Abstract: A three-dimensional print head apparatus may include a securing mechanism, a hopper, a nozzle, a heating system, and a fume extraction system. The securing mechanism may be adapted to secure to a wrist joint of a robotic arm. The hopper may have a cavity and a lower aperture and may be secured to the securing mechanism. The nozzle may have an upper aperture and a lower aperture. The heating system may be positioned along the barrel.

Abstract: An optics-integrated confinement apparatus system comprises a confinement apparatus chip having a confinement apparatus formed thereon and having at least one apparatus optical element disposed and/or formed thereon.

Abstract: A three-dimensional print head apparatus including a hopper, a nozzle, a barrel, and a heating system. The apparatus may further include a fume extraction system and a dry air purge system. The hopper may have a cavity and a lower aperture. The nozzle may have an upper aperture and a lower aperture. The heating system may be positioned along the barrel, and the dry air purge system may be in fluid communication with the hopper.

Abstract: A three-dimensional print head apparatus comprising a hopper, a nozzle, a barrel, a heating system, a fume extraction system, a dry air purge system, and an agitator. The hopper may having a cavity and may have a lower aperture. The nozzle may have an upper aperture and may have a lower aperture. The heating system may be positioned along at least a portion of the barrel, which may defined a heated zone of the barrel. The dry air purge system may be in fluid communication with the hopper. The agitator may have at least one paddle.

Abstract: An interlocking paver system including a polygon paver and a spacer paver is provided. The polygon paver may have a top level having a top level polygon paver perimeter and a bottom level secured to and protruding from the top level and having a bottom level polygon paver perimeter contained within the top level polygon paver perimeter. The spacer paver may have a top level having a top level spacer paver perimeter and a bottom level secured to and protruding from the top level and having a bottom level spacer paver perimeter extending beyond an entirety of the top level spacer paver perimeter. The spacer paver may be configured to selectively interlock with the polygon paver. The top level spacer paver perimeter, top level polygon paver perimeter, and bottom level spacer paver perimeter are different from one another.

Abstract: There is provided a turf cup assembly that attaches to a buried pop-up type sprinkler to blend a top of sprinkler both cosmetically and functionally with turf surrounding the sprinkler. The turf cup assembly includes a turf cup and a sleeve. The turf cup mounts to a riser of the pop-up type sprinkler. The turf cup contains soil and root structure of turf. The sleeve surrounds the turf cup and attaches to a top of a housing of a pop-up sprinkler. The sleeve can be at or slightly below grade, and the cup extends out of the sleeve during an irrigation cycle and retracts into the sleeve at the end of the irrigation cycle.

Abstract: Described herein is a method of treating a subject in need of treatment for pathological angiogenesis including administering to the subject a glycosaminoglycan linked either covalently or noncovalently to an anti-VEGF antibody, an anti-VEGF antibody fragment, an anti-VEGF protein, an anti-VEGF peptide, or an anti-VEGF aptamer. Also included is a glycosaminoglycan linked either covalently or noncovalently to an anti-VEGF antibody, an anti-VEGF antibody fragment, an anti-VEGF protein, an anti-VEGF peptide, or an anti-VEGF aptamer.

Abstract: A three-dimensional print head apparatus may include a securing mechanism, a hopper, a nozzle, a heating system, and a fume extraction system. The securing mechanism may be adapted to secure to a wrist joint of a robotic arm. The hopper may have a cavity and a lower aperture and may be secured to the securing mechanism. The nozzle may have an upper aperture and a lower aperture. The heating system may be positioned along the barrel.

Abstract: A three-dimensional print head apparatus including a securing mechanism, a hopper, a nozzle, a barrel, and a heating system. The securing mechanism is adapted to secure to a wrist joint of a robotic arm. The hopper is secured to the securing mechanism and has a cavity and a lower aperture. The nozzle has an upper aperture and a lower aperture. The barrel has an elongate, hollow member with a first end secured to the lower aperture of the hopper and a second end secured to the upper aperture of the nozzle. The heating system is positioned along the barrel.

Abstract: There is provided a turf cup assembly that attaches to a buried pop-up type sprinkler to blend a top of sprinkler both cosmetically and functionally with turf surrounding the sprinkler. The turf cup assembly includes a turf cup and a sleeve. The turf cup mounts to a riser of the pop-up type sprinkler. The turf cup contains soil and root structure of turf. The sleeve surrounds the turf cup and attaches to a top of a housing of a pop-up sprinkler. The sleeve can be at or slightly below grade, and the cup extends out of the sleeve during an irrigation cycle and retracts into the sleeve at the end of the irrigation cycle.

Abstract: An interlocking paver system including a polygon paver and a spacer paver is provided. The polygon paver may have a top level having a top level polygon paver perimeter and a bottom level secured to and protruding from the top level and having a bottom level polygon paver perimeter contained within the top level polygon paver perimeter. The spacer paver may have a top level having a top level spacer paver perimeter and a bottom level secured to and protruding from the top level and having a bottom level spacer paver perimeter extending beyond an entirety of the top level spacer paver perimeter The spacer paver may be configured to selectively interlock with the polygon paver. The top level spacer paver perimeter, top level polygon paver perimeter, and bottom level spacer paver perimeter are different from one another.

Abstract: There is provided a turf cup assembly that attaches to a buried pop-up type sprinkler to blend a top of sprinkler both cosmetically and functionally with turf surrounding the sprinkler. The turf cup assembly includes a turf cup and a sleeve. The turf cup mounts to a riser of the pop-up type sprinkler. The turf cup contains soil and root structure of turf. The sleeve surrounds the turf cup and attaches to a top of a housing of a pop-up sprinkler. The sleeve can be at or slightly below grade, and the cup extends out of the sleeve during an irrigation cycle and retracts into the sleeve at the end of the irrigation cycle.

Abstract: An interlocking paver system including polygon and spacer pavers. The polygon paver has a longitudinal axis extending from a first to a second side and a transverse axis orthogonal to the longitudinal axis and extending from a third to a fourth side. The spacer paver has a longitudinal axis extending from a first to a second side and a transverse axis orthogonal to the longitudinal axis and extending from a third to a fourth side. Both the polygon and spacer pavers are symmetrical about the longitudinal and transverse axes. The spacer paver is configured to selectively interlock with the polygon paver with either of the third or fourth side of the polygon paver adjacent either of the first or second side of the spacer paver and either of the first or second side of the polygon paver adjacent either of the third or fourth side of the spacer paver.

Abstract: A three-dimensional print head apparatus including a securing mechanism, a hopper, a nozzle, a barrel, and a heating system. The securing mechanism is adapted to secure to a wrist joint of a robotic arm. The hopper is secured to the securing mechanism and has a cavity and a lower aperture. The nozzle has an upper aperture and a lower aperture. The barrel has an elongate, hollow member with a first end secured to the lower aperture of the hopper and a second end secured to the upper aperture of the nozzle. The heating system is positioned along the barrel.

Abstract: An interlocking paver system including polygon and spacer pavers. The polygon paver has a longitudinal axis extending from a first to a second side and a transverse axis orthogonal to the longitudinal axis and extending from a third to a fourth side. The spacer paver has a longitudinal axis extending from a first to a second side and a transverse axis orthogonal to the longitudinal axis and extending from a third to a fourth side. Both the polygon and spacer pavers are symmetrical about the longitudinal and transverse axes. The spacer paver is configured to selectively interlock with the polygon paver with either of the third or fourth side of the polygon paver adjacent either of the first or second side of the spacer paver and either of the first or second side of the polygon paver adjacent either of the third or fourth side of the spacer paver.

Abstract: There is provided a turf cup assembly that attaches to a buried pop-up type sprinkler to blend a top of sprinkler both cosmetically and functionally with turf surrounding the sprinkler. The turf cup assembly includes a turf cup and a sleeve. The turf cup mounts to a riser of the pop-up type sprinkler. The turf cup contains soil and root structure of turf. The sleeve surrounds the turf cup and attaches to a top of a housing of a pop-up sprinkler. The sleeve can be at or slightly below grade, and the cup extends out of the sleeve during an irrigation cycle and retracts into the sleeve at the end of the irrigation cycle.

Abstract: The present invention is directed to methods for inhibition of histone acetyltransferases using glycosaminoglycans. The invention is further directed to methods for treating disorders associated with hyperacetylation by administration of glycosaminoglycans to a patient in need thereof. In one preferred embodiment, the glycosaminoglycan is a heparin or heparan sulfate oligosaccharide. Studies show that removal of sulfate residues from the O-positions of either the uronic acid or the glucosamine did not eliminate the inhibitory activity of heparan sulfate. Since a majority of heparan sulfate binding proteins appear to require O-sulfation, molecules without certain O-sulfations can be used to inhibit HATs while not interacting with most known heparin-binding proteins. In addition, specific sequences of heparin/heparan sulfate can be used to specifically inhibit various HATs.

Abstract: A device comprising an extracellular matrix having an internal pH between 4.0 and 6.0 is discussed. This matrix contains heparin or a heparin-related compound such as heparan sulfate. Preferably the matrix also contains fibronectin or a fragment thereof. The matrix will bind to a protein having a pH dependent binding to heparin such as VEGF, preferably VEGF 121 or VEGF 165. The device will release the protein as the pH increases to physiological pH, such as 7.0 to 7.5. The device can be used to deliver a drug to a specific site. For example, with VEGF to a site in need of angiogenesis.

Abstract: One embodiment of the present invention provides an organic light emitting device comprising an anode, a cathode, and an organic layer disposed between the anode and the cathode, wherein the organic layer comprises an arylpyrene compound. In another embodiment, the present invention also provides organic light emitting devices comprising an anode, a cathode, and an organic layer disposed between the anode and the cathode, wherein the organic layer comprises an arylpyrene compound doped in an anthracene host, preferably ADN. Another embodiment of the present invention provides specific arylpyrene compounds.

Abstract: A composition and method are provided for inhibition of vascular smooth muscle cell proliferation following injury to the endothelial cell lining of a blood vessel such as resulting from angioplasty, vascular bypass surgery or organ transplantation. The composition is a matrix such as a biodegradable hydrogel made of a synthetic polymer, protein or polysaccharide seeded with vascular endothelial cells which can be xenografts, allografts or autografts, or genetically engineered cells. Attachment of cells to the matrix can be enhanced by coating with collagen, laminin, fibronectin, fibrin, basement membrane components or attachment peptides. Biologically active compounds such as anti-inflammatory agents may also be contained in the matrix. In the method, the matrix containing endothelial cells is implanted in a patient at a site adjacent the injury such as by wrapping the matrix around the blood vessel.