Patents by Inventor Matthew Mancuso

Matthew Mancuso has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9821314
    Abstract: Disclosed are methods and apparatus for solar-thermal microfluidic polymerase chain reaction. A device comprises a microfluidic chip including at least one PCR region, an energy absorption layer disposed adjacent to the microfluidic chip, a solar energy concentrator adapted to produce a plurality of temperature profiles on the microfluidic chip adapted to facilitate PCR, and a photomask disposed between the solar energy concentrator and the microfluidic chip.
    Type: Grant
    Filed: September 18, 2013
    Date of Patent: November 21, 2017
    Assignee: CORNELL UNIVERSITY
    Inventors: David Erickson, Li Jiang, Matthew Mancuso
  • Patent number: 9787815
    Abstract: A method for obtaining a point-of-collection, selected quantitative indicia of an analyte on a test strip using a smartphone involves imaging a test strip on which a colorimetric reaction of a target sample has occurred due to test strip illumination by the smartphone. The smartphone includes a smartphone app and a smartphone accessory that provides an external environment-independent/internal light-free, imaging environment independent of the smartphone platform being used. The result can then be presented quantitatively or turned into a more consumer-friendly measurement (positive, negative, above average, etc.), displayed to the user, stored for later use, and communicated to a location where practitioners can provide additional review. Additionally, social media integration can allow for device results to be broadcast to specific audiences, to compare healthy living with others, to compete in health based games, create mappings, and other applications.
    Type: Grant
    Filed: July 21, 2015
    Date of Patent: October 10, 2017
    Assignee: CORNELL UNIVERSITY
    Inventors: David Erickson, Seoho Lee, Dakota O'Dell, Saurabh Mehta, Vlad-Victor Oncescu, Matthew Mancuso
  • Patent number: 9686395
    Abstract: A system, methods, and apparatus for biomolecular measurements, monitoring, and tracking uses a smartphone-based system. A biological sample, including, but not limited to blood, saliva, biopsy, or sweat, is collected on a modular diagnostic test platform, which is then inserted into a smartphone accessory. Optical, electrical, mechanical, or other means are used to transduce a biomolecular binding event, including antibody, aptamer, enzymatic, base-pair matching, or other biological recognition reaction and communicate the results with the smartphone. Some specific examples of targets include 25-hydroxyvitamin D, folic acid, DNA, or proteins from infectious agents, and zinc. The result can then be presented quantitatively or turned into a more consumer-friendly measurement (positive, negative, above average, etc.), displayed to the user, stored for later comparison, and communicated to a central hub location where medical professionals can provide additional review.
    Type: Grant
    Filed: September 6, 2013
    Date of Patent: June 20, 2017
    Assignee: CORNELL UNIVERSITY
    Inventors: David Erickson, Matthew Mancuso, Seoho Lee
  • Patent number: 9445749
    Abstract: A method for obtaining a point-of-collection, selected quantitative indicia of an analyte on a test strip using a smartphone involves imaging a test strip on which a colorimetric reaction of a target sample has occurred due to test strip illumination by the smartphone. The smartphone includes a smartphone app and a smartphone accessory that provides an external environment-independent/internal light-free, imaging environment independent of the smartphone platform being used. The result can then be presented quantitatively or turned into a more consumer-friendly measurement (positive, negative, above average, etc.), displayed to the user, stored for later use, and communicated to a location where practitioners can provide additional review. Additionally, social media integration can allow for device results to be broadcast to specific audiences, to compare healthy living with others, to compete in health based games, create mappings, and other applications.
    Type: Grant
    Filed: January 21, 2014
    Date of Patent: September 20, 2016
    Assignee: CORNELL UNIVERSITY
    Inventors: David Erickson, Dakota O'Dell, Vlad-Victor Oncescu, Matthew Mancuso, Seoho Lee
  • Publication number: 20160080548
    Abstract: A method for obtaining a point-of-collection, selected quantitative indicia of an analyte on a test strip using a smartphone involves imaging a test strip on which a colorimetric reaction of a target sample has occurred due to test strip illumination by the smartphone. The smartphone includes a smartphone app and a smartphone accessory that provides an external environment-independent/internal light-free, imaging environment independent of the smartphone platform being used. The result can then be presented quantitatively or turned into a more consumer-friendly measurement (positive, negative, above average, etc.), displayed to the user, stored for later use, and communicated to a location where practitioners can provide additional review. Additionally, social media integration can allow for device results to be broadcast to specific audiences, to compare healthy living with others, to compete in health based games, create mappings, and other applications.
    Type: Application
    Filed: July 21, 2015
    Publication date: March 17, 2016
    Applicant: CORNELL UNIVERSITY
    Inventors: David Erickson, Seoho Lee, Dakota O'Dell, Saurabh Mehta, Vlad-Victor Oncescu, Matthew Mancuso
  • Publication number: 20150359458
    Abstract: A method for obtaining a point-of-collection, selected quantitative indicia of an analyte on a test strip using a smartphone involves imaging a test strip on which a colorimetric reaction of a target sample has occurred due to test strip illumination by the smartphone. The smartphone includes a smartphone app and a smartphone accessory that provides an external environment-independent/internal light-free, imaging environment independent of the smartphone platform being used. The result can then be presented quantitatively or turned into a more consumer-friendly measurement (positive, negative, above average, etc.), displayed to the user, stored for later use, and communicated to a location where practitioners can provide additional review. Additionally, social media integration can allow for device results to be broadcast to specific audiences, to compare healthy living with others, to compete in health based games, create mappings, and other applications.
    Type: Application
    Filed: January 21, 2014
    Publication date: December 17, 2015
    Applicant: CORNELL UNIVERSITY
    Inventors: David Erickson, Dakota O'Dell, Vlad-Victor Oncescu, Matthew Mancuso, Seoho Lee
  • Publication number: 20150244852
    Abstract: A system, methods, and apparatus for biomolecular measurements, monitoring, and tracking uses a smartphone-based system. A biological sample, including, but not limited to blood, saliva, biopsy, or sweat, is collected on a modular diagnostic test platform, which is then inserted into a smartphone accessory. Optical, electrical, mechanical, or other means are used to transduce a biomolecular binding event, including antibody, aptamer, enzymatic, base-pair matching, or other biological recognition reaction and communicate the results with the smartphone. Some specific examples of targets include 25-hydroxyvitamin D, folic acid, DNA, or proteins from infectious agents, and zinc. The result can then be presented quantitatively or turned into a more consumer-friendly measurement (positive, negative, above average, etc.), displayed to the user, stored for later comparison, and communicated to a central hub location where medical professionals can provide additional review.
    Type: Application
    Filed: September 6, 2013
    Publication date: August 27, 2015
    Applicant: CORNELL UNIVERSITY
    Inventors: David Erickson, Matthew Mancuso, Seoho Lee
  • Publication number: 20150238967
    Abstract: Disclosed are methods and apparatus for solar-thermal microfluidic polymerase chain reaction. A device comprises a microfluidic chip including at least one PCR region, an energy absorption layer disposed adjacent to the microfluidic chip, a solar energy concentrator adapted to produce a plurality of temperature profiles on the microfluidic chip adapted to facilitate PCR, and a photomask disposed between the solar energy concentrator and the microfluidic chip.
    Type: Application
    Filed: September 18, 2013
    Publication date: August 27, 2015
    Applicant: CORNELL UNIVERSITY
    Inventors: David Erickson, Li Jiang, Matthew Mancuso
  • Publication number: 20150038361
    Abstract: Methods and systems for colorimetric detection of a target. Nucleic acid is obtained from a sample potentially containing two pathogens of interest, and is contacted with a plurality of nanoparticles. A first portion of the plurality of nanoparticles are functionalized with oligonucleotides complementary to a first region of the first target and oligonucleotides complementary to a second region of the first target, and a second portion of the plurality of nanoparticles are functionalized with oligonucleotides complementary to a first region of the second target and oligonucleotides complementary to a second region of the second target. The presence of the target nucleic acid causes a detectable colorimetric change, thereby diagnosing the presence of the pathogen.
    Type: Application
    Filed: February 14, 2013
    Publication date: February 5, 2015
    Inventors: David Erickson, Matthew Mancuso, Ethel Cesarman, Li Jiang