Patents by Inventor Matthew M. Hayward

Matthew M. Hayward has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Sulfonyl amide derivatives for the treatment of abnormal cell growth
    Patent number: 10450297
    Abstract: The present invention relates to a compound of the formula I wherein R1 to R6, A, B, n and m are as defined herein. Such novel sulfonyl amide derivatives are useful in the treatment of abnormal cell growth, such as cancer, in mammals. This invention also relates to a method of using such compounds in the treatment of abnormal cell growth in mammals, especially humans, and to pharmaceutical compositions containing such compounds.
    Type: Grant
    Filed: April 5, 2018
    Date of Patent: October 22, 2019
    Assignee: Pfizer, Inc.
    Inventors: Michael J. Luzzio, Kevin D. Freeman-Cook, Samit K. Bhattacharya, Matthew M. Hayward, Catherine A. Hulford, Christopher L. Autry, Xumiao Zhao, Jun Xiao, Kendra L. Nelson
  • SULFONYL AMIDE DERIVATIVES FOR THE TREATMENT OF ABNORMAL CELL GROWTH
    Publication number: 20190047979
    Abstract: The present invention relates to a compound of the formula I wherein R1 to R6, A, B, n and m are as defined herein. Such novel sulfonyl amide derivatives are useful in the treatment of abnormal cell growth, such as cancer, in mammals. This invention also relates to a method of using such compounds in the treatment of abnormal cell growth in mammals, especially humans, and to pharmaceutical compositions containing such compounds.
    Type: Application
    Filed: April 5, 2018
    Publication date: February 14, 2019
    Inventors: Michael J. Luzzio, Kevin D. Freeman-Cook, Samit K. Bhattacharya, Matthew M. Hayward, Catherine A. Hulford, Christopher L. Autry, Xumiao Zhao, Jun Xiao, Kendra L. Nelson
  • SULFONYL AMIDE DERIVATIVES FOR THE TREATMENT OF ABNORMAL CELL GROWTH
    Publication number: 20170327485
    Abstract: The present invention relates to a compound of the formula I wherein R1 to R6, A, B, n and m are as defined herein. Such novel sulfonyl amide derivatives are useful in the treatment of abnormal cell growth, such as cancer, in mammals. This invention also relates to a method of using such compounds in the treatment of abnormal cell growth in mammals, especially humans, and to pharmaceutical compositions containing such compounds.
    Type: Application
    Filed: April 20, 2017
    Publication date: November 16, 2017
    Inventors: Michael J. Luzzio, Kevin D. Freeman-Cook, Samit K. Bhattacharya, Matthew M. Hayward, Catherine A. Hulford, Christopher L. Autry, Xumiao Zhao, Jun Xiao, Kendra L. Nelson
  • Bicyclic and tricyclic compounds as KAT II inhibitors
    Patent number: 8183238
    Abstract: Compounds of Formula X: wherein A, X, Y, Z, R5, R6a, and R6b are as defined herein, and pharmaceutically acceptable salts thereof, are described as useful for the treatment of cognitive deficits associated with schizophrenia and other neurodegenerative and/or neurological disorders in mammals, including humans.
    Type: Grant
    Filed: June 16, 2010
    Date of Patent: May 22, 2012
    Assignee: Pfizer Inc.
    Inventors: Michelle M. Claffey, Amy B. Dounay, Matthew M. Hayward, Suobao Rong, Patrick R. Verhoest, Jamison B. Tuttle, Xinmin Gan
  • Bicyclic And Tricyclic Compounds As KAT II Inhibitors
    Publication number: 20100324043
    Abstract: Compounds of Formula X: wherein A, X, Y, Z, R5, R6a, and R6b are as defined herein, and pharmaceutically acceptable salts thereof, are described as useful for the treatment of cognitive deficits associated with schizophrenia and other neurodegenerative and/or neurological disorders in mammals, including humans.
    Type: Application
    Filed: June 16, 2010
    Publication date: December 23, 2010
    Inventors: Michelle M. Claffey, Amy B. Dounay, Matthew M. Hayward, Suobao Rong, Patrick R. Verhoest, Jamison B. Tuttle, Xinmin Gan
  • Piperazine derivatives
    Patent number: 7098212
    Abstract: The present invention relates to compounds of the formula I and the pharmaceutically acceptable forms thereof; wherein X, Y, a, b, c, d, R1, R2, R3, R4 and R5 are as defined herein. Moreover, the present invention is also directed at pharmaceutical compositions comprising a compound of the formula I and a pharmaceutically acceptable carrier. Furthermore, the present invention is directed at methods of using the herein described compounds and compositions for treating or preventing a disorder or condition that can be treated or prevented by antagonizing the CCR1 receptor in a mammal.
    Type: Grant
    Filed: October 18, 2002
    Date of Patent: August 29, 2006
    Inventors: Laura C. Blumberg, Matthew F. Brown, Matthew M. Hayward, Gregory D. Lundquist, Christopher S. Poss, Andrei Shavnya
  • Sulfonic acid derivatives
    Patent number: 6974817
    Abstract: A compound of the formula or the pharmaceutically acceptable salt thereof; wherein X, Y, a, b, c, d, R1, R2, R3 and R5 are as defined above useful to treat inflammation and other immune disorders.
    Type: Grant
    Filed: June 19, 2002
    Date of Patent: December 13, 2005
    Assignee: Pfizer Inc.
    Inventor: Matthew M. Hayward
  • Novel phosphorus-containing derivatives
    Publication number: 20040127465
    Abstract: A compound of the Formula I 1
    Type: Application
    Filed: December 12, 2003
    Publication date: July 1, 2004
    Applicant: Pfizer Inc
    Inventors: Matthew F. Brown, Matthew M. Hayward
  • Methods of using sulfonic acid derivatives
    Publication number: 20040116441
    Abstract: The present invention relates to methods of using CCR1 antagonists as immunomodulatory agents.
    Type: Application
    Filed: October 16, 2003
    Publication date: June 17, 2004
    Applicant: Pfizer Inc
    Inventors: Matthew F. Brown, Anderson S. Gaweco, Ronald P. Gladue, Matthew M. Hayward
  • Methods of using piperazine derivatives
    Publication number: 20040092529
    Abstract: The present invention relates to compounds of the formula I 1
    Type: Application
    Filed: October 16, 2003
    Publication date: May 13, 2004
    Applicant: Pfizer Inc
    Inventors: Laura C. Blumberg, Matthew F. Brown, Anderson S. Gaweco, Ronald P. Gladue, Matthew M. Hayward, Gregory D. Lundquist, Christopher S. Poss, Andrei Shavnya
  • Novel piperidine derivatives
    Publication number: 20040063688
    Abstract: A compound of the formula 1
    Type: Application
    Filed: July 8, 2003
    Publication date: April 1, 2004
    Applicant: Pfizer Inc.
    Inventors: Laura C. Blumberg, Matthew F. Brown, Matthew M. Hayward, Christopher S. Poss
  • Novel piperidine derivatives
    Publication number: 20040063759
    Abstract: A compound of the formula 1
    Type: Application
    Filed: July 8, 2003
    Publication date: April 1, 2004
    Applicant: Pfizer Inc.
    Inventors: Laura C. Blumberg, Matthew F. Brown, Matthew M. Hayward, Christopher S. Poss
  • Novel piperazine derivatives
    Publication number: 20040034034
    Abstract: The present invention relates to compounds of the formula I 1
    Type: Application
    Filed: October 18, 2002
    Publication date: February 19, 2004
    Inventors: Laura C. Blumberg, Matthew F. Brown, Matthew M. Hayward, Gregory D. Lundquist, Christopher S. Poss, Andrei Shavnya
  • Hygromycin derivatives
    Patent number: 6562792
    Abstract: The present invention relates to compounds of the formula 1 and to pharmaceutically acceptable salts, prodrugs and solvates thereof, wherein X, Y, V, W1, W2, Z1 and Z2 are as defined herein. The invention also relates to pharmaceutical compositions containing the above compounds and to methods of treating bacterial and protozoal infections in mammals by administering the above compounds.
    Type: Grant
    Filed: October 20, 2000
    Date of Patent: May 13, 2003
    Assignee: Pfizer Inc.
    Inventors: Katherine E. Brighty, Robert G. Linde, Takushi Kaneko, Matthew M. Hayward
  • Novel sulfonic acid derivatives
    Publication number: 20030083335
    Abstract: A compound of the formula 1
    Type: Application
    Filed: June 19, 2002
    Publication date: May 1, 2003
    Inventor: Matthew M. Hayward