Patents by Inventor Matthew Mancuso
Matthew Mancuso has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9821314Abstract: Disclosed are methods and apparatus for solar-thermal microfluidic polymerase chain reaction. A device comprises a microfluidic chip including at least one PCR region, an energy absorption layer disposed adjacent to the microfluidic chip, a solar energy concentrator adapted to produce a plurality of temperature profiles on the microfluidic chip adapted to facilitate PCR, and a photomask disposed between the solar energy concentrator and the microfluidic chip.Type: GrantFiled: September 18, 2013Date of Patent: November 21, 2017Assignee: CORNELL UNIVERSITYInventors: David Erickson, Li Jiang, Matthew Mancuso
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Patent number: 9787815Abstract: A method for obtaining a point-of-collection, selected quantitative indicia of an analyte on a test strip using a smartphone involves imaging a test strip on which a colorimetric reaction of a target sample has occurred due to test strip illumination by the smartphone. The smartphone includes a smartphone app and a smartphone accessory that provides an external environment-independent/internal light-free, imaging environment independent of the smartphone platform being used. The result can then be presented quantitatively or turned into a more consumer-friendly measurement (positive, negative, above average, etc.), displayed to the user, stored for later use, and communicated to a location where practitioners can provide additional review. Additionally, social media integration can allow for device results to be broadcast to specific audiences, to compare healthy living with others, to compete in health based games, create mappings, and other applications.Type: GrantFiled: July 21, 2015Date of Patent: October 10, 2017Assignee: CORNELL UNIVERSITYInventors: David Erickson, Seoho Lee, Dakota O'Dell, Saurabh Mehta, Vlad-Victor Oncescu, Matthew Mancuso
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Patent number: 9686395Abstract: A system, methods, and apparatus for biomolecular measurements, monitoring, and tracking uses a smartphone-based system. A biological sample, including, but not limited to blood, saliva, biopsy, or sweat, is collected on a modular diagnostic test platform, which is then inserted into a smartphone accessory. Optical, electrical, mechanical, or other means are used to transduce a biomolecular binding event, including antibody, aptamer, enzymatic, base-pair matching, or other biological recognition reaction and communicate the results with the smartphone. Some specific examples of targets include 25-hydroxyvitamin D, folic acid, DNA, or proteins from infectious agents, and zinc. The result can then be presented quantitatively or turned into a more consumer-friendly measurement (positive, negative, above average, etc.), displayed to the user, stored for later comparison, and communicated to a central hub location where medical professionals can provide additional review.Type: GrantFiled: September 6, 2013Date of Patent: June 20, 2017Assignee: CORNELL UNIVERSITYInventors: David Erickson, Matthew Mancuso, Seoho Lee
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Patent number: 9445749Abstract: A method for obtaining a point-of-collection, selected quantitative indicia of an analyte on a test strip using a smartphone involves imaging a test strip on which a colorimetric reaction of a target sample has occurred due to test strip illumination by the smartphone. The smartphone includes a smartphone app and a smartphone accessory that provides an external environment-independent/internal light-free, imaging environment independent of the smartphone platform being used. The result can then be presented quantitatively or turned into a more consumer-friendly measurement (positive, negative, above average, etc.), displayed to the user, stored for later use, and communicated to a location where practitioners can provide additional review. Additionally, social media integration can allow for device results to be broadcast to specific audiences, to compare healthy living with others, to compete in health based games, create mappings, and other applications.Type: GrantFiled: January 21, 2014Date of Patent: September 20, 2016Assignee: CORNELL UNIVERSITYInventors: David Erickson, Dakota O'Dell, Vlad-Victor Oncescu, Matthew Mancuso, Seoho Lee
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Publication number: 20160080548Abstract: A method for obtaining a point-of-collection, selected quantitative indicia of an analyte on a test strip using a smartphone involves imaging a test strip on which a colorimetric reaction of a target sample has occurred due to test strip illumination by the smartphone. The smartphone includes a smartphone app and a smartphone accessory that provides an external environment-independent/internal light-free, imaging environment independent of the smartphone platform being used. The result can then be presented quantitatively or turned into a more consumer-friendly measurement (positive, negative, above average, etc.), displayed to the user, stored for later use, and communicated to a location where practitioners can provide additional review. Additionally, social media integration can allow for device results to be broadcast to specific audiences, to compare healthy living with others, to compete in health based games, create mappings, and other applications.Type: ApplicationFiled: July 21, 2015Publication date: March 17, 2016Applicant: CORNELL UNIVERSITYInventors: David Erickson, Seoho Lee, Dakota O'Dell, Saurabh Mehta, Vlad-Victor Oncescu, Matthew Mancuso
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Publication number: 20150359458Abstract: A method for obtaining a point-of-collection, selected quantitative indicia of an analyte on a test strip using a smartphone involves imaging a test strip on which a colorimetric reaction of a target sample has occurred due to test strip illumination by the smartphone. The smartphone includes a smartphone app and a smartphone accessory that provides an external environment-independent/internal light-free, imaging environment independent of the smartphone platform being used. The result can then be presented quantitatively or turned into a more consumer-friendly measurement (positive, negative, above average, etc.), displayed to the user, stored for later use, and communicated to a location where practitioners can provide additional review. Additionally, social media integration can allow for device results to be broadcast to specific audiences, to compare healthy living with others, to compete in health based games, create mappings, and other applications.Type: ApplicationFiled: January 21, 2014Publication date: December 17, 2015Applicant: CORNELL UNIVERSITYInventors: David Erickson, Dakota O'Dell, Vlad-Victor Oncescu, Matthew Mancuso, Seoho Lee
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Publication number: 20150244852Abstract: A system, methods, and apparatus for biomolecular measurements, monitoring, and tracking uses a smartphone-based system. A biological sample, including, but not limited to blood, saliva, biopsy, or sweat, is collected on a modular diagnostic test platform, which is then inserted into a smartphone accessory. Optical, electrical, mechanical, or other means are used to transduce a biomolecular binding event, including antibody, aptamer, enzymatic, base-pair matching, or other biological recognition reaction and communicate the results with the smartphone. Some specific examples of targets include 25-hydroxyvitamin D, folic acid, DNA, or proteins from infectious agents, and zinc. The result can then be presented quantitatively or turned into a more consumer-friendly measurement (positive, negative, above average, etc.), displayed to the user, stored for later comparison, and communicated to a central hub location where medical professionals can provide additional review.Type: ApplicationFiled: September 6, 2013Publication date: August 27, 2015Applicant: CORNELL UNIVERSITYInventors: David Erickson, Matthew Mancuso, Seoho Lee
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Publication number: 20150238967Abstract: Disclosed are methods and apparatus for solar-thermal microfluidic polymerase chain reaction. A device comprises a microfluidic chip including at least one PCR region, an energy absorption layer disposed adjacent to the microfluidic chip, a solar energy concentrator adapted to produce a plurality of temperature profiles on the microfluidic chip adapted to facilitate PCR, and a photomask disposed between the solar energy concentrator and the microfluidic chip.Type: ApplicationFiled: September 18, 2013Publication date: August 27, 2015Applicant: CORNELL UNIVERSITYInventors: David Erickson, Li Jiang, Matthew Mancuso
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Publication number: 20150038361Abstract: Methods and systems for colorimetric detection of a target. Nucleic acid is obtained from a sample potentially containing two pathogens of interest, and is contacted with a plurality of nanoparticles. A first portion of the plurality of nanoparticles are functionalized with oligonucleotides complementary to a first region of the first target and oligonucleotides complementary to a second region of the first target, and a second portion of the plurality of nanoparticles are functionalized with oligonucleotides complementary to a first region of the second target and oligonucleotides complementary to a second region of the second target. The presence of the target nucleic acid causes a detectable colorimetric change, thereby diagnosing the presence of the pathogen.Type: ApplicationFiled: February 14, 2013Publication date: February 5, 2015Inventors: David Erickson, Matthew Mancuso, Ethel Cesarman, Li Jiang