Abstract: A disposable thrombectomy maceration and aspiration system for macerating and aspirating thrombus or other obstructive material in a lumen of a vascular graft or vessel. The system includes three major components: a disposable integrated aspiration pump and fluid collection device for generating aspiration vacuum pressure and collecting macerated particulate, a disposable integrated thrombectomy and aspiration apparatus removably coupled to the device configured to macerate the thrombus with a motor powered maceration wire while including an aspiration pathway for aspirating the macerated particulate into the device, and a catheter removably coupled to the apparatus and covering a portion of the maceration wire for insertion into the patient to the thrombus site. The catheter is of sufficient size to allow the macerated particulate to be aspirated from a distal opening through the catheter and apparatus before being deposited into the fluid collection compartment of the device.

Abstract: A core-severing cannula for use with tissue biopsy devices, comprising a plurality of flexible fingers for severing a tissue core. The core-severing cannula is positioned coaxially outside of a core-cutting cannula, and is slidable relative to the core-cutting cannula. As the device is activated, the core cutting cannula and core-severing cannula advance together to cut a core of tissue. Subsequently, the core-severing cannula is advanced relative to the core cutting cannula, and the fingers of the core-severing cannula assume a closed position to sever the core from the target site.

Abstract: A computer-implemented method for completing transactions includes a first user creating and encrypting a message with an identifier associated with a second user. The first user then digitally signs the message with the encrypted message and a privately held key. From there, an exchange record is created which includes an identifier associated with the first user, an identifier associated with the second user, the encrypted message, and the digital signature of the first user. The second user validates the exchange record and decrypts the message by providing a privately held key that is associated with the second user's identifier. A verification record, which includes the identifier of the second user, the identifier of the first user, the encrypted message, and a digital signature of the second user, is then created. The exchange record and verification record together constitute a completed transaction.

Abstract: A computer-implemented method for completing transactions between two users includes creating and encrypting a message by a user. The message is encrypted with an identifier associated with a second user who will receive the message. Once encrypted, the first user digitally signs the message with the encrypted message and a privately held key. Then the first user sends the message to a processor where an exchange record is created and placed on a registry. The exchange record includes an identifier associated with the sending user, the identifier associated with the receiving user, the encrypted message, and the digital signature of the first user. Once the exchange record is created, the receiving user can query the registry for any exchange records that include the receiving user's identifier. The receiving user can then validate the record. The exchange record is validated with the identifier of the sending user.