Abstract: Stents and/or endoluminal implants for extending across two non-adherent structures/tissues. An illustrative stent may comprise an elongated tubular body having a scaffolding forming a plurality of cells and a coating disposed over an outer surface of the elongated tubular body. The coating may comprise a first micro-porous layer and a macro-porous layer including a plurality of loops disposed over the micro-porous layer.

Abstract: An apposition device having a first elongate element movably coupled with a second elongate element. The second elongate element is deployable distal to the structures to be apposed, in a position transverse to the first elongate element. The first elongate element may be pulled to pull the second elongate element to move the structures into apposition. A third element may be positioned proximal to the structures to hold the structures in apposition. The third element may be a ratcheting element fixable in place with respect to the first elongate element. The apposition device may be deployed with a fine gauge needle. The second elongate element may be deployed from a side port in the needle facilitating deployment, and/or movement of the second elongate element with respect to the first elongate element and into a deployment configuration. Such arrangement may allow control of the first elongate element independent of the needle.

Abstract: A flexible elongate member with the ability to deliver a material through a medium-delivery channel defined within a wall thereof. The flexible elongate member may have a tubular wall defining a lumen therethrough, the medium-delivery channel being formed within the tubular wall. The flexible elongate member may be a reinforced flexible tubular elongate member with a reinforcing layer within the tubular wall thereof. One or more filaments forming the reinforcing layer may be hollow to define the medium-delivery channel extending through the reinforced flexible tubular elongate member.

Abstract: A steerable device and system allowing a steerable elongate member positioned within another steerable tubular elongate member to be steered independently of the steerable tubular elongate member. The steerable tubular elongate member may be steered in a first plane, bending the steerable elongate member therein in the first plane as well. A steering mechanism operatively associated with the steerable elongate member has a distal portion operatively associated with a steerable region of the steerable elongate member to steer such steerable region within a second plane transverse to the first plane. The steering mechanism is independently movable with respect to a portion of the steerable elongate member proximal to the steerable region so as not to affect the orientation of the steerable region to be steered into a second plane transverse to the first plane.

Abstract: An elongate medical device is adapted to provide adjustable flexibility. The elongate medical device includes an inner coil having one or more inner coil filars extending in a first direction, and an outer coil having one or more outer filars extending in a second direction. A hypotube extends proximally from the inner coil and the outer coil. A cable extends through the inner coil and through the hypotube, where a distal end of the cable, a distal end of the inner coil and a distal end of the outer coil are all secured together at a distal end of the elongate medical device, such that applying a tensile force to the cable, relative to the hypotube, causes the inner coil and outer coil in combination to increase in stiffness.

Abstract: A medical device, comprising a shaft, wherein the shaft has a corrugated body, and wherein the corrugated body includes a plurality of hoops extending around a circumference of the shaft, a plurality of indentations, wherein the plurality of indentations extend around a portion of the circumference of the shaft and define a reduced-diameter portion of the shaft relative to a diameter of the plurality of hoops, and wherein each of the plurality of hoops is spaced apart from an adjacent hoop of the plurality of hoops by at least one of the plurality of indentations, and a plurality of nodes, wherein each node extends between and connects adjacent hoops of the plurality of hoops, and wherein each of the plurality of nodes is radially offset relative to adjacent nodes along a longitudinal axis of the shaft.

Abstract: A steerable catheter includes a catheter shaft having a lumen defined by a catheter wall, a proximal portion, a distal portion, and a length extending therebetween, and at least one pullwire extending along the length of the catheter shaft and coupled to the catheter wall. The at least one pullwire has a proximal section extending along the proximal portion of the catheter shaft in a first radial position, a distal section extending along the distal portion of the catheter shaft in a second radial position, and a transition zone connecting the proximal section and the distal section. The second radial position is offset circumferentially from the first radial position.