Abstract: A skateboard deck that is both stiff in one dimension and flexible in another dimension is disclosed. The deck includes an elongated body characterized by a longitudinal axis, a plurality of ribs, and a plurality of apertures. The plurality of ribs are long, narrow beams oriented substantially parallel to the longitudinal axis and integral with the bottom of the elongated body. The plurality of apertures are distributed in a plurality of rows also oriented substantially parallel to the longitudinal axis. The ribs and rows of apertures are interposed in an alternating pattern across the width of the deck. The resulting deck is stiff in the longitudinal direction yet flexible with respect to rotation about the longitudinal axis. The deck is therefore flexible enough to enable the front and rear trucks to rotate with respect to one another while still being rigid enough to withstand the weight of the rider.

Abstract: Materials and methods for using polypeptides containing fragments and variants of endostatin to treat fibrosis are described herein.

Abstract: A fill adapter for delivery of a medical liquid to a container has a body with a distal end, a proximal end, and a central bore extending between the distal end and the proximal end along a longitudinal axis. The central bore has an angled portion at the proximal end of the body such that a diameter of the central portion increases at the angled portion in a direction from the distal end to the proximal end. The fill adapter further has a flow controller disposed within the central bore at a distal end of the angled portion such that a gap is formed between an outer surface of the flow controller and an inner surface of the central bore. The flow controller is shaped to direct liquid flowing through the central bore to flow through the gap and along the angled portion of the central bore under a Coand? effect.

Abstract: Materials and methods for using polypeptides containing fragments and variants of endostatin to treat fibrosis are described herein.

Abstract: This document provides materials and methods for producing endostatin fusion polypeptides having anti-fibrotic activity. For example, provided herein are fusion polypeptides having an IgG Fc domain and a portion of human endostatin that can form high molecular weight multimers, as well as methods for producing such fusion polypeptides in plant cells.

Abstract: A fill adapter for delivery of a medical liquid to a container has a body with a distal end, a proximal end, and a central bore extending between the distal end and the proximal end along a longitudinal axis. The central bore has an angled portion at the proximal end of the body such that a diameter of the central portion increases at the angled portion in a direction from the distal end to the proximal end. The fill adapter further has a flow controller disposed within the central bore at a distal end of the angled portion such that a gap is formed between an outer surface of the flow controller and an inner surface of the central bore. The flow controller is shaped to direct liquid flowing through the central bore to flow through the gap and along the angled portion of the central bore under a Coand? effect.

Abstract: Materials and methods for using polypeptides containing fragments and variants of endostatin to treat fibrosis are described herein.

Abstract: A syringe for a fluid delivery system includes a pressure jacket having a distal end, a proximal end, and a throughbore therebetween. The syringe further includes a rolling diaphragm having a proximal end with an end wall for engaging a plunger, a distal end received within the throughbore of the pressure jacket. A sidewall extends between the proximal end and the distal end of the rolling diaphragm along a longitudinal axis. At least a portion of one of the sidewall and the end wall has non-uniform thickness. At least a portion of the sidewall is flexible and rolls upon itself when acted upon by the plunger such that an outer surface of the sidewall at a folding region is folded in a radially inward direction as the plunger is advanced from the proximal end to the distal end of the rolling diaphragm.