Patents by Inventor Matthew McDonagh
Matthew McDonagh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240026319Abstract: The present invention relates to plant-produced angiogenins, to related plant cells, plant calli, plants, seeds and other plant parts and products derived therefrom and to uses of plant-produced angiogenins. The present invention also relates to expression of angiogenin genes in plants and to related nucleic acids, constructs and methods.Type: ApplicationFiled: May 19, 2023Publication date: January 25, 2024Applicant: Agriculture Victoria Services PTY LTDInventors: German Spangenberg, Aidyn Mouradov, Jianghui Wang, Benjamin Graeme Cocks, Matthew Knight, Matthew McDonagh
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Patent number: 11692183Abstract: The present invention relates to plant-produced angiogenins, to related plant cells, plant calli, plants, seeds and other plant parts and products derived therefrom and to uses of plant-produced angiogenins. The present invention also relates to expression of angiogenin genes in plants and to related nucleic acids, constructs and methods.Type: GrantFiled: May 21, 2019Date of Patent: July 4, 2023Assignee: Agriculture Victoria Services PTY LTDInventors: German Spangenberg, Aidyn Mouradov, Jianghui Wang, Benjamin Graeme Cocks, Matthew Knight, Matthew McDonagh
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Patent number: 11692185Abstract: The present invention relates to plant-produced angiogenins, to related plant cells, plant calli, plants, seeds and other plant parts and products derived therefrom and to uses of plant-produced angiogenins. The present invention also relates to expression of angiogenin genes in plants and to related nucleic acids, constructs and methods.Type: GrantFiled: March 16, 2020Date of Patent: July 4, 2023Assignee: Agriculture Victoria Services PTY LTDInventors: German Spangenberg, Aidyn Mouradov, Jianghui Wang, Benjamin Graeme Cocks, Matthew Knight, Matthew McDonagh
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Publication number: 20210032611Abstract: The present invention relates to plant-produced angiogenins, to related plant cells, plant calli, plants, seeds and other plant parts and products derived therefrom and to uses of plant-produced angiogenins. The present invention also relates to expression of angiogenin genes in plants and to related nucleic acids, constructs and methods.Type: ApplicationFiled: March 16, 2020Publication date: February 4, 2021Applicant: Agriculture Victoria Services PTY LTDInventors: German Spangenberg, Aidyn Mouradov, Jianghui Wang, Benjamin Graeme Cocks, Matthew Knight, Matthew McDonagh
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Publication number: 20190359960Abstract: The present invention relates to plant-produced angiogenins, to related plant cells, plant calli, plants, seeds and other plant parts and products derived therefrom and to uses of plant-produced angiogenins. The present invention also relates to expression of angiogenin genes in plants and to related nucleic acids, constructs and methods.Type: ApplicationFiled: May 21, 2019Publication date: November 28, 2019Applicant: Agriculture Victoria Services PTY LTDInventors: German Spangenberg, Aidyn Mouradov, Jianghui Wang, Benjamin Graeme Cocks, Matthew Knight, Matthew McDonagh
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Patent number: 10456453Abstract: The invention provides a method of treating a disorder characterised by elevated or dysregulated myostatin, disorders where the interaction between follistatin and angiogenin can be used to improve function in tissues, neurological diseases or disorders, spinal injuries or diseases, bone diseases or disorders, diseases involving glucose homeostasis, wound healing, neuroprotection, nervous system functional support or managing metabolic diseases, the method comprising administering an effective amount of angiogenin or an angiogenin agonist. Compositions and neutraceuticals comprising angiogenin are also provided.Type: GrantFiled: September 13, 2017Date of Patent: October 29, 2019Assignees: AGRICULTURE VICTORIA SERVICES PTY LTD, SAPUTO DAIRY AUSTRALIA PTY LIMITEDInventors: Matthew McDonagh, Benjamin Cocks, Angus Tester, Peter Hobman, Andrew Brown, Michelle Rowney
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Publication number: 20180000908Abstract: The invention provides a method of treating a disorder characterised by elevated or dysregulated myostatin, disorders where the interaction between follistatin and angiogenin can be used to improve function in tissues, neurological diseases or disorders, spinal injuries or diseases, bone diseases or disorders, diseases involving glucose homeostasis, wound healing, neuroprotection, nervous system functional support or managing metabolic diseases, the method comprising administering an effective amount of angiogenin or an angiogenin agonist. Compositions and neutraceuticals comprising angiogenin are also provided.Type: ApplicationFiled: September 13, 2017Publication date: January 4, 2018Inventors: Matthew MCDONAGH, Benjamin COCKS, Angus TESTER, Peter HOBMAN, Andrew BROWN, Michelle ROWNEY
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Patent number: 9789168Abstract: The invention provides a method of treating a disorder characterized by elevated or dysregulated myostatin, disorders where the interaction between follistatin and angiogenin can be used to improve function in tissues, neurological diseases or disorders, spinal injuries or diseases, bone diseases or disorders, diseases involving glucose homeostasis, wound healing, neuroprotection, nervous system functional support or managing metabolic diseases, the method comprising administering an effective amount of angiogenin or an angiogenin agonist. Compositions and neutraceuticals comprising angiogenin are also provided.Type: GrantFiled: July 28, 2015Date of Patent: October 17, 2017Assignees: AGRICULTURE VICTORIA SERVICES PTY LTD, Murray Goulburn Co-Operative Co., LimitedInventors: Matthew McDonagh, Benjamin Cocks, Angus Tester, Peter Hobman, Andrew Brown, Michelle Rowney
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Patent number: 9247766Abstract: The invention provides methods for enriching a milk extract for angiogenin, such methods involving separation by size, charge or immunoaffinity. The invention also provides the angiogenin enriched extract produced by the methods and provides them in pharmaceutical and neutraceutical compositions and foods for treating a variety of diseases or disorders that can be treated by angiogenin.Type: GrantFiled: May 14, 2009Date of Patent: February 2, 2016Assignees: Murray Goulburn Co-Operative Co., Limited, Agriculture Victoria Services Pty Ltd.Inventors: Matthew McDonagh, Benjamin Cocks, Angus Tester, Peter Hobman, Andrew Brown
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Publication number: 20160015791Abstract: The invention provides a method of treating a disorder characterised by elevated or dysregulated myostatin, disorders where the interaction between follistatin and angiogenin can be used to improve function in tissues, neurological diseases or disorders, spinal injuries or diseases, bone diseases or disorders, diseases involving glucose homeostasis, wound healing, neuroprotection, nervous system functional support or managing metabolic diseases, the method comprising administering an effective amount of angiogenin or an angiogenin agonist. Compositions and neutraceuticals comprising angiogenin are also provided.Type: ApplicationFiled: July 28, 2015Publication date: January 21, 2016Inventors: Matthew MCDONAGH, Benjamin COCKS, Angus TESTER, Peter HOBMAN
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Patent number: 9119818Abstract: The invention provides a method of treating a disorder characterized by elevated or dysregulated myostatin, disorders where the interaction between follistatin and angiogenin can be used to improve function in tissues, neurological diseases or disorders, spinal injuries or diseases, bone diseases or disorders, diseases involving glucose homeostasis, wound healing, neuroprotection, nervous system functional support or managing metabolic diseases, the method comprising administering an effective amount of angiogenin or an angiogenin agonist. Compositions and neutraceuticals comprising angiogenin are also provided.Type: GrantFiled: May 14, 2009Date of Patent: September 1, 2015Assignees: AGRICULTURE VICTORIA SERVICES PTY LTD, Murray Goulburn Co-Operative Co., LimitedInventors: Matthew McDonagh, Benjamin Cocks, Angus Tester, Peter Hobman
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Patent number: 8551547Abstract: The invention provides a process for the preparation of an angiogenin-enriched fraction from a milk product, the process comprising contacting the milk product with a cation exchange resin and eluting the angiogenin-enriched fraction from the cation exchange resin with a mobile phase. The invention also provides angiogenin-enriched fractions produced by process and food products, nutraceuticals and pharmaceutical comprising such angiogenin.Type: GrantFiled: November 9, 2007Date of Patent: October 8, 2013Assignees: Murray Goulburn Co-operative Co., Limited, Agriculture Victoria Services Pty Ltd.Inventors: Andrew Brown, Michelle Rowney, Peter Hobman, Matthew McDonagh, Angus Tester, Benjamin Cocks
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Publication number: 20130243728Abstract: The invention relates to a recombinant microorganism comprising a transgene encoding angiogenin and optionally follistatin, a food product, beverage product or animal feed produced from or comprising said microorganism and uses thereof.Type: ApplicationFiled: November 18, 2010Publication date: September 19, 2013Applicants: Agriculture Victoria Services PTY LTD, Murray Goulburn Co-Operative Co. LimitedInventors: Matthew McDonagh, Benjamin Cocks, Angus Tester, Ross Crittenden
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Publication number: 20130039889Abstract: The invention relates to a recombinant microorganism comprising a transgene encoding angiogenin and optionally follistatin, a food product, beverage product or animal feed produced from or comprising said microorganism and uses thereof.Type: ApplicationFiled: November 18, 2011Publication date: February 14, 2013Applicants: Agriculture Victoria Services PTY LTD, Murray Goulburn Co-Operative Co. LimitedInventors: Matthew McDonagh, Benjamin Cocks, Angus Tester, Ross Crittenden
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Publication number: 20120328591Abstract: The invention provides a method of improving the oral delivery of a therapeutic agent, comprising the step of linking the therapeutic agent to a carrier protein comprising angiogenin, fusion proteins or conjugates comprising angiogenin and a therapeutic agent and their use in medicine.Type: ApplicationFiled: November 18, 2010Publication date: December 27, 2012Applicants: AGRICULTURE VICTORIA SERVICES PTY LTD, MURRAY GOULBURN CO-OPERATIVE CO., LTD.Inventors: Matthew McDonagh, Angus Tester, Benjamin Cocks, Ross Crittenden, Jianghui Wang
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Publication number: 20120331575Abstract: The invention provides a non-human transgenic animal comprising a transgene encoding angiogenin and food products comprising or obtained from the non-human transgenic animal and uses thereof.Type: ApplicationFiled: November 18, 2010Publication date: December 27, 2012Applicants: Agriculture Victoria Services PTY LTD, Murray Goulburn Co-Operative Co. LimitedInventors: Peter Hobman, Matthew McDonagh, Benjamin Cocks, Angus Tester
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Publication number: 20120309092Abstract: The present invention relates to plant-produced angiogenins, to related plant cells, plant calli, plants, seeds and other plant parts and products derived therefrom and to uses of plant-produced angiogenins. The present invention also relates to expression of angiogenin genes in plants and to related nucleic acids, constructs and methods.Type: ApplicationFiled: November 18, 2010Publication date: December 6, 2012Applicant: Agriculture Victoria Services Pty LtdInventors: German Spangenberg, Aidyn Mouradov, Jianghui Wang, Benjamin Graeme Cocks, Matthew Knight, Matthew McDonagh
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Publication number: 20110262422Abstract: The invention provides a method of treatment of any disorder in which administration of angiogenin is beneficial wherein the angiogenin is administered orally. Particularly, the oral angiogenin does not require a carrier or excipient or for the protein to be encapsulated or subjected to any other mechanism to improve its oral bioavailability.Type: ApplicationFiled: May 14, 2009Publication date: October 27, 2011Applicants: MURRAY GOULBURN CO-OPERATIVE CO., LIMITED, AGRICULTURE VICTORIA SERVICES PTY LTD.Inventors: Benjamin Cocks, Angus Tester, Peter Hobman, Matthew McDonagh
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Publication number: 20110151016Abstract: The invention provides a method of treating a disorder characterised by elevated or dysregulated myostatin, disorders where the interaction between follistatin and angiogenin can be used to improve function in tissues, neurological diseases or disorders, spinal injuries or diseases, bone diseases or disorders, diseases involving glucose homeostasis, wound healing, neuro-protection, nervous system functional support or managing metabolic diseases, the method comprising administering an effective amount of angiogenin or an angiogenin agonist. Compositions and neutraceuticals comprising angiogenin are also provided.Type: ApplicationFiled: May 14, 2009Publication date: June 23, 2011Inventors: Matthew McDonagh, Benjamin Cocks, Angus Tester, Peter Hobman
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Publication number: 20110123514Abstract: The invention provides methods for enriching a milk extract for angiogenin, such methods involving separation by size, charge or immunoaffinity. The invention also provides the angiogenin enriched extract produced by the methods and provides them in pharmaceutical and neutraceutical compositions and foods for treating a variety of diseases or disorders that can be treated by angiogenin.Type: ApplicationFiled: May 14, 2009Publication date: May 26, 2011Inventors: Matthew McDonagh, Benjamin Cocks, Angus Tester, Peter Hobman, Andrew Brown