Patents by Inventor Matthew MCCLOREY

Matthew MCCLOREY has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Glucocorticoid “nintedanib” particles and their use
    Patent number: 11931368
    Abstract: Disclosed herein are particles of at least 95% by weight of a glucocorticoid that have a specific surface area of at least 10 m2/g, methods for making, such particles, and methods for their use as therapeutics. Also disclosed herein are particles of at least 95% by weight of an indolinone that have a specific surface area of at least 10 m2/g, methods for making such particles, and methods for-their use as therapeutics.
    Type: Grant
    Filed: September 28, 2018
    Date of Patent: March 19, 2024
    Assignee: CRITITECH, INC.
    Inventors: Michael Baltezor, Matthew McClorey, Joseph S. Farthing, Mark Williams, Jacob Sittenauer
  • Local delivery of antineoplastic particles in combination with systemic delivery of immunotherapeutic agents for the treatment of cancer
    Patent number: 11918691
    Abstract: Disclosed are combination therapy methods useful for the therapeutic treatment of cancer by combining local administration of compositions containing antineoplastic particles, such as taxane particles, with systemic administration of compositions containing immunotherapeutic agents. Local administration methods include topical application, pulmonary administration, intratumoral injection, intraperitoneal injection, arid intracystic injection.
    Type: Grant
    Filed: January 13, 2023
    Date of Patent: March 5, 2024
    Assignee: CRITITECH, INC.
    Inventors: Gere S. Dizerega, Michael Baltezor, Sam Campbell, Charles J. Decedue, Matthew McClorey, Holly Maulhardt
  • Treatment of Epithelial Cysts by Intracystic Injection of Antineoplastic Particles
    Publication number: 20230372234
    Abstract: Disclosed herein are methods for treating epithelial cysts, including pancreatic cysts, in a subject by intracystic injection of compositions comprising antineoplastic particles, including taxane particles such as paclitaxel particles and docetaxel particles.
    Type: Application
    Filed: July 13, 2023
    Publication date: November 23, 2023
    Inventors: Gere S. diZerega, Michael Baltezor, Charles J. Decedue, Sam Campbell, Matthew McClorey, Marc Iacobucci, Holly Maulhardt
  • Treatment of epithelial cysts by intracystic injection of antineoplastic particles
    Patent number: 11737972
    Abstract: Disclosed herein are methods for treating epithelial cysts, including pancreatic cysts, in a subject by intracystic injection of compositions comprising antineoplastic particles, including taxane particles such as paclitaxel particles and docetaxel particles.
    Type: Grant
    Filed: October 12, 2022
    Date of Patent: August 29, 2023
    Assignee: CRITITECH, INC.
    Inventors: Gere S. diZerega, Michael Baltezor, Charles J. Decedue, Sam Campbell, Matthew McClorey, Marc Iacobucci, Holly Maulhardt
  • Local delivery of antineoplastic particles in combination with systemic delivery of immunotherapeutic agents for the treatment of cancer
    Publication number: 20230263731
    Abstract: Disclosed are combination therapy methods useful for the therapeutic treatment of cancer by combining local administration of compositions containing antineoplastic particles, such as taxane particles, with systemic administration of compositions containing immunotherapeutic agents. Local administration methods include topical application, pulmonary administration, intratumoral injection, intraperitoneal injection, arid intracystic injection.
    Type: Application
    Filed: January 13, 2023
    Publication date: August 24, 2023
    Inventors: Gere S. DIZEREGA, Michael BALTEZOR, Sam CAMPBELL, Charles J. DECEDUE, Matthew MCCLOREY
  • Treatment of Epithelial Cysts by Intracystic Injection of Antineoplastic Particles
    Publication number: 20230111288
    Abstract: Disclosed herein are methods for treating epithelial cysts, including pancreatic cysts, in a subject by intracystic injection of compositions comprising antineoplastic particles, including taxane particles such as paclitaxel particles and docetaxel particles.
    Type: Application
    Filed: October 12, 2022
    Publication date: April 13, 2023
    Inventors: Gere S. diZerega, Michael Baltezor, Charles J. Decedue, Sam Campbell, Matthew McClorey, Marc Iacobucci, Holly Maulhardt
  • Local delivery of antineoplastic particles in combination with systemic delivery of immunotherapeutic agents for the treatment of cancer
    Patent number: 11583499
    Abstract: Disclosed are combination therapy methods useful for the therapeutic treatment of cancer by combining local administration of compositions containing antineoplastic particles, such as taxane particles, with systemic administration of compositions containing immunotherapeutic agents. Local administration methods include topical application, pulmonary administration, intratumoral injection, intraperitoneal injection, and intracystic injection.
    Type: Grant
    Filed: May 28, 2021
    Date of Patent: February 21, 2023
    Assignee: CritiTech, Inc.
    Inventors: Gere S. Dizerega, Michael Baltezor, Sam Campbell, Charles J. Decedue, Matthew McClorey
  • Treatment of epithelial cysts by intracystic injection of antineoplastic particles
    Patent number: 11523983
    Abstract: Disclosed herein are methods for treating epithelial cysts, including pancreatic cysts, in a subject by intracystic injection of compositions comprising antineoplastic particles, including taxane particles such as paclitaxel particles and docetaxel particles.
    Type: Grant
    Filed: May 10, 2021
    Date of Patent: December 13, 2022
    Assignee: CritiTech, Inc.
    Inventors: Gere S. diZerega, Michael Baltezor, Charles J. Decedue, Sam Campbell, Matthew McClorey, Marc Iacobucci, Holly Maulhardt
  • Treatment of Bladder Cancer by Local Administration of Taxane Particles
    Publication number: 20220096423
    Abstract: Disclosed herein are methods for treating and inhibiting the recurrence of bladder cancer by local administration of compositions comprising taxane particles such as docetaxel particles. Administration methods include intratumoral injection, direct injection into surgical tumor resection sites, and intravesical instillation.
    Type: Application
    Filed: October 1, 2021
    Publication date: March 31, 2022
    Inventors: Gere S. DIZEREGA, Michael BALTEZOR, Charles DECEDUE, Sam CAMPBELL, Matthew MCCLOREY
  • Local delivery of antineoplastic particles in combination with systemic delivery of immunotherapeutic agents for the treatment of cancer
    Publication number: 20220047513
    Abstract: Disclosed are combination therapy methods useful for the therapeutic treatment of cancer by combining local administration of compositions containing antineoplastic particles, such as taxane particles, with systemic administration of compositions containing immunotherapeutic agents. Local administration methods include topical application, pulmonary administration, intratumoral injection, intraperitoneal injection, and intracystic injection.
    Type: Application
    Filed: May 28, 2021
    Publication date: February 17, 2022
    Inventors: Gere S. DIZEREGA, Michael BALTEZOR, Sam CAMPBELL, Charles J. DECEDUE, Matthew MCCLOREY
  • Taxane Particles and Their Use
    Publication number: 20210393569
    Abstract: Compositions are provided that include having at least 95% by weight of a taxane, or a pharmaceutically acceptable salt thereof, where the particles have a mean bulk density between about 0.050 g/cm3 and about 0.15 g/cm3, and/or a specific surface area (SSA) of at least 18 m2/g, 20 m2/g, 25 m2/g, 30 m2/g, 32 m2/g, 34 m2/g, or 35 m2/g. Methods for making and using such compositions are also provided.
    Type: Application
    Filed: September 7, 2021
    Publication date: December 23, 2021
    Inventors: Michael BALTEZOR, Joseph FARTHING, Jake SITTENAUER, Jahna ESPINOSA, Samuel CAMPBELL, Matthew MCCLOREY, Julia K. FISCHER, Mark D. WILLIAMS, Gary E. CLAPP
  • CIPROFLOXACIN POLYMORPH AND ITS USE
    Publication number: 20210387961
    Abstract: The present disclosure relates to ciprofloxacin polymorphs and their use in treating infections.
    Type: Application
    Filed: August 13, 2021
    Publication date: December 16, 2021
    Inventors: Mark WILLIAMS, Jacob SITTENAUER, Shelby CLARK, Joseph FARTHING, Michael BALTEZOR, Matthew MCCLOREY
  • Methods for treating lung disorders
    Patent number: 11160754
    Abstract: Disclosed herein are compositions and methods for treating lung disorders including lung tumors by pulmonary administration of compositions comprising taxane particles such as docetaxel or paclitaxel particles.
    Type: Grant
    Filed: October 31, 2019
    Date of Patent: November 2, 2021
    Assignee: CritiTech, Inc.
    Inventors: Michael Baltezor, Matthew McClorey, William Johnston, Gere S. diZerega, James Verco
  • Taxane particles and their use
    Patent number: 11123322
    Abstract: Compositions are provided that include having at least 95% by weight of a taxane, or a pharmaceutically acceptable salt thereof, where the particles have a mean bulk density between about 0.050 g/cm3 and about 0.15 g/cm3, and/or a specific surface area (SSA) of at least 18 m2/g, 20 m2/g, 25 m2/g, 30 m2/g, 32 m2/g, 34 m2/g, or 35 m2/g. Methods for making and using such compositions are also provided.
    Type: Grant
    Filed: October 30, 2019
    Date of Patent: September 21, 2021
    Assignee: Crititech, Inc.
    Inventors: Michael Baltezor, Joseph Farthing, Jake Sittenauer, Jahna Espinosa, Samuel Campbell, Matthew McClorey, Julia K. Fischer, Mark D. Williams, Gary E. Clapp
  • Ciprofloxacin polymorph and its use
    Patent number: 11104663
    Abstract: The present disclosure relates to ciprofloxacin polymorphs and their use in treating infections.
    Type: Grant
    Filed: September 28, 2018
    Date of Patent: August 31, 2021
    Assignee: CritiTech, Inc.
    Inventors: Mark Williams, Jacob Sittenauer, Shelby Clark, Joseph Farthing, Michael Baltezor, Matthew McClorey
  • Treatment of Epithelial Cysts by Intracystic Injection of Antineoplastic Particles
    Publication number: 20210259959
    Abstract: Disclosed herein are methods for treating epithelial cysts, including pancreatic cysts, in a subject by intracystic injection of compositions comprising antineoplastic particles, including taxane particles such as paclitaxel particles and docetaxel particles.
    Type: Application
    Filed: May 10, 2021
    Publication date: August 26, 2021
    Inventors: Gere S. diZerega, Michael Baltezor, Charles J. Decedue, Sam Campbell, Matthew McClorey, Marc Iacobucci, Holly Maulhardt
  • METHODS FOR ISOLATING TUMOR-SPECIFIC IMMUNE CELLS FROM A SUBJECT FOR ADOPTIVE CELL THERAPY AND CANCER VACCINES
    Publication number: 20210214683
    Abstract: Disclosed are methods for the isolation of tumor-specific immune cells from subjects that have a malignant tumor and have received local administration of a composition comprising taxane particles to the malignant tumor, and use of such isolated immune cells in compositions for adoptive cell therapy and cancer vaccines.
    Type: Application
    Filed: April 12, 2019
    Publication date: July 15, 2021
    Inventors: Gere S. DIZEREGA, Holly MAULHARDT, Michael BALTEZOR, Sam CAMPBELL, Charles J. DECEDUE, William JOHNSTON, Matthew MCCLOREY, James VERCO
  • Local delivery of antineoplastic particles in combination with systemic delivery of immunotherapeutic agents for the treatment of cancer
    Patent number: 11058639
    Abstract: Disclosed are combination therapy methods useful for the therapeutic treatment of cancer by combining local administration of compositions containing antineoplastic particles, such as taxane particles, with systemic administration of compositions containing immunotherapeutic agents. Local administration methods include topical application, pulmonary administration, intratumoral injection, intraperitoneal injection, and intracystic injection.
    Type: Grant
    Filed: March 30, 2020
    Date of Patent: July 13, 2021
    Assignee: CritiTech, Inc.
    Inventors: Gere S. Dizerega, Michael Baltezor, Sam Campbell, Charles J. Decedue, Matthew McClorey
  • Taxane particles and their use
    Patent number: 10993927
    Abstract: Compositions are provided that include having at least 95% by weight of a taxane, or a pharmaceutically acceptable salt thereof, where the particles have a mean bulk density between about 0.050 g/cm3 and about 0.15 g/cm3, and/or a specific surface area (SSA) of at least 18 m2/g, 20 m2/g, 25 m2/g, 30 m2/g, 32 m2/g, 34 m2/g, or 35 m2/g. Methods for making and using such compositions are also provided.
    Type: Grant
    Filed: September 17, 2020
    Date of Patent: May 4, 2021
    Assignee: Crititech, Inc.
    Inventors: Michael Baltezor, Joseph Farthing, Jake Sittenauer, Jahna Espinosa, Samuel Campbell, Matthew McClorey, Julia K. Fischer, Mark D. Williams, Gary E. Clapp
  • Taxane Particles and Their Use
    Publication number: 20210000786
    Abstract: Compositions are provided that include having at least 95% by weight of a taxane, or a pharmaceutically acceptable salt thereof, where the particles have a mean bulk density between about 0.050 g/cm3 and about 0.15 g/cm3, and/or a specific surface area (SSA) of at least 18 m2/g, 20 m2/g, 25 m2/g, 30 m2/g, 32 m2/g, 34 m2/g, or 35 m2/g. Methods for making and using such compositions are also provided.
    Type: Application
    Filed: September 17, 2020
    Publication date: January 7, 2021
    Inventors: Michael BALTEZOR, Joseph FARTHING, Jake SITTENAUER, Jahna ESPINOSA, Samuel CAMPBELL, Matthew MCCLOREY, Julia K. FISCHER, Mark D. WILLIAMS, Gary E. CLAPP