R1 and R2 are sulphamate groups, the steroidal ring system (X) represents an oestrogen; and wherein said compound is capable of inhibiting steroid sulphatase (STS) activity and/or is capable of acting as a modulator of cell cycling and/or as a modulator of apoptosis and/or as a modulator of cell growth.